This article will tell you what causes diabetes. There is still much research being done into diabetes, what its causes are and how it can be detected. Unfortunately, one of the biggest problems is people not realizing they have diabetes. They don't do anything until they see other severe symptoms and by then it's often too late. Only approximately 10% of sufferers have type 1 diabetes. This is usually diagnosed in childhood; hence the name juvenile onset diabetes. However, it can technically occur into adulthood. Type 1 is largely still a mystery. The body, for some reason, destroys its own insulin producing cells. This leaves the person with no insulin. The sufferer is then completely reliant on being treated with insulin. There are genetic factors at play with the onset of type 1 diabetes. There can other factors as well, such as certain viruses or other environmental causes. Type
Differential Contribution of Diabetes and the Ren2 Gene to Glomerular Pathology in Diabetic (mREN-2)27 RatsNarrowing the scope of utility for (mREN-2)27 rats may help to create better methods for researching diabetic nephropathy. Laboratory Investigation (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Longitudinal examination of cervical volume and vascularization changes during the antepartum and postpartum period using three-dimensional and power Doppler ultrasoundJournal of Perinatal Medicine 38 (5): 461-465 Abstract Objective: To assess longitudinally the changes in cervical volume and vascularization during the peripartum period using three-dimensional ultrasound (3D US) and power Doppler and to determine whether these measures change with gestational complications. Methods: Longitudinal measurements of cervical dimensions by transvaginal 3D US and power Doppler using the virtual organ computer-aided analysis program were performed at 11?14, 22?24, 32?34 weeks' gestation, and at 6 weeks' postpartum in 111 pregnant women. Comparisons were made between women who delivered at term (vs. preterm), nulliparous (vs. parous), with (vs. without) pre-eclampsia and those with (vs. without) gestational diabetes. Results: After establishing reference ...Pcif1 modulates Pdx1 protein stability and pancreatic {beta} cell function and survival in miceThe homeodomain transcription factor pancreatic duodenal homeobox 1 (Pdx1) is a major mediator of insulin transcription and a key regulator of the β cell phenotype. Heterozygous mutations in PDX1 are associated with the development of diabetes in humans. Understanding how Pdx1 expression levels are controlled is therefore of intense interest in the study and treatment of diabetes. Pdx1 C terminus–interacting factor-1 (Pcif1, also known as SPOP) is a nuclear protein that inhibits Pdx1 transactivation. Here, we show that Pcif1 targets Pdx1 for ubiquitination and proteasomal degradation. Silencing of Pcif1 increased Pdx1 protein levels in cultured mouse β cells, and Pcif1 heterozygosity normalized Pdx1 protein levels in Pdx1+/– mouse islets, thereby increasing ...How do organisms make dietary choices?When given a choice, organisms will choose a diet that maintains a nutritional balance in tune with their needs. That choice, studied in fruit flies for the first time, is regulated by activity in a molecular pathway involved in aging, cancer and diabetes. Humans share the same molecular pathway. The study, the first to be done in a genetically tractable lab animal, could lead to treatments that would "reboot" metabolic pathways in individuals who are obese or suffer from diabetes. (Source: ScienceDaily Headlines)Children who eat vended snack foods face chronic health problems, poor diet, study findsSchool children who consume foods purchased in vending machines are more likely to develop poor diet quality -- and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to new research. (Source: ScienceDaily Headlines)An Economic Evaluation of Colesevelam when Added to Metformin-, Insulin- or Sulfonylurea-Based Therapies in Patients with Uncontrolled Type 2 Diabetes Mellitus(Source: PharmacoEconomics)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Factor Structure and Measurement Invariance of a 10-Item Decisional Balance Scale: Longitudinal and Subgroup Examination Within an Adult Diabetic Sample(Source: Measurement in Physical Education and Exercise Science)Frequent Reoccurrence of Hypoglycemia in a Type 2 Diabetic Patient with Insulin Antibodies(Source: Molecular Diagnosis)Dr Oz colon polyps raises question of "spontaneous disease" without cause(NaturalNews) Dr Oz was recently found to have a precancerous colon polyp which was surgically removed. Following this experience, he appears to be surprised and confused about the origin of the condition, and he credits colonoscopy screening with saving his life.Dr Oz even seems to think he has a perfect health record, saying, "I have done everything right. I don't have any family history, and yet I'm high risk now." His personal physician, meanwhile, is implying that even though Dr Oz's "healthy" diet was perfect, it wasn't enough to prevent colon polyps, and therefore you might get them too. (And therefore everybody should get screened...)Dr Jonathan Lapook, went on to say "...no matter what you do, you can't totally eliminate your risk of developing this disease, which is expected to s...Association of doctor specialty with diabetic patient risk of hospitalization due to diabetic ketoacidosis: a national population?based study in Taiwan(Source: Journal of Evaluation in Clinical Practice)Mild BNP may indicate LV dysfunction in diabeticsDutch researchers report that slightly elevated B-type natriuretic peptide levels are associated with increased left ventricular mass and diastolic dysfunction in patients with Type 2 diabetes. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Celebrating World Diabetes Day and preparing for the battles ahead(Source: Diabetes Research and Clinical Practice)Influence of Left Ventricular Dysfunction (Diastolic Versus Systolic) on Long-Term Prognosis in Patients With Versus Without Diabetes Mellitus Having Elective Peripheral Arterial SurgeryIn conclusion, diabetic patients with PAD have an increased prevalence of isolated systolic and combined LVD. In patients with PAD the presence of isolated diastolic, systolic, or combined LVD was independently and equally associated with increased cardiovascular mortality, irrespective of the concomitant presence of DM. (Source: The American Journal of Cardiology)Involvement of the Basilar Artery in Diabetes Mellitus: An MRI Study of Brainstem InfarctionsEur Neurol 2010;64:230–235 (DOI:10.1159/000319924) (Source: Karger Publishers)Peroxisome Proliferator-Activated Receptor-γ Agonist Rosiglitazone Prevents Albuminuria but Not Glomerulosclerosis in Experimental DiabetesAm J Nephrol 2010;32:393–402 (DOI:10.1159/000320129) (Source: Karger Publishers)Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in MiceFindings reflect those of population studies in humans, researchers say (Source: Pharmacy News - Doctors Lounge)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Bariatric Surgery Cost-Effective in Very Obese With DiabetesBoth gastric bypass and gastric banding are cost-effective ways to reduce diabetes-associated
complications and mortality among severely obese individuals with diabetes, according to research published in the
September issue of Diabetes Care. (Source: Modern Medicine)Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic ?-cells: protective role of p62-positive cytoplasmic inclusionsHuman-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions
Cell Death and Differentiation advance online publication, September 3, 2010. doi:10.1038/cdd.2010.111
Authors: J F Rivera, T Gurlo, M Daval, C J Huang, A V Matveyenko, P C Butler
& S Costes (Source: Cell Death and Differentiation)FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuriaOVE26 (OVE) diabetic mice on the inbred strain FVB are a valuable model of diabetic nephropathy that excretes the highest amount of urine albumin of all diabetic mouse models. Crossing of OVE mice to C57BL6 or DBA2 mice reduced albuminuria 17-fold in F1 diabetic offspring without reducing diabetes. When comparing renal histology of OVE mice on the FVB background to F1 C57BL6 crosses, we found that the F1 kidneys had significantly smaller glomeruli, much less albumin accumulation in tubules, reduced mesangial matrix expansion, and less interstitial fibrosis. A genome scan of 108 OVE-positive N2 offspring for albuminuria revealed one significant peak on chromosome 11 and nearly significant peaks on chromosomes 9, 13, and 19. Homozygosity for the FVB genotype for peaks on chromosomes 11, 13, ...The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouseIn conclusion, in the diabetic Apo-E–/– mouse, rosuvastatin confers renal benefits that are independent of lipid lowering and equivalent or greater to those observed with candesartan. The combination treatment is not superior to monotherapies. (Source: AJP: Renal Physiology)Expression patterns of connective tissue growth factor and of TGF-{beta} isoforms during glomerular injury recapitulate glomerulogenesisTransforming growth factor (TGF)-β1, -β2, and -β3 are involved in control of wound repair and development of fibrosis. Connective tissue growth factor (CTGF) expression is stimulated by all TGF-β isoforms and is abundant in glomerulosclerosis and other fibrotic disorders. CTGF is hypothesized to mediate profibrotic effects of TGF-β1 or to facilitate interaction of TGF-β1 with its receptor, but its interactions with TGF-β isoforms in nonpathological conditions are unexplored so far. Tissue repair and remodeling may recapitulate gene transcription at play in organogenesis. To further delineate the relationship between CTGF and TGF-β, we compared expression patterns of CTGF and TGF-β isoforms in rat and human glomerulogenesis and in various human g...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>School Children Who Eat Vending Machine Foods Face Increased Risks for Chronic Health Problems, Poor DietSeptember 2, 2010 (U-M) - School children who consume foods purchased in vending machines are more likely to develop poor diet quality ? and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School.
The study also looked at foods sold in school stores, snack bars and other related sales that compete with USDA lunch program offerings and found that these pose the same health and diet risks in school-aged children.
read more (Source: Diabetes News from dLife.com)Acasti Pharma Inc. Reports Positive Impacts on Cardiometabolic Associated DisordersLAVAL, Quebec, Sept. 2, 2010 (GLOBE NEWSWIRE) -- This release replaces and supersedes the press release sent earlier today. Acasti Pharma Inc., a subsidiary of Neptune Technologies & Bioressources Inc. ("Neptune") (Nasdaq:NEPT) (TSX-V:NTB) reports significant results on the effects of its anti-dyslipidemic investigational drug candidate CaPre(tm) on C-reactive protein (CRP) levels, a biomarker of CardioVascular Disease risk (CVD) and associated with diabetes and obesity. (Source: Medical News (via PRIMEZONE))Sugar not a painkiller for babiesConclusion
This study has used objective measures of pain in a small sample of infants and used careful blinding and randomisation to reduce bias. There are a few limitations due to the study size, but the conclusions are likely to challenge the currently held belief that sugar is an effective treatment for the pain of minor procedures in infants. The limitations mentioned by the researchers were:
The small sample size of 44 infants analysed, which could mean that this study was not powered to observe subtle effects that sucrose might have on the brain processes used for pain.
A measure of pain in infants is necessarily indirect (because they cannot describe the sensation), and so even though the electrophysiological measures reported in this study are more objective it is not clear ...How Fish Oil Fights InflammationOmega-3 fatty acids work via a specific receptor and may combat diabetes as well (Source: ScienceNOW)Moving Diabetes Genetics Beyond Genome-Wide Association StudiesDr. Ali Torkamani summarizes key sessions from the American Diabetes Association's 70th Scientific Sessions and discusses how genetic investigations can assist in our understanding of type 1 and type 2 diabetes. Medscape Genomic Medicine (Source: Medscape Pathology Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Lower Blood Pressure Goal Benefits African-Americans with Chronic Kidney Disease, Protein in the UrineSource: National Institute of Diabetes and Digestive and Kidney Diseases -
Related MedlinePlus Pages: African-American Health, Kidney Diseases (Source: MedlinePlus Health News)Long Term Data Presented at ESC 2010 Further Support the Benefit of The CYPHER(R) Sirolimus Drug-Eluting Stent Compared to The ENDEAVOR(R) Zotarolimus-Eluting Stent in Important High-Risk SubgroupsAdditional Analysis of 18 Month Data of the SORT OUT III Trial Provides Detail on Safety and Efficacy Outcomes in Patients With Diabetes, Acute Coronary Syndrome, or Treatment of Multiple Lesions
STOCKHOLM, September 2, 2010 (HSMN NewsFeed) --Three ne... Devices, Interventional CardiologyCordis, CYPHER, Sirolimus, Drug Eluting Stent, Zotarolimus, Medtronic (Source: HSMN NewsFeed)EMAS Publishes Position Statements About the Post-Reproductive Health of WomenSeptember 2, 2010 (EurekAlert) - Elsevier announced today the publication of four important position statements from the European Menopause and Andropause Society (EMAS) in the journal Maturitas on common management problems in the post-reproductive health of women. The statements cover the management of the menopause in the context of obesity, epilepsy, endometriosis and premature ovarian failure. Each statement has summary recommendations as a quick aid for the busy clinician.
read more (Source: Diabetes News from dLife.com)Diabetes 2 Drug Metformin May Protect Against Lung Cancer In SmokersTwo studies reveal that smokers may have a significantly lower risk of developing lung cancer and colorectal cancer with the drug metformin, which is commonly prescribed for diabetes type 2 treatment, the medical journal Cancer Prevention Research informs. Metformin, originally sold as Glucophage, is the first-line drug of choice for diabetes type 2 patients, especially those who are obese or overweight, as well as diabetes patients with normal kidney function. Metformin may have the following brand names: Fortamet, Glucophage, Glucophage XR, Glumetza, or Riomet... (Source: Health News from Medical News Today)Halozyme Begins Phase 2 Clinical Trials With Insulin Analogs Lispro and Aspart With rHuPH20 In Type 1 And Type 2 DiabetesHalozyme Therapeutics, Inc. (Nasdaq: HALO) today announced the initiation of two Phase 2 Ultrafast Insulin treatment studies that utilize its rHuPH20 hyaluronidase enzyme (PH20) in combination with the two leading commercially available mealtime analogs: insulin aspart, the active ingredient in NovoLog®, and insulin lispro, the active ingredient in Humalog®. (Source: Pharmaceutical Online News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Acasti Pharma Inc. Reports Positive Impacts on Obesity and Cardiometabolic Associated DisordersLAVAL, Quebec, Sept. 2, 2010 (GLOBE NEWSWIRE) -- Acasti Pharma Inc., a subsidiary of Neptune Technologies & Bioressources Inc. ("Neptune") (Nasdaq:NEPT) (TSX-V:NTB) reports significant results on the effects of its anti-dyslipidemic investigational drug candidate CaPre(tm) on C-reactive protein (CRP) levels, a biomarker of CardioVascular Disease risk (CVD) and associated with diabetes and obesity. (Source: Medical News (via PRIMEZONE))Agent Orange Cases Expanded; Added Costs Raise Fiscal ConcernsThe Associated Press/Washington Post: Hundreds of thousands of Vietnam War veterans are receiving disability compensation for diseases normally associated with aging - not combat - because of the possibility of a link Agent Orange exposure. The diseases in question range from diabetes, for which 270,000 veterans receive Agent Orange-related checks, to erectile dysfunction. "And taxpayers may soon be responsible for even more: VA said Monday that it will add heart disease, Parkinson's disease and certain types of leukemia to the list of conditions that might be connected to Agent Orange... (Source: Health News from Medical News Today)Familial prevalence of autoimmune disorders in multiple sclerosis in Northern GreeceConclusions: There is a longitudinally increased frequency of additional autoimmune disorders among multiple sclerosis family members, probably related to immunomodulatory therapy. (Source: Multiple Sclerosis)Coronary revascularisation in the patient with diabetes: balancing risk and benefit(Source: Heart)Association between admission hypoglycaemia and in-hospital and 3-year mortality in older patients with acute myocardial infarctionConclusions
In older patients with AMI, increased as well as decreased admission FPG levels could predict higher in-hospital and 3-year mortality. There was a striking U-shaped relationship between admission FPG levels and short- and long-term mortality. An initial admission FPG level ≥ 5.1 to≤7.0 mmol/l may be desirable because it was associated with better clinical outcomes. (Source: Heart)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Unilife Corporation Secures FDA 510k Clearance For The Unitract? 1mL Tuberculin SyringeUnilife Corporation ("Unilife" or "Company") (Nasdaq: UNIS, ASX: UNS), announced that its Unitract? Tuberculin (TB) Syringe has received 510(k) market clearance from the U.S. Food and Drug Administration (FDA). The Unitract? TB syringe is a variant of the Unitract? 1mL Insulin Syringe for which Unilife secured FDA clearance earlier this year. Unlike insulin syringes which are primarily used by people with diabetes, TB syringes are used for the administration of a range of therapeutic drugs and vaccines within acute-care hospitals and other healthcare facilities... (Source: Health News from Medical News Today)Telemedicine Helps Native AmericansSource: Carolyn Bloch, Federal Telemedicine News Content: “The University of California, Davis School of Medicine is using grant funding to train Native American communities in the state. The training sites include the Round Valley Indian Tribes of Covelo, Mendocino County, and communities served by Northern Valley Indian Health Inc. that includes Glenn County and portions [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)Original Article: Potential CYP2C9?mediated drug?drug interactions in hospitalized type 2 diabetes mellitus patients treated with the sulphonylureas glibenclamide, glimepiride or glipizideAbstract.? (Source: Journal of Internal Medicine)pSivida Announces Iluvien(R) Receives FDA Priority Review For Treatment Of Diabetic Macular EdemapSivida Corp. (NASDAQ:PSDV) (ASX:PVA), a leader in the development of sustained release back of the eye drug delivery systems for difficult-to-treat conditions, announced that its licensee, Alimera Sciences (NASDAQ:ALIM) has been notified that the U.S. Food and Drug Administration (FDA) has granted Priority Review status for the New Drug Application (NDA) filed for Iluvien for the treatment diabetic macular edema (DME). FDA Priority Review status is given to therapies that offer major advances in treatment, or provide a treatment where no adequate therapy exists... (Source: Health News from Medical News Today)New Study Singles Out Factors Linked To Cognitive Deficits In Type 2 DiabetesOlder adults with diabetes who have high blood pressure, walk slowly or lose their balance, or believe they're in bad health, are significantly more likely to have weaker memory and slower, more rigid cognitive processing than those without these problems, according to a new study published by the American Psychological Association. These three health factors stood out from more than a dozen suspected to shape how Type 2 diabetes is frequently shadowed by cognitive impairment, including dementia... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Growing Obesity, Diabetes Epidemics In CaliforniaA majority of adults in California are obese or overweight, and more than 2 million have been diagnosed with diabetes, according to a new study from the UCLA Center for Health Policy Research. Both conditions - which are related to each other as well as to heart disease - increased significantly in just six years, with the prevalence of diabetes alone jumping nearly 26 percent between 2001 and 2007. The "epidemic" of obesity and diabetes leaves no racial, ethnic, economic or geographic segment of the state unscathed, according to the researchers... (Source: Health News from Medical News Today)Angola: Diabetes Association Set Up in HuílaAn Angolan Diabetes Association (ASDA) was set up on Tuesday, in Lubango City, in the southern Huíla Province, aimed at warning, training and educating sufferers of this disease on how to fight against diabetes. (Source: AllAfrica News: Health and Medicine)ACE I-ARB combination therapy not detrimental to severely hypertensive diabeticsAustralian researchers suggest that combined ACE inhibitor and angiotensin receptor blocker antihypertensive therapy does not produce more renal damage than monotherapy with either drug in diabetes patients with severe hypertension. (Source: MedWire News - Diabetes)Increased risk of death in men with insomnia and a short sleep durationMen with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period, according to a new study. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: ScienceDaily Headlines)Bigger role for pharmacists plannedPharmacies in Scotland will provide a five-star chronic medication service for patients with conditions like diabetes and high blood pressure (Source: Pharmacy Europe)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Potential remains for PPAR-targeted drugsNature Reviews Drug Discovery 9, 668 (2010). doi:10.1038/nrd3271
Author: Dan Jones
The controversy over the diabetes drug rosiglitazone (Avandia; GlaxoSmithKline), a peroxisome proliferator-activated receptor-? agonist, has undermined confidence in developing drugs that target this family of nuclear receptors, but some companies still see promise in the field. (Source: Nature Reviews Drug Discovery)Deal watch: Metabolex and Sanofi?Aventis partner on GPCR agonists for type 2 diabetesNature Reviews Drug Discovery 9, 670 (2010). doi:10.1038/nrd3255
Metabolex has entered into an agreement with Sanofi?Aventis for the development of small molecules that target G protein-coupled receptor 119 (GPR119), the most advanced of which is in a Phase II trial for the treatment of type 2 diabetes (T2D). Metabolex will receive upfront and (Source: Nature Reviews Drug Discovery)Children who eat vended snack foods face chronic health problems, poor diet(University of Michigan Health System) School children who consume foods purchased in vending machines are more likely to develop poor diet quality -- and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School. (Source: EurekAlert! - Biology)Variation in Quality of Care Indicators for Diabetes in a National Sample of Veterans and Non-VeteransDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)Most diabetics need better BP control to reach targetsBelgian researchers report that only 16% of patients with Type 2 diabetes achieve the target blood pressure of 130/80 mmHg recommended by American and European regulatory bodies such as the European Society of Hypertension. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Diabetes drug can reduce risk of cancer, researchers findMetformin reduced the development of lung tumors in mice by more than 70%. Clinical trials on humans for lung, breast and prostate cancer are being organized.A growing body of evidence suggests that the widely used diabetes drug metformin can reduce the risk of cancer, researchers said Wednesday. (Source: Los Angeles Times - Science)Diabetes drug can reduce risk of cancer, researchers findMetformin reduced the development of lung tumors in mice by more than 70%. Clinical trials on humans for lung, breast and prostate cancer are being organized.A growing body of evidence suggests that the widely used diabetes drug metformin can reduce the risk of cancer, researchers said Wednesday. (Source: L.A. Times - Health)Sphingolipids as Signaling and Regulatory Moleculesseries:Advances in Experimental Medicine and BiologyThis book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases. (Source: Springer Biomedical Sciences titles)Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitusAuthors: G Yang, C Pan
& J Lu (Source: International Journal of Impotence Research)Epidemiological and economic burden of metabolic syndrome and its consequences in patients with hypertension in Germany, Spain and Italy; a prevalence-based model.Conclusion:
The presence of metabolic syndrome in patients with hypertension significantly inflates economic burden and costs are likely to increase in the future due to an aging population and an increase in the prevalence of components of metabolic syndrome. (Source: BMC Public Health - Latest articles)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Increased levels of CRP and MCP-1 are associated with previously unknown abnormal glucose regulation in patients with acute STEMI: a cohort study.Conclusion:
Elevated levels of CRP and MCP-1 measured in patients early after an acute STEMI were associated with abnormal glucose regulation classified by an OGTT at three-month follow-up. No significant associations were observed between inflammatory markers and hyperglycaemia measured during the acute STEMI. (Source: Cardiovascular Diabetology)FDA updates drug label for tigecycline (Tygacil®) to warn of increased mortality riskSource: FDA
Area: News
The FDA has issued a reminder to healthcare professionals of an increased mortality risk associated with the use of the intravenous antibiotic tigecycline (Tygacil®) compared to that of other drugs used to treat a variety of serious infections. The increased risk was more pronounced in patients treated for hospital-acquired pneumonia, especially ventilator-associated pneumonia, but was also seen in patients with complicated skin and skin structure infections, complicated intra-abdominal infections and diabetic foot infections. The Agency has updated sections of the drug label to include information about this increased mortality risk and suggested that alternatives should be considered in patients with severe infections. (Source: NeLM - News)Survey on access to insulin pump therapySource: Medical Technology Group (MTG),
Area: News
The Medical Technology Group (MTG), a coalition of patient groups, research charities and medical device manufacturers, has published the findings of its survey of 152 PCTs about access to insulin pump therapy, which confirmed that overall uptake and utilisation for insulin pump therapy remains extremely low.
The survey found that:
. The average rate of insulin pump provision for people with type 1 diabetes is 3.9% compared to the 12% benchmark recommended by NICE.
. Two PCTs gave information which suggests they are providing insulin pumps in line with the NICE benchmark.
. Five out of 113 PCTs have a strategy in place to implement NICE guidance on insulin pumps in line with their...Intensive BP control in black patients with CKD may reduce disease progression in someSource: New England Journal of Medicine
Area: News
Further analysis of long-term follow up of patients from the AASK study found indications that intensive blood pressure (BP) control might reduce chronic kidney disease (CKD) progression in those with baseline proteinuria.
AASK tested antihypertensive regimens based on three drug groups in non-diabetic African-American patients with hypertension and signs of renal impairment, to determine whether any drug class was superior and whether more intensive BP control had advantages. Drugs used were ramipril, amlodipine, and metoprolol: the amlodipine arm was stopped early due to poorer outcomes. The results from the original trial, published in 2002 (JAMA 2002; 288(19): 2421-31), did not show any superiority for intensive BP control ...Readily available clinical descriptions can help assess cardiovascular event risk in atherosclerotic patientsSource: JAMA
Area: News
Evaluation of outcomes in a large multi-national registry of people with atherosclerosis suggests that a number of simple descriptors can identify those at greatest risk of cardiovascular events.
It is often difficult to identify which patients are at the highest risk for cardiovascular events, although being able to do this would be of great value to both practising clinicians and to those carrying out clinical trials. Prior ischaemic events, polyvascular disease, and diabetes have all been identified as predictors of ischaemic events, but their comparative contributions to future risk remain unclear. The authors of this paper used data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry to examine the contribution to overall ri...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Review: Balancing risk and benefit of coronary revascularisation in patients with diabetesSource: Heart
Area: News
This review addresses two important clinical questions about revascularisation in patients with diabetes:
1. In medically-treated non-ACS patients, should revascularisation (CABG or PCI) be offered initially or should it be delayed?
2. When does CABG offer benefits over PCI?
The following topics are discussed:
. Revascularisation versus medical therapy in diabetes
. Bypass Angioplasty Revascularisation Investigation 2 Diabetes trial (BARI 2D) main findings
. Limitations of BARI 2D
. CABG versus PCI in diabetes
. Ongoing study of CABG versus PCI in diabetes
. Clinical implications for patients with diabetes
. Patient involvement
. Advances in medical and surgical ther...Review: Saxagliptin for type 2 diabetes mellitusSource: American Journal of Health-System Pharmacy
Area: News
This review: on saxagliptin, a dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes mellitus examines its pharmacology, pharmacokinetics, efficacy, safety, and dosage and administration. (Source: NeLM - News)Annual Evidence Updates planned for September 2010Source: NHS Evidence
Area: News
NHS Evidence has announced the following Annual Evidence Updates planned for September 2010:
6 September
Epilepsy
Gastrointestinal symptoms in supportive and palliative care
13 September
Alzheimer's disease and dementia
Diabetic Retinopathy
Eczema
20 September
Osteoarthritis
Surgical aspects of faecal incontinence
27 September
Amblyopia
Antenatal and pregnancy care (Source: NeLM - News)Pneumomediastinum as a complication of emphysematous cholecystitis: case reportConclusion:
Emphysematous cholecystitis should be considered as a possible cause of pneumomediastinum. (Source: BMC Gastroenterology)Proposed Diabetes Test Misses Most Cases: StudyA new proposed diabetes test could miss millions of cases of diabetes and pre-diabetes and also over-diagnose black Americans, suggests a new study published online July 16th in Diabetes Care. Reuters Health Information (Source: Medscape Pathology Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Previous gestational diabetes impairs long-term endothelial function in a mouse model of complicated pregnancyWomen who develop gestational diabetes mellitis (GDM) display endothelial dysfunction up to 1 yr after pregnancy, despite a return to normoglycemia. It is unknown whether this dysfunction was preexisting or whether GDM pregnancy leads to long-term endothelial dysfunction. A mouse model that spontaneously develops GDM (Leprdb/+) was used to determine whether the endothelial dysfunction that develops during GDM is evident in later life. Heterozygous and wild-type (WT) controls were allowed to litter once, then age to 9–10 mo, and were compared with virgin controls. Vascular function of small mesenteric arteries was assessed using wire myography. Concentration response curves to the thromboxane A2mimetic U46619 and the endothelium-dependent vasodilator methacholine were constructed. Sup...Metabolic profiling of muscle contraction in lean compared with obese rodentsInterest in the pathophysiological relevance of intramuscular triacylglycerol (IMTG) accumulation has grown from numerous studies reporting that abnormally high glycerolipid levels in tissues of obese and diabetic subjects correlate negatively with glucose tolerance. Here, we used a hindlimb perfusion model to examine the impact of obesity and elevated IMTG levels on contraction-induced changes in skeletal muscle fuel metabolism. Comprehensive lipid profiling was performed on gastrocnemius muscles harvested from lean and obese Zucker rats immediately and 25 min after 15 min of one-legged electrically stimulated contraction compared with the contralateral control (rested) limbs. Predictably, IMTG content was grossly elevated in control muscles from obese rats compared with their lean counte...Maternal obesity and fetal metabolic programming: a fertile epigenetic soilThe incidence of obesity and overweight has reached epidemic levels in the United States and developed countries worldwide. Even more alarming is the increasing prevalence of metabolic diseases in younger children and adolescents. Infants born to obese, overweight, and diabetic mothers (even when normal weight) have increased adiposity and are at increased risk of later metabolic disease. In addition to maternal glucose, hyperlipidemia and inflammation may contribute to the childhood obesity epidemic through fetal metabolic programming, the mechanisms of which are not well understood. Pregravid obesity, when combined with normal changes in maternal metabolism, may magnify increases in inflammation and blood lipids, which can have profound effects on the developing embryo and the fetus in u...Diabetes drug may keep lung cancer at bayCHICAGO (Reuters) - The common diabetes drug metformin may hold promise as a way to keep smokers from developing lung cancer, U.S. researchers said on Wednesday. (Source: Reuters: Health)New Evidence That Fat Cells Are Not Just Dormant Storage Depots for CaloriesSeptember 1, 2010 (EurekAlert) - Scientists are reporting new evidence that the fat tissue in those spare tires and lower belly pooches ? far from being a dormant storage depot for surplus calories ? is an active organ that sends chemical signals to other parts of the body, perhaps increasing the risk of heart attacks, cancer, and other diseases.
read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>New Study Singles out Factors Linked to Cognitive Deficits in Type 2 DiabetesSeptember 1, 2010 (EurekAlert) - Older adults with diabetes who have high blood pressure, walk slowly or lose their balance, or believe they're in bad health, are significantly more likely to have weaker memory and slower, more rigid cognitive processing than those without these problems, according to a new study published by the American Psychological Association.
read more (Source: Diabetes News from dLife.com)Immune System Research Sees Many Similarities Among PeopleFindings may lead to better diagnosis, treatment of cancers, autoimmune diseases, study says (Source: The Doctors Lounge - Neurology)Diabetes drug shows potential as a cancer fighterAn inexpensive drug that's already used to treat type 2 diabetes could find new life as a cancer fighter, with two new studies suggesting it fights off colon cancer and even prevents lung cancer in smokers. (Source: CTV Health)Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in MiceFindings reflect those of population studies in humans, researchers say
Source: HealthDay
Related MedlinePlus Pages: Diabetes Medicines, Lung Cancer (Source: MedlinePlus Health News)Charcot neuroarthropathy: An often overlooked complication of diabetesIn patients with long-standing, poorly controlled diabetes and peripheral neuropathy, a red, hot, swollen foot without open ulceration should raise the suspicion of Charcot neuroarthropathy, an often-overlooked diabetic foot complication. The authors discuss key diagnostic features and how to differentiate this condition from cellulitis, osteomyelitis, and other conditions. They review key elements of the workup and emphasize the importance of early diagnosis and prompt treatment to preserve a functioning foot. (Source: Cleveland Clinic Journal of Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Hospitalized Patients With 2009 H1N1 Influenza Infection: The Mayo Clinic ExperienceCONCLUSION: Hospitalized adults with H1N1 influenza infection are relatively young, and a significant number require treatment in the ICU. Among the patients who require ICU admission, most develop acute lung injury or acute respiratory distress syndrome and require mechanical ventilator support. (Source: Mayo Clinic Proceedings)Impact of Prevalent Fractures on Quality of Life: Baseline Results From the Global Longitudinal Study of Osteoporosis in WomenCONCLUSION: Previous fractures at a variety of bone locations, particularly spine, hip, and upper leg, or involving more than 1 location are associated with significant reductions in quality of life. (Source: Mayo Clinic Proceedings)Balanced diet cuts heart riskConclusion
This well-conducted trial benefits from its relatively large size, accurate provision of the three randomised diets and high study completion rates (95%). It also featured a reliable study outcome by using the average of a series of blood pressure measures, which is preferable to relying on a single blood pressure reading.
The study found that eight weeks of the DASH diet, which was rich in fruit and vegetables and low in saturated fat, lowered blood pressure and cholesterol. This contributed to a decrease in predicted 10-year CHD risk. The DASH diet reduced this risk by 18% compared to a high-saturated fat ?American? diet and by 11% compared to a diet similar to the American diet but with higher intake of fruit and vegetables.
Some points to note when interpreting this stud...Diabetes drug can reduce risk of cancer, researchers findA growing body of evidence suggests that the widely used diabetes drug metformin can reduce the risk of cancer, researchers said Wednesday.
A study in mice exposed to tobacco carcinogens shows that the drug can reduce the development of lung tumors by... (Source: OrlandoSentinel: Medical Research)Death risk from insomnia unclearConclusion
This study has found that in middle-aged men, self-reported insomnia and objectively measured short sleep duration was associated with a greater risk of death during the 14-year follow-up period, compared with men who did not have insomnia or short sleep duration. However, these findings require careful interpretation and do not prove that insomnia increases the risk of early death:
The study has an important limitation in that it is a secondary analysis of a study set up to assess the age distribution of people with sleep-disordered breathing. As such, the participants were not selected at random. All of them had a higher risk of sleep-disordered breathing, and the women had markedly higher BMIs. These factors may affect both mortality risk and insomnia. Therefore, the resul...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Less is More: Study Shows That Teens Who Sleep Less Eat More Fatty Foods and SnacksSeptember 1, 2010 (EurekAlert) - A study in the Sept. 1 issue of the journal Sleep shows that teens who slept less than eight hours per weeknight ate higher proportions of fatty foods and snacks than adolescents who slept eight hours or more. The results suggest that short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance, especially in girls.
read more (Source: Diabetes News from dLife.com)GI Dynamics Announces Distribution Agreement with Elemental Healthcare for the EndoBarrier Gastrointestinal LinerLEXINGTON, Mass. & HUNGERFORD, England--(Healthcare Sales & Marketing Network)--GI Dynamics, a leader in non-surgical, endoscopic treatments for type 2 diabetes and obesity, today announced it has entered into a new agreement with Elemental Healthcare, bas... Devices, DistributionGI Dynamics, Elemental Healthcare, EndoBarrier (Source: HSMN NewsFeed)Association of Interleukin-10 Polymorphisms with Cytokines in Type 2 Diabetic NephropathyDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)The Fallacy of Hindsight: Response to Moses and KoenenDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)Lower Rate of Initial Failures and Reduced Occurrence of Adverse Events with a New Catheter Model for Continuous Subcutaneous Insulin Infusion: Prospective, Two-Period, Observational, Multicenter StudyDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Analysis of Hemodialysis-Associated Hypoglycemia in Patients with Type 2 Diabetes Using a Continuous Glucose Monitoring SystemDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)Detrended Fluctuation Analysis Is Considered to Be Useful as a New Indicator for Short-Term Glucose ComplexityDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)Inter-Day Glycemic Variability Assessed by Continuous Glucose Monitoring in Insulin-Treated Type 2 Diabetes Patients on HemodialysisDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)MIF knockdown impairs glucose homeostasisMacrophage migration inhibitory factor (MIF) is a cytokine which affects carbohydrate metabolism and has been linked to obesity and insulin resistance. Serre-Beinier and colleagues have shown that MIF plays an active role in insulin secretion and glucose homeostasis for the first time, using MIF knockout mice. MIF deficiency affected body weight gain; mice had a lower body weight at birth, whilst after birth a higher body weight gain was observed compared to wild type mice, due to increased food intake. Older mice without the MIF gene had impaired glucose tolerance, with an age-dependent increase in fasting insulin levels being observed. This leads to an increase in glucose uptake which may explain the increased fat mass of older mice.
Whilst further work needs to be done to elucidate MIF&...Diabetes-Related Risk Factors and Cognitive AgingFocus on Obesity, Insulin Resistance, and the Metabolic Syndrome (Source: Psychiatric Times)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Whisky from the Urine of DiabeticsI learned of whisky made from the urine of diabetics while reading Slashdot today. Sugar is recovered from the urine of a diabetic person and is added to the whisky ...Read Full Post (Source: About.com Chemistry)Improving Ocular Disease Screening By LED Illumination Of The EyeA new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics... (Source: Health News from Medical News Today)Differences in cortical and pituitary activity in response to hypoglycaemia and cognitive testing in healthy men with different basal activity of the renin-angiotensin systemConclusion. Basal RAS activity influenced cerebral activity. Low RAS was associated with more pronounced cortical activation in all glycaemic conditions. High RAS was associated with pituitary activation during hypoglycaemia and post-hypoglycaemia, and this was associated with a greater growth hormone response. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)Spironolactone ameliorates podocytic adhesive capacity via restoring integrin {alpha}3 expression in streptozotocin-induced diabetic ratsPodocyte responses to various injuries include detachment from the glomerular basement membrane (GBM) with impaired adhesion ability. Growing evidence suggests inappropriately enhanced aldosterone levels in glomeruli may contribute to podocytic injury and subsequently glomerulosclerosis in diabetic nephropathy (DN). In the present study, we aimed to investigate podocytic integrin 3 expression and urinary podocyte excretion in streptozotocin (STZ)-induced diabetic rats, and to evaluate their responses to spironolactone (SPL). STZ-induced male diabetic Wistar rats were treated with vehicle (the STZ group, n=7), or spironolactone (the STZ+SPL group, n=6) for 12 weeks, six additional rats of similar body weight serving as control. Urine specimens were obtained for measurement of urine albumin ...ORIGINAL ARTICLE: Differences in mouse models of diabetes mellitus in studies of male reproductionSummary (Source: International Journal of Andrology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Insomnia with Short Sleep Duration and Mortality: The Penn State CohortConclusions: Insomnia with objective short sleep duration in men is associated with increased mortality, a risk that has been underestimated.
Keywords: Insomnia, short sleep duration, mortality, population-based study (Source: Sleep)Comparison of family partnership intervention care vs. conventional care in adult patients with poorly controlled type 2 diabetes in a community hospital: A randomized controlled trialThis study aimed to compare FPIC with conventional care (CC) across a number of outcome measures in patients with poorly controlled type 2 diabetes.Design: The study was performed using a randomized controlled trial design.Participants: Patients with poorly controlled type 2 diabetes who were solely treated with oral antidiabetic agents and had at least two out of three hemoglobin A1C readings equal to or above 7% in the previous 12 months, were randomly assigned to the FPIC group (n=28) and to the CC group (n=28).Methods: Baseline and 6-month follow-up scores were compared using the following outcome measures: (1) hemoglobin A1C, (2) BMI, (3) lipid profile, (4) family supportive behaviours, (5), knowledge of and attitudes toward diabetes, and (6) diabetes self-care behaviours. Descriptive...Crisps: a very British habitThey're fried in fat and smothered in salt, but still we eat a heart-stopping 6bn packets of them a year. So why do we have an unhealthy obsession with potato crisps?? Food blog: what's your favourite crisp?In an unremarkable suburb of Leicester called Beaumont Leys is a big factory ? or actually two, side by side. But let's not split hairs already. The point is that it's big; a winding 10-minute march from reception round to the delivery bays.These bays are where the raw material comes in, which is potatoes. The variety changes with the season, depending on whether they've come straight from the fields in summer, or from storage during winter. There are Hermes, Saturna and, right now, round, pink-cheeked Lady Rosetta.Let's follow her, briefly. She is washed out of the truck ? sheddi...Retinal DetachmentTitle: Retinal DetachmentCategory: Diseases and ConditionsCreated: 3/8/2000Last Editorial Review: 9/1/2010 (Source: MedicineNet Diabetes General)Eicosapentaenoic acid as an add-on to antidepressant medication for co-morbid major depression in patients with diabetes mellitus: A randomized, double-blind placebo-controlled studyAbstract: Background: Depression is common in individuals with diabetes. The present study is the first randomized controlled trial to test the efficacy of ?-3 ethyl-eicosapentaenoic acid (E-EPA) as adjuvant to antidepressant medication in the treatment of depression in adults with diabetes mellitus.Methods: In the VU University Medical Center, we conducted a 12-week, placebo-controlled, double-blind, parallel-group intervention study of E-EPA (1g/day) versus placebo in 25 diabetes patients meeting DSM-IV criteria for major depressive disorder, who were already using antidepressant medication. The primary outcome was severity of depressive symptoms, assessed by the Montgomery Åsberg Depression Rating Scale (MADRS) at baseline and 12-week follow-up at two-weekly intervals. Blood samples w...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Behind the headlines - Genetic effects of vitamin D studied?Stocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,? reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di...Behind the headlines - Genetic effects of vitamin D studied?Stocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,? reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di...Diabetes may speed up progression of mild cognitive impairmentThe presence of diabetes in patients with mild cognitive impairment can accelerate progression to dementia by more than 3 years, a Swedish study suggests. (Source: MedWire News - Diabetes)Behind the headlines - Genetic effects of vitamin D studied?Stocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,? reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di...Study finds an increased risk of death in men with insomnia and a short sleep duration(American Academy of Sleep Medicine) Men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>New study singles out factors linked to cognitive deficits in type 2 diabetes(American Psychological Association) Older adults with diabetes who have high blood pressure, walk slowly or lose their balance, or believe they're in bad health, are significantly more likely to have weaker memory and slower, more rigid cognitive processing than those without these problems, according to a new study published by the American Psychological Association. (Source: EurekAlert! - Medicine and Health)JCI online early table of contents: Sept. 1, 2010(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Sept. 1, 2010, in the JCI: "Protecting nerve cells from death in a model of stroke"; "Modified adenovirus malaria vaccine works a treat in mice"; "Mechanisms of testicular cancer drug resistance"; "Pacifying protein levels to treat diabetes"; "Preemptive approach to decreasing scarring in the heart"; and others. (Source: EurekAlert! - Cancer)Continuous Glucose Monitoring Reveals Delayed Nocturnal Hypoglycemia After Intermittent High-Intensity Exercise in Nontrained Patients with Type 1 DiabetesDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)Effective Intervention or Child's Play? A Review of Video Games for Diabetes EducationDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)Use of Insulin Pumps in India: Suggested Guidelines Based on Experience and Cultural DifferencesDiabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>University opens £600k unit to help fight against diabetesA NEW £600,000 research facility at Perth Royal Infirmary, funded by the Dundee University's Diabetes Research Campaign, was officially opened yesterday by broadcaster Fre (Source: Scotsman.com News - Health)Breastfeeding may lower diabetes risk in mothersMothers who breastfeed their children for at least 1 month may have a lower risk for diabetes than those who breastfeed for less time or do not breast feed at all, US researchers report. (Source: MedWire News - Diabetes)Adding Alogliptin to Pioglitazone Is Effective First-Line Option for Type 2 DiabetesThe combination of the dipeptidyl peptidase (DPP)-4 inhibitor alogliptin and the thiazolidinedione pioglitazone reduces HbA1c when type 2 diabetes isn't controlled by diet and exercise, a randomized study has shown. Reuters Health Information (Source: Medscape Diabetes Headlines)Beyond statin therapy: a review of the management of residual risk in diabetes mellitusThis article will review dyslipidaemia and its role in DM, and will discuss available treatment modalities that address residual cardiovascular risk in this disease. (Source: JRSM)Predictors of direct costs of diabetes care in pediatric patients with type 1 diabetes(Source: Pediatric Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Improving diabetes care in a public hospital medical clinic: report of a completed audit cycle(Source: Journal of Evaluation in Clinical Practice)AAFP-CIHI10 Global Burden of Chronic Disease (Edward Shahady MD)Chronic diseases including cardiovascular disease, diabetes, and cancer, are the leading cause of death and disability in both the developed and developing world (excluding sub-Saharan Africa). Developing countries face the triple menace of trauma, infectious/communicable diseases and the increasing burden of non-communicable/chronic diseases like diabetes and cardiovascular disease and cancer. Urbanization, lifestyle changes and aging of populations contribute to the epidemic of chronic disease. Prolonged exposure to risk factors increases the probability of chronic disease development. Strategies that are within the resources of a country are needed to address this epidemic. This session will discuss the prevalence of global chronic disease and strategies like the poly pill care and othe...Pregnancy: A Screening Test for Later Life Cardiovascular DiseaseCardiovascular disease is the major cause of death in women. Heart disease presents special problems to women, as first events are more likely to be fatal. These observations have led to attempts to increase recognition of risk for the disease by care providers and women and to identify women at risk. In 2007, the American Heart Association updated their Evidence Based Guidelines for Cardiovascular Disease Prevention in Women (). In it, they presented guidelines for evaluating risk for cardiovascular disease in women. Interestingly, in the text, tables, and flow charts there is no mention of obtaining a pregnancy history. In the text there is mention: ?preeclampsia may be an early indicator of CVD risk.? In this presentation, we point out there is no doubt that preeclampsia is associat...Self-Reported Delays in Receipt of Health Care among Women with Diabetes and Cardiovascular ConditionsConclusion: Women are more likely to experience delays in health care, even after adjusting for health coverage. Efforts are needed to understand factors that influence gender differences in these delays and to determine whether policy reforms eliminate or exacerbate these differences. (Source: Womens Health Issues)Racial/Ethnic Disparities in Gestational Diabetes Mellitus: Findings from a Population-Based SurveyConclusion: Non-Hispanic API women, especially Asian women with both normal and high BMI, have increased risk of GDM. Future research should examine the unique risk factors experienced by Asians and health practitioners should be vigilant in screening for GDM regardless of BMI. (Source: Womens Health Issues)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Impact of early psychosocial factors (childhood socioeconomic factors and adversities) on future risk of type 2 diabetes, metabolic disturbances and obesity: a systematic reviewConclusions:
Taken together, there is evidence that childhood SES is associated with type 2 diabetes and obesity in later life. The database on the role of psychological factors such as traumata and childhood adversities for the future risk of type 2 diabetes or obesity is too small to draw conclusions. Thus, more population-based longitudinal studies and international standards to assess psychosocial factors are needed to clarify the mechanisms leading to the observed health disparities. (Source: BMC Public Health - Latest articles)Serum transforming growth factor ?1 during diabetes development in non?obese diabetic mice and humans(Source: Clinical and Experimental Immunology)Original Paper: Telmisartan Effects on Insulin Resistance in Obese or Overweight Adults Without Diabetes or HypertensionJ Clin Hypertens (Greenwich). 2010;12:746?752. © (Source: The Journal of Clinical Hypertension)Is antidepressive use associated with increased risk of diabetes?Source: Diabetes Care
Area: News
Follow-up of participants in a diabetes prevention study found an association between continuous use of antidepressive drugs and increased risk of overt diabetes in a high-risk population.
The Diabetes Prevention Program (DPP) examined whether lifestyle change or metformin treatment affected the risk of developing diabetes in a high-risk population: the study was stopped when it showed that both active interventions were more effective than placebo and consenting participants were followed-up in the Diabetes Prevention Program Outcomes Study (DPPOS). An earlier report from the Program noted an association between antidepressive drug use and development of diabetes, and this paper reports an assessment of the association after ten years follow-up...FDA grants priority review of fluocinolone acetonide (IluvienT) for diabetic macular oedemaSource: BioSpace
Area: News
Biospace has reported that the U.S. Food and Drug Administration (FDA) has granted fluocinolone acetonide intravitreal insert (IlluvienT) Priority Review status for the treatment of diabetic macular oedema.
Iluvien is a sustained drug delivery system that releases sub-microgram levels of fluocinolone acetonide and is currently being investigated in two global Phase 3 pivotal clinical trials (collectively known as the FAME Study) involving 956 patients (Source: NeLM - News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Contents(Source: Journal of Diabetes and Its Complications)Fatty Liver Linked to Insulin Resistance in Obese TeensIn obese adolescents, fatty liver -- independent of visceral fat and intramyocellular lipid content --
is associated with impaired insulin activity in the muscles and liver; along with other findings, this suggests the
liver plays a key role in insulin resistance in these individuals, according to research published in the August
issue of Diabetes Care. (Source: Modern Medicine)Growth Factor Inhibition May Help Diabetes PatientsInhibiting transforming growth factor-β1 expression in CD34+ cells may prove therapeutic
for patients with type 2 diabetes by increasing the cells' vascular repair ability, according to research published
in the August issue of Diabetes. (Source: Modern Medicine)Sibutramine May Raise Risks in Those With CVD, DiabetesIn overweight or obese subjects with cardiovascular disease and diabetes, long-term use of sibutramine
is associated with an increased risk of nonfatal myocardial infarction and nonfatal stroke but not cardiovascular
death or any-cause death, according to a study in the Sept. 2 issue of the New England Journal of
Medicine. (Source: Modern Medicine)The Development of a Pressure Ulcer Risk-Assessment Scale for Perioperative PatientsAbstract: The high incidence of pressure ulcer development in patients in the perioperative setting indicates the need for improved risk assessment and the use of preventive measures. A clinical nurse specialist used Dever's Epidemiological Model as the theoretical framework to develop a perioperative pressure ulcer risk-assessment scale. The risk factors for the scale were based on findings from a review of the literature. The scale, along with a demographic questionnaire and an evaluation form, was distributed to 12 nurses and three anesthesiologists to obtain expert opinion to further the design of the scale. Twelve participants returned the forms. Only four of the participants had previous experience with a pressure ulcer risk-assessment scale. The results indicated that diabetes shoul...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Diet and weight gain characteristics of pregnant women with gestational diabetesAuthors: M Salmenhaara, L Uusitalo, U Uusitalo, C Kronberg-Kippilä, H Sinkko, S Ahonen, R Veijola, M Knip, M Kaila
& S M Virtanen (Source: European Journal of Clinical Nutrition)Microplasmin for Vitreomacular TractionWe congratulate de Smet et al. on their article about microplasmin in patients with vitreomacular traction before vitrectomy. In previous publications we have reported our results with autologous plasmin enzyme (APE) in diabetic macular edema, macular epiretinal membranes (MEM), and vitreomacular traction syndromes (VMTS). We continue our research in patients with various causes of macular edema where the vitreous is attached to the retina, and this seems to be the cause of the persistence of the edema or its worsening. (Source: Ophthalmology)Traffic Trouble: Study Links Diabetes to Vehicular Pollution(Source: EHP-in-Press)The association between the spatial QRS?T angle with cardiac autonomic neuropathy in subjects with Type?2 diabetes mellitus(Source: Diabetic Medicine)Predictors of incident major depression in diabetic outpatients with subthreshold depression(Source: Diabetic Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>The effect of diabetes mellitus on age?associated lean mass loss in 3153 older adults(Source: Diabetic Medicine)An exploration of knowledge and attitudes related to pre?pregnancy care in women with diabetes(Source: Diabetic Medicine)N?terminal fragment of pro?brain natriuretic peptide (NT?proBNP) for predicting silent myocardial ischaemia in type 2 diabetes mellitus independent of microalbuminuria(Source: Diabetes/Metabolism Research and Reviews)A novel biphenyl compound, VMNS2e, ameliorates streptozotocin induced diabetic nephropathy in rats(Source: Journal of Diabetes)Obesity and diabetes genetic variants associated with gestational weight gainConclusion: We found evidence that diabetes and obesity risk alleles interact with maternal pregravid body mass index to predict gestational weight gain. (Source: American Journal of Obstetrics and Gynecology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>BASIC SCIENCE RESEARCH?Original Articles: Effects of Diabetes Mellitus on VEGF?Induced Proliferation Response in Bone Marrow Derived Endothelial Progenitor CellsAbstract (Source: Journal of Cardiac Surgery)Stem cell approaches for the treatment of type 1 diabetes mellitus.This article reviews the different approaches that are being taken to produce new b cells. Much emphasis has been placed on selecting the right non-b cell population, either in vivo or in vitro, as the starting material. Different cell types, including adult stem cells, other types of progenitor cells in situ, and even differentiated cell populations, as well as embryonic stem cells and induced pluripotent stem cells, will require different methods for islet and b cell induction. We discussed the pros and cons of the different strategies that are being used to re-invent the pancreatic b cell.
PMID: 20801414 [PubMed - as supplied by publisher] (Source: Translational Research : the journal of laboratory and clinical medicine)Alkem Lab develops low-cost sweetenerAlkem Laboratories has developed a low-cost sweetener that can be a game changer in the market which houses the most number of diabetes patients in the world. (Source: The Economic Times Healthcare and Biotech News)Alkem Lab develops low-cost sweetenerAlkem Laboratories has developed a low-cost sweetener that can be a game changer in the market which houses the most number of diabetes patients in the world. (Source: The Economic Times Healthcare and Biotech News)High-Fat Diet During Puberty Linked to Breast Cancer Risk Later in LifeAugust 31, 2010 (EurekAlert) - Girls eating a high-fat diet during puberty, even those who do not become overweight or obese, may be at a greater risk of developing breast cancer later in life, according to Michigan State University researchers.
The implications - that a high-fat diet may have detrimental effects independent of its effect to cause obesity - could drive new cancer prevention efforts.
read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Obesity, Diabetes Epidemics Continue to Grow in California, UCLA Study FindsAugust 31, 2010 (EurekAlert) - A majority of adults in California are obese or overweight, and more than 2 million have been diagnosed with diabetes, according to a new study from the UCLA Center for Health Policy Research.
Both conditions ? which are related to each other as well as to heart disease ? increased significantly in just six years, with the prevalence of diabetes alone jumping nearly 26 percent between 2001 and 2007.
read more (Source: Diabetes News from dLife.com)LEDs Illuminate Eye for Ocular Disease ScreeningAugust 31, 2010 (EurekAlert) - A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics.
read more (Source: Diabetes News from dLife.com)Scientists Discover New Protein That Gets to the Roots of Obesity and OsteoporosisAugust 31, 2010 (EurekAlert) - Here's good news for anyone trying to lose weight or has osteoporosis: Scientists from Maine are on the trail of a weight loss drug that may revolutionize how we treat these two conditions. In a new research report published in the September 2010 print issue of The FASEB Journal, the researchers describe a newly discovered protein, called "Sprouty," responsible for regulating body fat and bone mass.
read more (Source: Diabetes News from dLife.com)Humanized nonobese diabetic-scid IL2r{gamma}null mice are susceptible to lethal Salmonella Typhi infection [Microbiology]Salmonella enterica serovar Typhi, the cause of typhoid fever, is host-adapted to humans and unable to cause disease in mice.... (Source: Proceedings of the National Academy of Sciences)
2 is the far more common version of the disease. Up to 90% or more of all sufferers have this version of the disease. The body develops a complex resistance to insulin. Insulin in the body is used to control blood sugar. When the body produces insulin, the blood sugar in the body is lowered. In this way, insulin regulates the energy you receive from blood sugar (glucose) as well as monitoring the level naturally. With an insulin resistance, the body does not regulate itself as well. Blood sugar levels become higher than normal due to this. Type 2 can be passed from generation to generation and is often found in overweight people or those with very bad diets. However, there are skinny and healthy people who suffer from this version of as well. What you eat can play a big factor with type 2 diabetes. If you catch it before it's too late, you can even reverse the trend in your body. Taking out carbohydrates, which are broken down into sugar, is one step. Another step you can take is eating smaller meals more frequently, as opposed to larger meals just two or three times a day. The most important step you can take however is to be informed. You need to get your blood sugar tested and evaluated. This is particularly true if you have a family history or if you notice other symptoms. Symptoms are wide ranging and could include lethargy, or in men, erectile dysfunction. Type 2 can be controlled effectively in most cases without the need for insulin shots. Staying informed and living a healthy lifestyle with diet and exercise is the best thing you can do to prevent the onset of diabetes, and to battle it once you are diagnosed.
Here are some more diabetes articles...
Infectious And Non-infectious Causes Of Sinusitis - Part One
By Groshan Fabiola
On a predisposed field for infection, like a cold or a flu causing virus, sinuses disorders are usually caused by bacterial organisms. Sinusitis is mostly an acute case and can be well treated; in Read more...
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Carbohydtrates In Your Cooking
By dr_chef
The major function of carbohydrates is to provide energy for muscular activity and the creation of warmth. The greater the physical demands on the body, the higher is the energy need and, therefore, Read more...
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Recipes for Health: Grilled Mushrooms in Foil Packets
Prepare these packets at home, then toss them on the grill at a cookout. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Beat Breakfast Boredom with 5 New Ways to Jazz Up Cereal
Day after day (and bowl after bowl), the idea of the same old cereal gets a little soggy. So, to jazz up your old reliable cereal plus low-fat milk combo, we've poured out a few new breakfast options for you to crunch on. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Jewel-Osco 2010 Hunger Relief Grant Program
Funding designed to fund the operational needs of food pantries and soup kitchens. Geographic coverage: Illinois and Indiana -- (Source: Food and hunger funding opportunities via the Rural Assistance Center)
Foot Pain
Title: Foot PainCategory: Diseases and ConditionsCreated: 5/13/2008Last Editorial Review: 9/1/2010 (Source: MedicineNet Digestion General)
Enterovirulent E. Coli (EEC)
Title: Enterovirulent E. Coli (EEC)Category: Diseases and ConditionsCreated: 7/3/1998Last Editorial Review: 9/1/2010 (Source: MedicineNet Digestion General)
Recipes for Health: Turkish Bean and Herb Salad
This fragrant bean salad requires far less olive oil than the traditional version. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Contents ? Molecular Nutrition Food Research 9'2010
(Source: Nahrung / Food)
Editorial Board: Mol. Nutr. Food Res.
(Source: Nahrung / Food)
Cover Picture: Mol. Nutr. Food Res. 9'2010
Abstract (Source: Nahrung / Food)
Vitamin A status of healthy children in Manisa, Turkey
Conclusions:
This study showed that VAD is a moderate health problem in Manisa. (Source: Nutrition Journal)
The effects of phytosterols present in natural food matrices on cholesterol metabolism and LDL-cholesterol: a controlled feeding trial
Authors: X Lin, S B Racette, M Lefevre, C A Spearie, M Most, L Ma
& R E Ostlund (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Penetration of nutrition information on food labels across the EU-27 plus Turkey
Authors: S Storcksdieck genannt Bonsmann, L Fernández Celemín, A Larrañaga, S Egger, J M Wills, C Hodgkins
& M M Raats (Source: European Journal of Clinical Nutrition)
Environmental contaminants as biomarkers of fish intake: a case for hair mercury concentrations
European Journal of Clinical Nutrition advance online publication, September 1, 2010. doi:10.1038/ejcn.2010.177
Author: J G Dórea (Source: European Journal of Clinical Nutrition)
Should waist circumference be used to identify metabolic disorders than BMI in South Korea?
Should waist circumference be used to identify metabolic disorders than BMI in South Korea?
European Journal of Clinical Nutrition advance online publication, September 1, 2010. doi:10.1038/ejcn.2010.175
Author: S-K Lee (Source: European Journal of Clinical Nutrition)
Neighbourhood-socioeconomic variation in women's diet: the role of nutrition environments
Authors: L E Thornton, D A Crawford
& K Ball (Source: European Journal of Clinical Nutrition)
Development of a lifestyle?diet quality index for primary schoolchildren and its relation to insulin resistance: the Healthy Lifestyle?Diet Index
Development of a lifestyle–diet quality index for primary schoolchildren and its relation to insulin resistance: the Healthy Lifestyle–Diet Index
European Journal of Clinical Nutrition advance online publication, September 1, 2010. doi:10.1038/ejcn.2010.172
Authors: Y Manios, G Kourlaba, E Grammatikaki, A Koubitski, P-E Siatitsa, A Vandorou, K Kyriakou, V Dede
& G Moschonis (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Role of physical activity and diet in incidence of hypertension: a population-based study in Portuguese adults
Authors: M Camões, A Oliveira, M Pereira, M Severo
& C Lopes (Source: European Journal of Clinical Nutrition)
Comparison of two methods for identifying dietary patterns associated with obesity in preschool children: the GENESIS study
Authors: Y Manios, G Kourlaba, E Grammatikaki, O Androutsos, E Ioannou
& E Roma-Giannikou (Source: European Journal of Clinical Nutrition)
Diet and weight gain characteristics of pregnant women with gestational diabetes
Authors: M Salmenhaara, L Uusitalo, U Uusitalo, C Kronberg-Kippilä, H Sinkko, S Ahonen, R Veijola, M Knip, M Kaila
& S M Virtanen (Source: European Journal of Clinical Nutrition)
Effects of a sphingolipid-enriched dairy formulation on postprandial lipid concentrations
Authors: L Ohlsson, H Burling, R-D Duan
& Å Nilsson (Source: European Journal of Clinical Nutrition)
The transcobalamin (TCN2) 776C>G polymorphism affects homocysteine concentrations among subjects with low vitamin B12 status
The transcobalamin (TCN2) 776C>G polymorphism affects homocysteine concentrations among subjects with low vitamin B12 status
European Journal of Clinical Nutrition advance online publication, September 1, 2010. doi:10.1038/ejcn.2010.157
Authors: A Stanisławska-Sachadyn, J V Woodside, C M Sayers, J W Yarnell, I S Young, A E Evans, L E Mitchell
& A S Whitehead (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
School lunch and learning behaviour in primary schools: an intervention study
Authors: R Golley, E Baines, P Bassett, L Wood, J Pearce
& M Nelson (Source: European Journal of Clinical Nutrition)
Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves' disease?
Context: Hyperthyroidism can lead to reduced bone mineral density (BMD) and increased fracture risk particularly in postmenopausal women, but the mechanism behind is still unclear.ObjectiveProspective examination of the influence of thyroid hormones and/or thyroid autoantibodies on BMD in premenopause.DesignWe have examined 32 premenopausal women with untreated active Graves' disease from time of diagnosis, during 18 months of antithyroid drug therapy (ATD) and additionally 18 months after discontinuing ATD. Variables of thyroid metabolism, calcium homeostasis and body composition were measured every 3 months. BMD of lumbar spine and femoral neck were measured at baseline, 18+/-3 and 36+/-3 months. Data were compared to base line, a sex- and age matched control group and a group of patient...
Recipes for Health: Creamy Potato Salad With Yogurt Vinaigrette
This dish may resemble a traditional potato salad, but it does not rely on mayonnaise. (Source: NYT)
Really?: The Claim: Flying After Breast Cancer Surgery Can Cause Swelling
Lymph nodes are often removed as treatment. The concern is that changes in cabin pressure might influence the movement of fluid in the lymphatic system. (Source: NYT)
Making Soldiers Fit to Fight, Without the Situps
The goal of a new training program is to reduce injuries and better prepare recruits for the rigors of combat. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Personal Health: Weight Index Doesn?t Tell the Whole Truth
Body mass index may be useful for identifying obesity in large populations, but in individuals it doesn?t differentiate between fatty and lean tissue. (Source: NYT)
[August 2010 Blogroll] Top Gluten-Free Insider - ATX Gluten-Free
Even though she is obsessed with food and has a nutrition degree, Jessica Meyer struggled for a long time before she was diagnosed with Celiac disease and adopted a gluten-free diet. Jessica's blog includes her original gluten-free recipes, as well as new gluten-free menu options, and product and company information specific to the Austin, Texas local community. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Food Better Than Supplements for Cancer Prevention: Expert
Title: Food Better Than Supplements for Cancer Prevention: ExpertCategory: Health NewsCreated: 8/27/2010 10:10:00 AMLast Editorial Review: 8/30/2010 (Source: MedicineNet Digestion General)
Health Tip: Treating Rotavirus at Home
Title: Health Tip: Treating Rotavirus at HomeCategory: Health NewsCreated: 8/27/2010 10:10:00 AMLast Editorial Review: 8/30/2010 (Source: MedicineNet Digestion General)
How Can I Help My Clients Sort Out the Conflicting and Confusing Information Regarding Dietary Supplements?
Last year's economic downturn didn't slow the sales of dietary supplements. Nutrition Business Journal estimates show that total US consumer sales of dietary supplements expanded to $25.2 billion (). Although many Americans use dietary supplements, a 2009 report from the US Government Accountability Office stated that consumers are not well informed about the safety and efficacy of dietary supplements and have difficulty interpreting labels on these products (). ADA's position paper on Nutrient Supplements states that it is the expertise of the registered dietitian to educate the consumer on safe and appropriate use of dietary supplements (). So where do you start? (Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
September 2010 New Products & Services
(Source: Journal of the American Dietetic Association)
September 2010 Classified Advertisements
(Source: Journal of the American Dietetic Association)
September 2010 People & Events
2010 ADA Food & Nutrition Conference & Expo November 6-9, 2010; Boston, MA (Source: Journal of the American Dietetic Association)
2010-2011 Officers List and Committee Members
The American Dietetic Association (ADA) has announced that the following members will serve as elected officers and committee members for 2010-2011. For more information on an officer whose address or telephone number has not been provided, contact the ADA staff member in that group or access ADA's online Leadership Directory at http://www.eatright.org/Members/leadership.aspx?&C=80003209. (The information on this list was provided to the Journal by various ADA staff members. Questions about this list should be directed to the corresponding ADA staff member.) (Source: Journal of the American Dietetic Association)
Emerging Dietetics Leader Awards, 2010
The Emerging Dietetics Leader Award recognizes the competence and activities of members, regardless of their age, who are at the beginning of their dietetics careers. Members receiving this honor have supported the promotion of optimal health and nutritional status of the public through demonstrating leadership in legislation, research, education, management, and other areas related to the profession. (Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Outstanding Dietitian of the Year, 2010
The American Dietetic Association is honored to recognize the recipients of the affiliate dietetic associations' outstanding dietitian awards. These members have made distinguished contributions to advancing the profession. The criteria and the name of the award are determined by each state organization. (Source: Journal of the American Dietetic Association)
Outstanding Dietetics Educator Awards, 2010
The Outstanding Dietetics Educator Award recognizes the teaching, mentoring, and leadership activities of faculty and preceptors in dietetics education programs that are accredited by the Commission on Accreditation for Dietetics Education. The selection of awardees is determined by the Dietetic Educators of Practitioners Practice Group. (Source: Journal of the American Dietetic Association)
Outstanding Dietetics Student Awards, 2010
The Outstanding Dietetics Student Award encourages participation in the American Dietetic Association by recognizing the emerging leadership and achievement of students in dietetics education programs that are accredited by the Commission on Accreditation for Dietetics Education. States may select one student recipient from each type of education program: Didactic Program in Dietetics, Dietetic Internship, Coordinated Program, and Dietetic Technician Program. (Source: Journal of the American Dietetic Association)
Recognized Dietetic Technicians of the Year, 2010
The American Dietetic Association recognizes the professional contributions of dietetic technicians and encourages their continued participation in the community and Association activities. (Source: Journal of the American Dietetic Association)
Recognized Young Dietitians of the Year, 2010
The American Dietetic Association (ADA) joins with its affiliated dietetic associations from 50 states, the District of Columbia, Puerto Rico, and the American Overseas Dietetic Association to salute the ADA members selected as ?Recognized Young Dietitians of the Year? for 2010. (Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Position of the American Dietetic Association: Food Insecurity in the United States
Abstract: It is the position of the American Dietetic Association that systematic and sustained action is needed to achieve food and nutrition security for all in the United States. To eliminate food insecurity, interventions are needed, including adequate funding for and increased utilization of food and nutrition assistance programs, inclusion of food and nutrition education in such programs, and innovative programs to promote and support individual and household economic self-sufficiency. More than 49 million individuals living in the United States experienced food insecurity in 2008. Negative nutrition and non?nutrition-related outcomes have been associated with food insecurity in children, adolescents, and adults, including substandard academic achievement, inadequate intake of key ...
Involvement of Young Australian Adults in Meal Preparation: Cross-Sectional Associations with Sociodemographic Factors and Diet Quality
Abstract: Involvement in meal preparation has the potential to affect diet quality, but has not been thoroughly investigated. The study aims were to describe the involvement of young adult men and women in meal preparation and to investigate whether extent of involvement was associated with diet quality. During 2004 to 2006, a national sample of 2,814 Australian adults aged 26 to 36 years completed a self-administered questionnaire on demographics, diet, and lifestyle factors. Participants were asked to report who was usually responsible for preparing the main meal on working days. Responses were categorized as ?myself,? ?shared,? or ?someone else.? Diet quality was assessed by calculating the mean number of daily servings for each food group. Analysis of variance was used to t...
Intake of Lutein and Zeaxanthin Differ with Age, Sex, and Ethnicity
Abstract: Lutein and zeaxanthin are carotenoids that are selectively taken up into the macula of the eye, where they may protect against development of age-related macular degeneration. Accurate assessment of their intakes is important in the understanding of their individual roles in eye health. Current dietary databases lack the appropriate information to ascertain valid dietary intakes of these individual nutrients. The purpose of this research is to determine intakes of lutein and zeaxanthin separately in the National Health and Nutrition Examination Survey (NHANES) 2003-2004. The top major food sources for lutein and zeaxanthin intake in NHANES 2003-2004 were analyzed for lutein and zeaxanthin by high-performance liquid chromatography from June to August 2006. Results were applied to ...
Race, Homelessness, and Other Environmental Factors Associated with the Food-Purchasing Behavior of Low-Income Women
Abstract: Observance of the hunger-obesity paradox in urban Minnesota has ignited interest in the quality of low-income households' food purchases. This cross-sectional study investigated low-income, urban Minnesotan women's past-month food purchases and their associations with race, homelessness, and aspects of the food system, including food shelf (ie, food pantry) and food store usage, factors believed to influence food choice and grocery shopping behavior. The survey included demographics, the US Department of Agriculture's 18-item Household Food Security Survey Module, and grocery shopping questions related to food purchases and food stores visited in the past month. Participants were a convenience sample of 448 low-income, urban Minnesotan women, and data were collected from February...
Timely Resolution of Patient Concerns Improves Post-Discharge Satisfaction
Abstract: This research examined the effectiveness of a Food and Nutrition Services (FNS) Patient Advocate program on post-discharge patient satisfaction. All inpatients (n=187) who rated their satisfaction with one or more of six FNS attributes as 3 or lower (on a 5-point scale) during a 4-month time period were visited by the FNS Patient Advocate, as were other patients on the units. A questionnaire similar to the inpatient satisfaction questionnaire was sent post-discharge to patients visited by the FNS Patient Advocate (n=374); a total of 158 (42%) responded. Results indicated that most patients (73%) recalled their interaction with the FNS Patient Advocate and were highly satisfied with their interaction with the Advocate (mean=5.8 on 7-point scale). Comparison of inpatient and post-d...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Dietary Intake Patterns of Low-Income Urban African-American Adolescents
This study aimed to describe dietary patterns including energy, nutrients, food groups, and diet quality and to identify areas to guide future interventions. Baseline data for a school-based obesity prevention study were collected from 382 African-American adolescents (10- to 14-year-olds) from four Chicago, IL, public schools in 2003. Diet was assessed using a 152-item food frequency questionnaire. Diet quality was measured using a modified version of the US Department of Agriculture Healthy Eating Index (HEI) and compared to published estimates for a nationwide sample. Participants reported high energy intakes and several unhealthy eating patterns: 58.6% consumed one or more servings of sweetened beverages per day and 15.7% consumed three or more servings per day; average fried food cons...
The Beneficial Effect of Family Meals on Obesity Differs by Race, Sex, and Household Education: The National Survey of Children's Health, 2003-2004
In conclusion, family meals seem to be protective of obesity in non-Hispanic white children and non-Hispanic black boys, whereas they may put Hispanic boys living in low-education households at risk. Greater emphasis is needed in future research on assessing why this association differs among different race/ethnic groups, and evaluating the influence of the quality and quantity of family meals on child obesity. (Source: Journal of the American Dietetic Association)
Population-Specific Short-Form Mini Nutritional Assessment with Body Mass Index or Calf Circumference Can Predict Risk of Malnutrition in Community-Living or Institutionalized Elderly People in Taiwan
The objectives of this study were to determine whether adoption of population-specific body mass index (BMI) cutpoints would improve the predictive ability of the short-form Mini Nutritional Assessment (MNA) and whether calf circumference could be an acceptable alternative to BMI in the short-form MNA without compromising its predictive ability. Using convenience sampling, the study recruited 301 community-living, 109 care center?living, and 68 nursing home?living elderly people, 65 years or older, as subjects. Subjects were evaluated with the short-form MNA in three versions: (a) the original, (b) Taiwan version 1 (T1), that adopted population-specific BMI cutpoints, and (c) Taiwan version 2 (T2), which substituted calf circumference for BMI, and with the long-form MNA-T2 as a referen...
Snack Selection Influences Nutrient Intake, Triglycerides, and Bowel Habits of Adult Women: A Pilot Study
Abstract: Because appropriate snacking can promote a healthy body weight and serve as an important contributor to a healthy diet for women, identification of suitable foods for incorporation between meals is essential. We investigated the influence of short-term (2 weeks) incorporation of 100-kcal servings of snacks of dried plums vs low-fat cookies twice daily on total energy and nutrient intake, biochemical parameters, and bowel habits in a randomized crossover design of two 2-week trials separated by a 2-week wash-out period in 26 women aged 25 to 54 years with a body mass index between 24 and 35. Incorporation of dried plums or low-fat cookies into the diet did not alter energy intake or weight; however, compared to cookies, dried plums promoted greater (P?0.05) intake of fiber, pota...
Fructose: Metabolic, Hedonic, and Societal Parallels with Ethanol
Abstract: Rates of fructose consumption continue to rise nationwide and have been linked to rising rates of obesity, type 2 diabetes, and metabolic syndrome. Because obesity has been equated with addiction, and because of their evolutionary commonalities, we chose to examine the metabolic, hedonic, and societal similarities between fructose and its fermentation byproduct ethanol. Elucidation of fructose metabolism in liver and fructose action in brain demonstrate three parallelisms with ethanol. First, hepatic fructose metabolism is similar to ethanol, as they both serve as substrates for de novo lipogenesis, and in the process both promote hepatic insulin resistance, dyslipidemia, and hepatic steatosis. Second, fructosylation of proteins with resultant superoxide formation can result in h...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Perceived Benefits, Barriers, and Strategies of Family Meals among Children with Type 1 Diabetes Mellitus and Their Parents: Focus-Group Findings
Abstract: Dietary management of type 1 diabetes mellitus has become much less restrictive and more flexible in recent years due to contemporary insulin regimens, which may afford families of children with type 1 diabetes mellitus greater ease in sharing family meals. Although these treatment advancements might facilitate family meals, overall demands of diabetes management can influence family's perceived or actual ability to do so. Youths with type 1 diabetes mellitus (ages 8 to 20 years) and parents participated in separate focus groups. Thirty-five youths with type 1 diabetes mellitus (mean age=15.1±3.6 years) and their parents participated in 21 focus groups (12 youth groups, nine parent groups). Although there was substantial variability in how often family meals occurred, both paren...
Are Ethanol and Fructose Similar?
In this issue, the review by Lustig, ?Fructose: Metabolic, Hedonic, and Societal Parallels with Ethanol? (), contains a juxtaposition of information on metabolic, inflammatory, and hormonal pathways from which the author suggests ?parallelism? between fructose and ethanol. The major premise of the review is that neither ethanol nor fructose provokes a satiety signal (insulin or leptin), so feedback on the consumption of these nutrients is lacking, leading to hedonic and societal consequences. The author further draws the parallel between alcoholic fatty liver disease (AFLD) and nonalcoholic fatty liver disease (NAFLD). He suggests the metabolic consequences of fructose and ethanol are also ?parallel? based on similarities in signaling pathways associated with the steatohepatiti...
Weighing in on Added Sugars and Health
In this issue of the Journal, Lustig contends that a reduction in fructose consumption is necessary to combat the obesity epidemic (). His review is one of many recently that is focused on the adverse health effects of increased intakes of sugars, especially added sugars and those coming from sugar-sweetened beverages. Although registered dietitians have for years focused on fat as the macronutrient most associated with chronic disease, it has become increasingly clear that the amount and quality of carbohydrates in the diet may be equally as important as fats to reduce diet-related chronic disease. (Source: Journal of the American Dietetic Association)
Registered Dietitians and Speech-Language Pathologists: An Important Partnership in Dysphagia Management
Swallowing difficulties, termed dysphagia, result in unsafe swallowing, and thus increase risk for inadequate food and fluid intake, aspiration pneumonia, and decreased cognitive and internal organ function. Swallowing is a complex process that relies on a series of well-timed and coordinated neuromuscular events. Initiation of swallowing is voluntary, but it is completed reflexively. Swallowing difficulties result from the delay, misdirection, or miscoordination of food and/or liquid as the material is transferred from the mouth to the stomach (). Eating often requires increased time and effort for the patient with dysphagia. Difficulties may result in a fear of eating or drinking, which in turn can limit food intake and lead to malnutrition, dehydration, and general decline. (Source: Jou...
A National Approach to Restaurant Menu Labeling: The Patient Protection and Affordable Health Care Act, Section 4205
As health care professionals and researchers continue their efforts to determine effective ways of addressing the continuing national struggle with overweight and obesity, legislators, too, have sought to do their part. (Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
ADA Value: Innovation
It is not the strongest of the species that survive, nor the most intelligent, but the one most responsive to change.?Charles Darwin Innovation?in short, a new way of doing something?can occur in small, incremental steps or in a radical or revolutionary way. To refer to someone as innovative generally has positive connotations that imply being ahead of the times, visionary, or forward-looking. Through ADA's core value of innovation, we constantly seek new ways to serve members, serve clients, and improve the way we deliver our work. (Source: Journal of the American Dietetic Association)
Sweet Obsession, Bitter Facts
Between 1970 and 2000, average daily consumption of sugar-sweetened beverages increased by 70%, from 7.8 oz/day to 13.2 oz/day, representing an extra 63 kcal/day that in 1 year is equivalent to a 6.7-lb weight gain from sugar alone (). A recent statement by the American Heart Association addressed the concerns related to this increasing intake and identified several potential problems ranging from diminished nutrient adequacy due to energy dense but nutrient poor sources, potential adverse impact on glucose-insulin response to these foods, and the contributions of the added sugar intake to the obesity epidemic that continues to rage across this country (). Children ages 14 to 18 years consume the highest amounts of added sugar, at approximately 34 teaspoons or the equivalent of 549 calorie...
This Month in the Journal of the American Dietetic Association
(Source: Journal of the American Dietetic Association)
Table of Contents
(Source: Journal of the American Dietetic Association)
Recipes for Health: Cooked Grains Salad With Tomato Vinaigrette
This robust summer salad can be made with a wide variety of grains. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections
Conclusion In conclusion, intake of the probiotic strains Lactobacillus plantarum HEAL 9 (DSM 15312) and Lactobacillus paracasei 8700:2 (DSM 13434) reduces the risk of acquiring common cold infections.
Content Type Journal ArticleDOI 10.1007/s00394-010-0127-6Authors
Anna Berggren, Probi AB, Ideon, Gamma 1, 223 70 Lund, SwedenIrini Lazou Ahrén, Probi AB, Ideon, Gamma 1, 223 70 Lund, SwedenNiklas Larsson, Probi AB, Ideon, Gamma 1, 223 70 Lund, SwedenGunilla Önning, Probi AB, Ideon, Gamma 1, 223 70 Lund, Sweden
Journal European Journal of NutritionOnline ISSN 1436-6215Print ISSN 1436-6207 (Source: European Journal of Nutrition)
2nd World Congress on Immunity Ingredients
28 October 2010
Radisson SAS Bay Point Resort, Malta
For more information, please visit www.immunity-site.com (Source: The Nutrition Society)
Author's reply: Low?dose eicosapentaenoic acid and/or docosahexaenoic acid and triglyceride lowering
(Source: Nutrition Reviews)
Low?dose eicosapentaenoic acid and/or docosahexaenoic acid and triglyceride lowering
(Source: Nutrition Reviews)
Nutrition Updates
(Source: Nutrition Reviews)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Health nutrition practice in Italy
The increasing need for nutrition professionals is driven by growing public interest in nutrition and the potential of nutrition to prevent and treat a variety of diet?related conditions. Health promotion units and health services face great challenges in trying to address current and future population health issues. This review describes the present state of health nutrition practice in Italy, exploring the nature, role, and utility of training for nutrition professionals to meet the increasing burden of nutrition?related diseases. Evidence suggests that the public health nutrition workforce and infrastructures lack the necessary capacity to respond to national population needs regarding food and nutrition at many levels. This situation is aggravated by the growing prevalence of nutri...
Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer
Isoflavones are phytoestrogens that have pleiotropic effects in a wide variety of cancer cell lines. Many of these biological effects involve key components of signal transduction pathways within cancer cells, including prostate cancer cells. Epidemiological studies have raised the hypothesis that isoflavones may play an important role in the prevention and modulation of prostate cancer growth. Since randomized phase III trials of isoflavones in prostate cancer prevention are currently lacking, the best evidence for this concept is presently provided by case control studies. However, in vitro data are much more convincing in regard to the activity of a number of isoflavones, and have led to the development of genistein and phenoxodiol in the clinic as potential treatments for cancer. In ad...
Omega?3 fatty acids in critical illness
The objective of this article is to review the data on supplementing omega?3 fatty acids during critical illness; enteral and parenteral supplemental nutrition are reviewed separately. The results of the research available to date are contradictory for both enteral and parenteral omega?3 fatty acid administration. Supplementation with omega?3 fatty acids may influence the acute inflammatory response in critically ill patients, but more research is needed before definitive recommendations about the routine use of omega?3 fatty acids in caring for critically ill patients can be made. (Source: Nutrition Reviews)
Use of ferrous fumarate to fortify foods for infants and young children
Ferrous fumarate is currently recommended for use in the fortification of foods for infants and young children. This recommendation is based on the compound's good sensory properties and on results from isotope studies in adults that reported similar iron absorption values for ferrous fumarate and ferrous sulphate (relative bioavailability [RBV] of ferrous fumarate, 100). However, later isotope studies conducted on both iron?replete and iron?deficient young children found that iron absorption from ferrous fumarate was only about 30% of that achieved from ferrous sulphate (RBV, 30). The reasons for the differences observed in adults compared with children are unclear but could be related to the following factors: lower iron status in children resulting in greater iron absorption via upr...
Impact of water intake on energy intake and weight status: a systematic review
The effects of consuming water with meals rather than drinking no beverage or various other beverages remain under?studied. This systematic review of studies reported in the English?language literature was performed to compare the effects of drinking water and various beverage alternatives on energy intake and/or weight status. Relevant clinical trials, epidemiologic studies, and intervention studies were identified and findings across the literature were summarized. From the clinical trials, average differences were calculated in total energy intake at test meals (?TEI) for each of several beverage categories in comparison with water. The available literature for these comparisons is sparse and somewhat inconclusive. However, one of the most consistent sets of findings was related to...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Eggs Being Produced by Recall Farms Safe, if Pasteurized, Experts Say
Title: Eggs Being Produced by Recall Farms Safe, if Pasteurized, Experts SayCategory: Health NewsCreated: 8/26/2010 12:10:00 PMLast Editorial Review: 8/27/2010 (Source: MedicineNet Digestion General)
Egg Recall: FDA Finds Salmonella on Suspect Farms
Title: Egg Recall: FDA Finds Salmonella on Suspect FarmsCategory: Health NewsCreated: 8/27/2010 9:58:00 AMLast Editorial Review: 8/27/2010 9:58:01 AM (Source: MedicineNet Digestion General)
Black Rice Is Cheap Way to Get Antioxidants
Title: Black Rice Is Cheap Way to Get AntioxidantsCategory: Health NewsCreated: 8/27/2010 10:06:00 AMLast Editorial Review: 8/27/2010 10:06:13 AM (Source: MedicineNet Digestion General)
BJN impact factor increases by 25 %.
Authors: Calder PC
PMID: 20735899 [PubMed - in process] (Source: The British Journal of Nutrition)
Advocacy and Public Policy Special Report: Disease-Related Malnutrition and Enteral Nutrition Therapy: A Significant Problem With a Cost-Effective Solution.
Authors:
PMID: 20802144 [PubMed - as supplied by publisher] (Source: Nutrition in Clinical Practice)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Carbohydrate mouth rinse: does it improve endurance exercise performance?
It is well known that carbohydrate (CHO) supplementation can improve performance in endurance exercises through several mechanisms such as maintenance of glycemia and sparing endogenous glycogen as well as the possibility of a central nervous-system action. Some studies have emerged in recent years in order to test the hypothesis of ergogenic action via central nervous system. Recent studies have demonstrated that CHO mouth rinse can lead to improved performance of cyclists, and this may be associated with the activation of brain areas linked to motivation and reward. These findings have already been replicated in other endurance modalities, such as running. This alternative seems to be an attractive nutritional tool to improve endurance exercise performance. (Source: Nutrition Journal)
[August 2010 Blogroll] Top Herbivore - Herbivoracious
Each post tells a short story with fancy-looking food but simple recipes. We love the creativity that comes through in his recipes, and the variety of ingredients and flavors that he draws from, which inspired and equipped us to try more meatless dishes. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Future events
(Source: Nutrition and Dietetics)
The Entrepreneurial Nutritionist
(Source: Nutrition and Dietetics)
Great Wealth Poor Health: Contemporary Issues in Eating and Living
(Source: Nutrition and Dietetics)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Obesity and female fecundity
(Source: Nutrition and Dietetics)
4th asia pacific nutrigenomics conference: 21?24 february 2010, auckland, new zealand
(Source: Nutrition and Dietetics)
Nutrition society of australia 33rd annual scientific meeting, 8?11 december 2009, newcastle, new south wales, australia
(Source: Nutrition and Dietetics)
28th National Dietitians Association of Australia: Lecture in Honour of Audrey Cahn
(Source: Nutrition and Dietetics)
Evaluation of the composition of omega?3 fatty acids in dietary oil supplements
Abstract (Source: Nutrition and Dietetics)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Development and validation of a three?item questionnaire for dietitians to screen for poor oral health in people living with human immunodeficiency virus and facilitate dental referral
Abstract (Source: Nutrition and Dietetics)
The Aboriginal Birth Cohort Study: When is a cohort study not a cohort design?
Abstract (Source: Nutrition and Dietetics)
Prediction of resting energy requirements in people taking weight?inducing antipsychotic medications
Abstract (Source: Nutrition and Dietetics)
Body composition in older orthopaedic rehabilitation inpatients: Are field methods valid?
Abstract (Source: Nutrition and Dietetics)
A novel approach to treating eating disorders in a day?hospital treatment program
Abstract (Source: Nutrition and Dietetics)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Bone density, calcium intake and vitamin D status in South Asian women living in Auckland, New Zealand
Abstract (Source: Nutrition and Dietetics)
Effect of a television programme on nutrition cognitions and intended behaviours
Abstract (Source: Nutrition and Dietetics)
Exposure to non?core foods and beverages in the first year of life: Results from a cohort study
Abstract (Source: Nutrition and Dietetics)
Appropriate introduction of solids: Another reason to promote breastfeeding
(Source: Nutrition and Dietetics)
Erratum
(Source: Nutrition and Dietetics)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Mentoring for professional development and the future of nutrition and dietetics
(Source: Nutrition and Dietetics)
From the editor
(Source: Nutrition and Dietetics)
Are The Eggs in Your Fridge Safe to Eat?
Title: Are The Eggs in Your Fridge Safe to Eat?Category: Health NewsCreated: 8/25/2010 12:10:00 PMLast Editorial Review: 8/26/2010 (Source: MedicineNet Digestion General)
Hemorrhoids
Title: HemorrhoidsCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 8/26/2010 (Source: MedicineNet Digestion General)
Recipes for Health: Bruschetta With Tomato Topping
In Greece this tomato mixture is served with rusks, thick slices of twice-baked bread. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sexual dimorphism in the lasting effects of moderate caloric restriction during gestation on energy homeostasis in rats is related with fetal programming of insulin and leptin resistance
Conclusion:
It is suggested that hyperinsulinemia may play a role in the etiology of hyperphagia in the offspring of caloric restricted animals during gestation, with different outcomes on body weight depending on the gender, which could be associated with different programming effects on later leptin resistance. (Source: Nutrition and Metabolism)
Predictive equations over-estimate the resting energy expenditure in amyotrophic lateral sclerosis patients who are dependent on invasive ventilation support
Conclusions:
The mREE values were significantly lower for every patient than all the predicted ones. Determination of daily nutrition with predictive equations may therefore lead in mis-estimation of energy requirements. Because ALS patients may live years with artificial ventilation their nutritional support should be based on individual measurements. However, further study is needed due to the small number of subjects. (Source: Nutrition and Metabolism)
Peoples Garden School Pilot Program
applications to enter into a cooperative agreement for the purposes of awarding grants to develop and run community gardens at eligible high-poverty schools and a variety of other activities. Geographic coverage: Nationwide -- USDA Food and Nutrition Service (Source: Food and hunger funding opportunities via the Rural Assistance Center)
Top Food and Nutrition Blogs You Should Check out
We've scouted numerous food and nutrition blogs on the web and found the best 8! Check them out now! Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Health Tip: Did You Eat Bad Food?
Title: Health Tip: Did You Eat Bad Food?Category: Health NewsCreated: 8/25/2010 10:10:00 AMLast Editorial Review: 8/25/2010 (Source: MedicineNet Digestion General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Diverticulitis (Diverticulosis)
Title: Diverticulitis (Diverticulosis)Category: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 8/25/2010 (Source: MedicineNet Digestion General)
Recipes for Health: Tomato Frittata With Fresh Marjoram or Thyme
This frittata makes for a perfect, substantial meal on a hot summer day. (Source: NYT)
When snacks become meals: How hunger and environmental cues bias food intake
Conclusions:
The present study demonstrated that environmental and situational cues associated with an eating occasion could influence overall food intake. People were more likely to eat foods when they were associated with meal cues. Importantly, the present study reveals that the effect of these cues is uniquely intertwined with cognition and motivation. First, people were more likely to eat ambiguous foods when they perceived them as a meal rather than a snack. Second, the effect of the environmental cues on intake was only observed among those who were hungry. (Source: International Journal of Behavioral Nutrition and Physical Activity)
Long-term increase of fat mass after a four week intervention with fast food based hyper-alimentation and limitation of physical activity
Conclusion:
One year after a short term intervention with increased fast food based hyper-alimentation there was an increase of fat mass but unchanged fat free mass. As the change of fat mass was larger than expected from epidemiological studies and as there was no increase of body weight in controls it raises the issue whether there is a long-term effect to increase fat mass of a short period of hyper-alimentation. (Source: Nutrition and Metabolism)
Thyroid volume in Swedish school children: a national, stratified, population-based survey
Authors: H Filipsson Nyström, M Andersson, G Berg, R Eggertsen, E Gramatkowski, M Hansson, L Hulthén, M Milakovic
& E Nyström (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Calcium and vitamin D intake and biochemical tests in short-stature children and adolescents
Authors: A L Bueno, M A Czepielewski
& F V Raimundo (Source: European Journal of Clinical Nutrition)
International Scientific Symposium: Biodiversity and sustainable diets united against hunger
3-5 November 2010
FAO Headquarters, Rome, Italy
For more information please visit www.fao.org/infoods/biodiversity. (Source: The Nutrition Society)
The role of body mass index, physical activity, and diet in colorectal cancer recurrence and survival: a review of the literature.
In conclusion, only a paucity of data is available on the effect of dietary and other lifestyle factors on colorectal cancer recurrence and survival. Thus far, no clear conclusions can be drawn. Future studies are warranted, particularly on postdiagnosis BMI and diet.
PMID: 20729339 [PubMed - in process] (Source: Am J Clin Nutr)
Calendar of events.
Authors:
PMID: 20729340 [PubMed - in process] (Source: Am J Clin Nutr)
Original Article: Household food insecurity is associated with depressive symptoms among low?income pregnant Latinas
(Source: Maternal and Child Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Original Article: Is baby?led weaning feasible? When do babies first reach out for and eat finger foods?
(Source: Maternal and Child Nutrition)
Health Tip: Help Prevent Bloating
Title: Health Tip: Help Prevent BloatingCategory: Health NewsCreated: 8/23/2010 10:10:00 AMLast Editorial Review: 8/24/2010 (Source: MedicineNet Digestion General)
Egg Recall: Trail Leads to Iowa Firm
Title: Egg Recall: Trail Leads to Iowa FirmCategory: Health NewsCreated: 8/24/2010 10:55:00 AMLast Editorial Review: 8/24/2010 10:55:55 AM (Source: MedicineNet Digestion General)
Rectal Cancer on the Rise in Young People
Title: Rectal Cancer on the Rise in Young PeopleCategory: Health NewsCreated: 8/24/2010 11:07:00 AMLast Editorial Review: 8/24/2010 11:07:36 AM (Source: MedicineNet Digestion General)
Personal Health: Frank Talk About Care at Life?s End
Under a new law in New York, physicians who treat patients with a terminal illness must offer information about prognosis and options for palliative care. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Really?: The Claim: Dark Cats Cause More Allergies Than Light Ones
Some scientists suspect that the darker a cat?s coat, the greater the likelihood of it inducing allergic reactions. (Source: NYT)
Recipe: Hot ham and cheese sandwiches with mushrooms
Hot ham and cheese sandwiches with mushrooms — one of many healthy recipes from Mayo Clinic. (Source: MayoClinic.com Recipe of the Day)
Lack of effects of tomato products on endothelial function in human subjects: results of a randomised, placebo-controlled cross-over study.
In conclusion, consumption of tomato products associated with a significant increase in plasma lycopene levels had no effects on endothelial function in healthy postmenopausal women.
PMID: 20735877 [PubMed - as supplied by publisher] (Source: The British Journal of Nutrition)
Supplementation with EPA or fish oil for 11 months lowers circulating lipids, but does not delay the onset of diabetes in UC Davis-type 2 diabetes mellitus rats.
In conclusion, EPA and fish oil supplementation lowers circulating lipid concentrations, but does not delay the onset of T2DM in UCD-T2DM rats.
PMID: 20735878 [PubMed - as supplied by publisher] (Source: The British Journal of Nutrition)
The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity
Conclusion:
These findings suggest that suppression of the inflammation pathways in macrophages represents a valid strategy for high-throughput screening of lead compounds with anti-diabetic and insulin sensitizing properties, and further support the etiological role of inflammation in the pathogenesis of obesity-related metabolic disorders. (Source: Nutrition and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Eggs: How Do You Know They're Safe? We've Compiled a Safe List
The massive egg recall announced last week rings an alarm bell to many people. The most shocking fact is, close to half a billion (with a B) were produced by just 2 farms in Iowa, Wright County and Hillandale Farm. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Recipes for Health: Tomatoes Pack a Nutritional Punch
Tomatoes, a staple of late summer, bring flavor and nutrients to a variety of light dishes. (Source: NYT)
[August 2010 Blogroll] Top Kid-Pleaser - Weelicious
Weelicious is a blog loaded with useful information if you have young children at home. Catherine McCord shows busy parents how to cook recipes that are kid-friendly, quick, and nutritious using few, but fresh, ingredients. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Nutrition Society Cuthbertson Medal 2010
The Nutrition Society is pleased to announce the winner of the Cuthbertson Medal for 2010, Dr Barbara Fielding from the Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK. Congratulations to Dr Fielding who will deliver the Cuthbertson Medal lecture at the Annual BAPEN conference on 3 November 2010. (Source: The Nutrition Society)
Nutrition Society Cuthbertson Medal 2010
The Nutrition Society is pleased to announce the winner of the Cuthbertson Medal for 2010, Dr Barbara Fielding from the Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK. Congratulations to Dr Fielding who will deliver the Cuthbertson Medal lecture at the Annual BAPEN conference on 3 November 2010. (Source: The Nutrition Society)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Parkinson's Disease
Title: Parkinson's DiseaseCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 8/23/2010 (Source: MedicineNet Digestion General)
Egg Recall: Frequently Asked Questions
Title: Egg Recall: Frequently Asked QuestionsCategory: Health NewsCreated: 8/23/2010 9:59:00 AMLast Editorial Review: 8/23/2010 9:59:19 AM (Source: MedicineNet Digestion General)
Reduction of common cold symptoms by encapsulated juice powder concentrate of fruits and vegetables: a randomised, double-blind, placebo-controlled trial.
Authors: Roll S, Nocon M, Willich SN
Dietary supplements have been suggested in the prevention of the common cold, but previous investigations have been inconsistent. The present study was designed to determine the preventive effect of a dietary supplement from fruits and vegetables on common cold symptoms. In a randomised, double-blind, placebo-controlled trial, healthcare professionals (mainly nursing staff aged 18-65 years) from a university hospital in Berlin, Germany, were randomised to four capsules of dietary supplement (Juice Plus+(R)) or matching placebo daily for 8 months, including a 2-month run-in period. The number of days with moderate or severe common cold symptoms within 6 months (primary outcome) was assessed by diary self-reports. We determined means and 95 % CI, and ...
The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals.
Authors: Pal S, Khossousi A, Binns C, Dhaliwal S, Ellis V
Optimum levels and types of dietary fibre that provide the greatest beneficial effects on metabolic syndrome risk factors in overweight and obese individuals have yet to be determined in clinical trials. The present parallel design study compared the effects of fibre intake from a healthy diet v. a fibre supplement (psyllium) or a healthy diet plus fibre supplement on fasting lipids, glucose, insulin and body composition. Overweight/obese adults were randomised to either control (with placebo), fibre supplement (FIB), healthy eating plus placebo (HLT) or healthy eating plus fibre supplement (HLT-FIB). There was a significant increase in fibre intake in HLT-FIB, HLT and FIB groups up to 59, 31 and 55 g, respectively, at 12 weeks ...
Gold kiwifruit consumed with an iron-fortified breakfast cereal meal improves iron status in women with low iron stores: a 16-week randomised controlled trial.
Authors: Beck K, Conlon CA, Kruger R, Coad J, Stonehouse W
Ascorbic acid, and more recently, the carotenoids lutein and zeaxanthin have been shown to enhance Fe absorption. However, it is not clear whether Fe status improves when foods high in ascorbic acid and carotenoids are consumed with Fe-fortified meals. The present study aimed to investigate whether consuming high v. low ascorbic acid-, lutein- and zeaxanthin-rich fruit (gold kiwifruit v. banana) with Fe-fortified breakfast cereal and milk improved Fe status in women with low Fe stores. Healthy women aged 18-44 years (n 89) with low Fe stores (serum ferritin </= 25 mug/l and Hb >/= 115 g/l) were randomly stratified to receive Fe-fortified breakfast cereal (16 mg Fe as ferrous sulfate), milk and either two gold kiwifruit or...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Genomic and metabolomic patterns segregate with responses to calcium and vitamin D supplementation.
Authors: Elnenaei MO, Chandra R, Mangion T, Moniz C
Inter-individual response differences to vitamin D and Ca supplementation may be under genetic control through vitamin D and oestrogen receptor genes, which may influence their absorption and/or metabolism. Metabolomic studies on blood and urine from subjects supplemented with Ca and vitamin D reveal different metabolic profiles that segregate with genotype. Genotyping was performed for oestrogen receptor 1 gene (ESR1) and vitamin D receptor gene (VDR) in fifty-six postmenopausal women. Thirty-six women were classified as low bone density as determined by a heel ultrasound scan and twenty women had normal bone density acting as 'controls'. Those with low bone density (LBD) were supplemented with oral Ca and vitamin D and were classifi...
Supplemental beta-carotene increases IgA-secreting cells in mammary gland and IgA transfer from milk to neonatal mice.
Authors: Nishiyama Y, Sugimoto M, Ikeda S, Kume S
Mortality of neonates continues to be a major problem in humans and animals. IgA provides protection against microbial antigens at mucosal surfaces. Although beta-carotene supplementation has been expected to enhance retinoic acid-mediated immune response in neonates, the exact mechanism by which beta-carotene enhances IgA production is still unclear. We investigated the effect of supplemental beta-carotene for maternal mice during pregnancy and lactation on IgA antibody-secreting cells (ASC) in mammary gland and guts and on IgA transfer from milk to neonatal mice. Pregnant mice were fed untreated or 50 mg/kg beta-carotene-supplemented diets from 6.5 d postcoitus (dpc) to 14 d postpartum (dpp). Supplemental beta-carotene increased the n...
Conference Diary
(Source: Nutrition Bulletin)
BNF Notices
(Source: Nutrition Bulletin)
BOOK REVIEW: Fat Matters: From Sociology to Science
(Source: Nutrition Bulletin)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
NEWS FROM EU RESEARCH: BaSeFood: sustainable exploitation of bioactive components from the Black Sea Area traditional foods
Summary (Source: Nutrition Bulletin)
NEWS FROM EU RESEARCH: Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan
Summary (Source: Nutrition Bulletin)
NEWS AND VIEWS: The possible impact of inflation on nutritionally vulnerable households in a developing country using South Africa as a case study
Summary (Source: Nutrition Bulletin)
NEWS AND VIEWS: Breakfast clubs: availability for British schoolchildren and the nutritional, social and academic benefits
Summary (Source: Nutrition Bulletin)
NEWS AND VIEWS: Government advice revised ? early life exposure to peanut no longer a risk factor for peanut allergy
(Source: Nutrition Bulletin)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
NEWS AND VIEWS: NDNS rolling programme ? what do the Year 1 results show?
Summary (Source: Nutrition Bulletin)
NEWS AND VIEWS: Ethnic foods in the UK
Summary (Source: Nutrition Bulletin)
NEWS AND VIEWS: Nine billion mouths to feed by 2050: the challenge of establishing a sustainable food supply
(Source: Nutrition Bulletin)
FACTS BEHIND THE HEADLINES: 5 A DAY and cancer prevention called into question
(Source: Nutrition Bulletin)
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