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Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" ...
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Regular Daily Intake of Black Tea Improves Oxidative Stress Biomarkers and Decreases Serum C-Reactive Protein Levels in Type 2 Diabetic Patients
Ann Nutr Metab 2010;57:40–49 (DOI:10.1159/000312666) (Source: Annals of Nutrition and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Bring Some Sourness To Your Dining Table
The best part of summer is the tasting the abundance of sweet and juicy fruit. But sometimes, sour can be good too! Sports nutritionist Lesli Bonci talks about the potential health benefits of tart or sour cherries. Click to listen now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Recipes for Health: Baked Limas With Tomatoes and Peppers
These baked beans are surprisingly sweet, though they contain no added sugars. (Source: NYT)
Personal Health: What Do You Lack? Probably Vitamin D
If recent findings hold up in future research, the consequences of vitamin D deficiency are likely to go far beyond excessive bone loss. (Source: NYT)
Protective effects of bovine colostrum acid proteins on bone loss of ovariectomized rats and the ingredients identification
Conclusions: BCAP (2-50 mg/day) could prevent osteoporosis caused by bone loss in OVX rats. (Source: Molecular Nutrition)
Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells
Conclusion: Our results indicate that treatment with a combination of TRAIL and naringenin may be a safe strategy for treatment of resistant NSCLC. (Source: Molecular Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo
Conclusion: These results suggest that the anti-inflammatory and pro-apoptotic activity of TF-2 may be exploited therapeutically in cancer and other diseases associated with inflammation. (Source: Molecular Nutrition)
Plasma folate levels are associated with the lipoprotein profile: a retrospective database analysis
Background:
Several studies demonstrated an association of homocysteine plasma levels and the plasma lipoprotein profile. This cross-sectional pilot study aimed at analyzing whether blood levels of the two important cofactors of homocysteine metabolism, folate and vitamin B12, coincide with the lipoprotein profile.
Methods:
In a retrospective single center approach, we analyzed the laboratory database (2003-2006) of the University Hospital Bonn, Germany, including 1743 individuals, in whom vitamin B12, folate and at least one lipoprotein parameter had been determined by linear multilogistic regression.
Results:
Higher folate serum levels were associated with lower serum levels of low density lipoprotein cholesterol (LDL-C; Beta=-0.164; p (Source: Nutrition Journal)
Association between alcohol consumption and carotid intima?media thickness in a healthy population: data of the STRATEGY study (Stress, Atherosclerosis and ECG Study)
Association between alcohol consumption and carotid intima–media thickness in a healthy population: data of the STRATEGY study (Stress, Atherosclerosis and ECG Study)
European Journal of Clinical Nutrition advance online publication, July 28, 2010. doi:10.1038/ejcn.2010.144
Authors: B-C Zyriax, K Lau, T Klähn, H Boeing, H Völzke
& E Windler (Source: European Journal of Clinical Nutrition)
Insulin-requiring diabetes in Ethiopia: associations with poverty, early undernutrition and anthropometric disproportion
Authors: S Fekadu, M Yigzaw, S Alemu, A Dessie, H Fieldhouse, T Girma, E R Trimble, D I W Phillips
& E H O Parry (Source: European Journal of Clinical Nutrition)
Increased plasma PYY levels following supplementation with the functional fiber PolyGlycopleX in healthy adults
Authors: R A Reimer, X Pelletier, I G Carabin, M Lyon, R Gahler, J A Parnell
& S Wood (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Effect of n-3 fatty acid enriched eggs and organic eggs on serum lutein in free-living lacto-ovo vegetarians
Authors: B L Burns-Whitmore, E H Haddad, J Sabaté, K Jaceldo-Siegl, J Tanzman
& S Rajaram (Source: European Journal of Clinical Nutrition)
Magnesium intake and type II diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study
Authors: A Nanri, T Mizoue, M Noda, Y Takahashi, K Kirii, M Inoue
& S Tsugane (Source: European Journal of Clinical Nutrition)
Coffee and endothelial function: a battle between caffeine and antioxidants?
Coffee and endothelial function: a battle between caffeine and antioxidants?
European Journal of Clinical Nutrition advance online publication, July 28, 2010. doi:10.1038/ejcn.2010.137
Authors: S Buscemi, J A Batsis, G Arcoleo
& S Verga (Source: European Journal of Clinical Nutrition)
Fat intake and asthma in Spanish schoolchildren
Authors: E Rodríguez-Rodríguez, J M Perea, A I Jiménez, P Rodríguez-Rodríguez, A M López-Sobaler
& R M Ortega (Source: European Journal of Clinical Nutrition)
Is the 1975 Reference Man still a suitable reference?
Is the 1975 Reference Man still a suitable reference?
European Journal of Clinical Nutrition advance online publication, July 28, 2010. doi:10.1038/ejcn.2010.125
Authors: W Later, A Bosy-Westphal, E Kossel, C-C Glüer, M Heller
& M J Müller (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Determinants of serum zinc concentrations in a population of French middle-age subjects (SU.VI.MAX cohort)
Authors: J Arnaud, M Touvier, P Galan, M Andriollo-Sanchez, D Ruffieux, A-M Roussel, S Hercberg
& A Favier (Source: European Journal of Clinical Nutrition)
Combination Drug Approved for High Blood Pressure
Title: Combination Drug Approved for High Blood PressureCategory: Health NewsCreated: 7/26/2010 4:10:00 PMLast Editorial Review: 7/27/2010 (Source: MedicineNet Digestion General)
Study Explores Links Between Obesity and Chronic Pain
Title: Study Explores Links Between Obesity and Chronic PainCategory: Health NewsCreated: 7/26/2010 12:10:00 PMLast Editorial Review: 7/27/2010 (Source: MedicineNet Digestion General)
Pleurisy (Pleuritis)
Title: Pleurisy (Pleuritis)Category: Diseases and ConditionsCreated: 2/20/2002 11:32:00 AMLast Editorial Review: 7/27/2010 (Source: MedicineNet Digestion General)
Vitamin D in the spotlight - time for urgent action?
Authors: Lanham-New S
PMID: 20646333 [PubMed - in process] (Source: The British Journal of Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Really?: The Claim: Exercise Can Worsen Chronic Heartburn
Can too much running induce acid reflux? (Source: NYT)
Recipes for Health: From the Bean Pot to the Table
With a bubbling pot of beans at hand, you can make soups, salads, even gratins. (Source: NYT)
Can Frozen Desserts be part of a Diabetes Meal Plan?
Are you worried that you can't have ice cream, popsicles or other frozen desserts as part of your diabetes meal plan? You are not alone - this can be a challenge for many people who have diabetes. It is possible for people with diabetes to incorporate frozen desserts into a balanced diabetes meal plan. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Avoid Mosquito Bites to Prevent Dengue Fever in Florida: Expert
Title: Avoid Mosquito Bites to Prevent Dengue Fever in Florida: ExpertCategory: Health NewsCreated: 7/23/2010 4:10:00 PMLast Editorial Review: 7/26/2010 (Source: MedicineNet Digestion General)
Irritable Bowel Syndrome in the Brain
Title: Irritable Bowel Syndrome in the BrainCategory: Health NewsCreated: 7/26/2010 9:34:00 AMLast Editorial Review: 7/26/2010 9:34:40 AM (Source: MedicineNet Digestion General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
New Pain Drug May Be Alternative to Oxycodone
Title: New Pain Drug May Be Alternative to OxycodoneCategory: Health NewsCreated: 7/26/2010 10:11:00 AMLast Editorial Review: 7/26/2010 10:11:03 AM (Source: MedicineNet Digestion General)
Where Can I Find Resources to Assist in the Determination of Pediatric Energy Needs that Account for Physical Activity of Child and Adolescent Athletes?
Registered dietitians and dietetic technicians, registered, are advocates for healthy eating and physical activity for children and adolescents early in their development. For children under the age of 6 years, active forms of play meet their need for physical activity. As children grow older, participation in organized sports can have physical and social benefits for children. The Federal Government's first-ever Physical Activity Guidelines for Americans () included the following key recommendations for children and adolescents aged 6 to 17 years: (Source: Journal of the American Dietetic Association)
August 2010 Classified Advertisements
(Source: Journal of the American Dietetic Association)
Erratum
In the article ?Development of a Diet Quality Index with Special Reference to Micronutrient Adequacy for Adolescent Girls Consuming a Lacto-Vegetarian Diet? by Chiplonkar and Tupe that appeared in the June 2010 Journal (pp 926-931), there is an error in Table 1 on page 928. The AMQI score for ?Food variety based on all subgroups and weekly variety in vegetables and fruits? should be 5, not 50, for the scoring criteria ?10, and 0 rather than a blank line for the scoring criteria (Source: Journal of the American Dietetic Association)
August 2010 People & Events
2010 ADA Food & Nutrition Conference & Expo November 6-9, 2010; Boston, MA (Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Position of the American Dietetic Association: Local Support for Nutrition Integrity in Schools
Abstract: It is the position of the American Dietetic Association (ADA) that schools and communities have a shared responsibility to provide students with access to high-quality, affordable, nutritious foods and beverages. School-based nutrition services, including the provision of meals through the National School Lunch Program and the School Breakfast Program, are an integral part of the total education program. Strong wellness policies promote environments that enhance nutrition integrity and help students to develop lifelong healthy behaviors. ADA actively supported the 2004 and proposed 2010 Child Nutrition reauthorization which determines school nutrition policy. ADA believes that the Dietary Guidelines for Americans should serve as the foundation for all food and nutrition assistanc...
Accepting Gifts: Let ADA's Professional Code of Ethics Be Your Guide
On the surface it might seem harmless to accept a gift from industry. However, it's important to consider the long-term consequences of short-term thinking. Principle 18 from the American Dietetic Association's (ADA's) Code of Ethics speaks to the responsibilities of the profession with regard to accepting gifts: ?The dietetics practitioner does not invite, accept, or offer gifts, monetary incentives, or other considerations that affect or reasonably give an appearance of affecting his/her professional judgment? (). In 2002, Coyle reported on studies surrounding ?industry influence on physician objectivity and behavior, particularly prescribing practices, formulary choices, and assessment of medical information,? in which research showed ?a strong correlation between receiving in...
Automated Camera-Phone Experience with the Frequency of Imaging Necessary to Capture Diet
Abstract: Camera-enabled cell phones provide an opportunity to strengthen dietary recall through automated imaging of foods eaten during a specified period. To explore the frequency of imaging needed to capture all foods eaten, we examined the number of images of individual foods consumed in a pilot study of automated imaging using camera phones set to an image-capture frequency of one snapshot every 10 seconds. Food images were tallied from 10 young adult subjects who wore the phone continuously during the work day and consented to share their images. Based on the number of images received for each eating experience, the pilot data suggest that automated capturing of images at a frequency of once every 10 seconds is adequate for recording foods consumed during regular meals, whereas a gre...
Food Label Use and Its Relation to Dietary Intake among US Adults
Abstract: Rates of diet-related chronic disease combined with the lack of current data on patterns of food label use by the US population warrant re-examination of the use and potential influence of this public health tool. The purpose of this study was to describe the prevalence of food label use and the association between food label use and nutrient intake in a nationally representative sample of US adults who participated in the 2005-2006 National Health and Nutrition Examination Survey. Data on food label use were collected during the interview portion of the survey, and nutrient intake was estimated using the average of two 24-hour dietary recalls. In this sample, 61.6% of participants reported using the Nutrition Facts panel, 51.6% looked at the list of ingredients, 47.2% looked at ...
The Beverage Intake Questionnaire: Determining Initial Validity and Reliability
Abstract: Consuming energy-containing beverages may lead to weight gain, yet research investigating this issue is limited. An easily administered beverage intake assessment tool could facilitate research on this topic. The purpose of this cross-sectional investigation was to determine the validity and reliability of a self-administered beverage intake questionnaire (BEVQ) that estimates mean daily intake of beverages consumed across 19 beverage categories. Participants (N=105; aged 39±2 years) underwent assessments of height, weight, body mass index, and dietary intake using 4-day food intake records from June 2008 to June 2009. The BEVQ was completed at two additional visits (BEVQ1, BEVQ2). Urine samples were collected to objectively determine total fluid intake and encourage accurate se...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Point-of-Purchase Nutrition Information Influences Food-Purchasing Behaviors of College Students: A Pilot Study
Abstract: The goal of point-of-purchase (POP) nutrition information is to help consumers make informed, healthful choices. Despite limited evaluation, these population-based approaches are being advocated to replace traditional, more expensive, individual behavior-change strategies. Few studies have examined the effect of POP information on buying patterns of college students, a group with high obesity rates and poor eating habits. This quasi-experimental pilot project sought to determine whether the ?Eat Smart? POP program affected food-purchasing habits of multiethnic college students shopping at an on-campus convenience store. Baseline sales data of foods in the cereal, soup, cracker, and bread categories were collected for 6 weeks during Fall 2008. After Winter break, a few food it...
Substituting Brown Rice for White Rice to Lower Diabetes Risk: A Focus-Group Study in Chinese Adults
This study assessed the awareness and acceptability of brown rice in Chinese adults, and examined the feasibility of introducing brown rice into the diet through a large, long-term randomized clinical trial to lower risk of type 2 diabetes. Thirty-two Chinese adults residing in Shanghai participated in this quantitative and qualitative study using questionnaires and focus-group discussions. Most participants (30 of 32) consumed white rice daily and only a few (n=8) had tried brown rice previously. Before tasting, most participants considered brown rice inferior to white rice in terms of taste and quality. However, after tasting brown rice and learning about its nutritional value, the majority indicated greater willingness to consume brown rice. Main barriers to acceptance were the percepti...
Place of Dairy Products in the Chinese-American Family Food System
Abstract: Chinese Americans have a high risk of osteoporosis and their calcium intake is substantially below the daily recommendation. However, little has been done to reduce the risk of this hard-to-reach population. This theory-based qualitative study explored how first-generation Chinese American couples with children view dairy products, how they use them in their family food system, and how these uses influence their dietary behavior or intake. Twenty couples, recruited from weekend Chinese schools at three locations in Pennsylvania, were interviewed. Taste, texture, and use of additives and growth hormones appeared to be more important influences on dairy choice than lactose intolerance. In these families, parental use of food rules and power to influence food patterns affected famil...
Pre- and Postnatal Health: Evidence of Increased Choline Needs
Abstract: Choline, a micronutrient found in food, serves as the starting material for several important metabolites that play key roles in fetal development, particularly the brain. Although human beings' requirement for choline is unknown, an Adequate Intake level of 425 mg/day was established for women with upward adjustments to 450 and 550 mg/day during pregnancy and lactation, respectively. The importance of choline in human development is supported by observations that a human fetus receives a large supply of choline during gestation; pregnancy causes depletion of hepatic choline pools in rats consuming a normal diet; human neonates are born with blood levels that are three times higher than maternal blood concentrations; and large amounts of choline are present in human milk. The dev...
Brief Telephone Intervention Increases Soy Intake in Peri- and Postmenopausal US Women: The Herbal Alternatives Trial (HALT)
Abstract: Objective: Effective dietary intervention strategies that can be widely disseminated and have the potential for sustainable dietary modifications are needed. The purpose of this study was to describe and evaluate the effectiveness of a telephone-based soy intervention.Design: A randomized controlled trial comparing self-reported intake and serum measures of soy during a 1-year dietary soy (Soy) to fruit and vegetable (Placebo) intervention conducted in two of five arms from the Herbal Alternatives Trial between May 2001 and September 2004.Subjects/setting: One hundred sixty-three peri- and postmenopausal women (mean age=52 years) consuming self-selected diets in the Pacific Northwest, United States.Intervention: Five telephone contacts with a registered dietitian during a 12-mont...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Shortening the Retention Interval of 24-Hour Dietary Recalls Increases Fourth-Grade Children's Accuracy for Reporting Energy and Macronutrient Intake at School Meals
Abstract: Background: Accurate information about children's intake is crucial for national nutrition policy and for research and clinical activities. To analyze accuracy for reporting energy and nutrients, most validation studies utilize the ?conventional approach,? which was not designed to capture errors of reported foods and amounts. The ?reporting-error-sensitive approach? captures errors of reported foods and amounts.Objective: To extend results to energy and macronutrients for a validation study concerning retention interval (elapsed time between to-be-reported meals and the interview) and accuracy for reporting school-meal intake, the conventional and reporting-error-sensitive approaches were compared.Design and participants/setting: Fourth-grade children (n=374) were observ...
Validation and Calibration of a Semiquantitative Food Frequency Questionnaire Designed for Adolescents
Conclusions: The tested FFQ is a suitable tool for ranking energy and nutrients intake in the studied group. Calibration factors are needed to estimate energy and nutrient intake means and should be used to correct raw data as well as association measurements based on FFQ data. (Source: Journal of the American Dietetic Association)
Dietary Behavior Assessment: Historical and Recent Innovations
Assessment of nutritional status involves the consideration of a complex array of factors across four major domains: dietary behavior, physical anthropometry, clinical history and examinations, and biochemical parameters (). Registered dietitians possess the unique training to guide and implement these assessments and to provide the careful interpretation of data needed to achieve the most accurate appraisal of nutritional risk in individuals and populations. Techniques of dietary behavior assessment and methodological validation are particularly important topics given their broad applications in nutrition research and clinical settings and relatively recent advances that may have profound practice implications. (Source: Journal of the American Dietetic Association)
The Importance of Being Choline
A discussion of the importance of choline first appeared in the 7th edition of the Recommended Dietary Allowances in 1968 (); however, it was not until 1998 that an adequate intake was established for choline (). At that time there was only a single study in normal men cited that provided evidence of a deleterious effect of a choline-deficient diet in humans (); data on women, infants, children, and older individuals were not available. Since that publication, additional evidence has accumulated about potential deleterious effects of choline deficiencies in men and premenopausal and postmenopausal women (). Scant data exist regarding choline needs of women during pregnancy and lactation or for infants and children, life stages when choline requirements might be expected to be increased. Th...
State Regulatory Specialist: A New Addition to Your Affiliate Public Policy Panel
The goal of the American Dietetic Association's (ADA's) affiliate public policy panels is to strengthen the grassroots structure of ADA to include a more comprehensive approach to shaping nutrition public policy. The panels develop a strong public policy agenda to increase grassroots influence in state initiatives impacting the registered dietitian (RD). The public policy panel, developed in 2006 by the Legislative and Public Policy Committee Grassroots Task Force, consists of several volunteer positions that work collaboratively with the affiliate president and leadership to help advance important federal and state legislative and policy issues. (Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Instant Mentoring: Sharing Wisdom and Getting Advice Online with E-Mentoring
The concept behind mentoring has existed since as early as ancient Greece, when Odysseus placed his friend Mentor in charge of his son Telemachus while he went off to fight in the Trojan War in the late 12th century BC. Obviously, we've come a long way since the days of Homer's Odyssey, but only recently have technological advances allowed for changes in the way mentoring is conducted, removing the necessity of meeting face-to-face whenever the mentee has a question or the mentor an idea to share. E-mail and the Internet have opened up new avenues for mentors and mentees to find and connect with each other?whether they work in the same office or on opposite sides of the globe. Today, nearly everything can be done through the Internet, from talking to friends across the world to ordering ...
Next on the Menu: Labeling Law Could Mean New Career Opportunities for RDs
The registered dietitians (RDs) of the American Dietetic Association (ADA) are always alert to new ways to improve the health of Americans and enhance the profile of the dietetics profession. So when President Obama signed the Health Care Reform bill into law, RDs?particularly those with an entrepreneurial spirit?saw an opportunity. (Source: Journal of the American Dietetic Association)
ADA Value: Customer Focus
One of the deep secrets of life is that all that is really worth doing is what we do for others.?Lewis Carroll One of the American Dietetic Association's four core values is Customer Focus, meaning we are determined to ?meet the needs and exceed the expectations of all customers.? According to the BNET Business Dictionary, customer focus is ?considered to be one of the keys to business success? (). Having a customer focus means having a belief in the spirit and tactics for achieving it. The whole organization must believe in and apply, in all our activities, a customer-focused approach. For ADA, our customers are members, but also the public and the collaborators who share our vision of health promotion through food and nutrition. (Source: Journal of the American Dietetic Associ...
A Garden of Variety
August is a time for savoring all the bounty from a carefully cultivated and well-stocked garden. Ranging from apricots to zucchini, the choices are ripe for picking. This month's Journal is likewise a diverse array of topics filled with ripened choices that can nourish your intellectual curiosity. (Source: Journal of the American Dietetic Association)
This Month in the Journal of the American Dietetic Association
(Source: Journal of the American Dietetic Association)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Table of Contents
(Source: Journal of the American Dietetic Association)
Calendar of events.
Authors:
PMID: 20647415 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
U.S. Stalls in Its Push to Limit Food Ads Aimed at Children
An effort to forge tougher advertising standards that favor healthful products has hit divisions among regulators. (Source: NYT)
The advent of home parenteral nutrition support.
Authors: Shils ME
I review here some key developments of personal and professional interest, with special reference to total parenteral nutrition (TPN), an area in which I have been involved from 1937 until recently. As a result of basic and biomedical science advances achieved in university and industrial laboratories in numerous countries, many essential nutrients were identified, synthesized, produced, and provided to patients in safe and effective forms both enterally and parenterally. This period also saw important developments in analytic instrumentation. I have had the privilege of seeing major advances in nutrition during my lifetime, and it is my belief and my hope for the future that with the advent of bowel transplants and tissue growth from cells, TPN will be a temporary me...
Compartmentalization of Mammalian folate-mediated one-carbon metabolism.
Authors: Tibbetts AS, Appling DR
The recognition that mitochondria participate in folate-mediated one-carbon metabolism grew out of pioneering work beginning in the 1950s from the laboratories of D.M. Greenberg, C.G. Mackenzie, and G. Kikuchi. These studies revealed mitochondria as the site of oxidation of one-carbon donors such as serine, glycine, sarcosine, and dimethylglycine. Subsequent work from these laboratories and others demonstrated the participation of folate coenzymes and folate-dependent enzymes in these mitochondrial processes. Biochemical and molecular genetic approaches in the 1980s and 1990s identified many of the enzymes involved and revealed an interdependence of cytoplasmic and mitochondrial one-carbon metabolism. These studies led to the development of a model of e...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Lipins: multifunctional lipid metabolism proteins.
Authors: Csaki LS, Reue K
The lipin proteins are evolutionarily conserved proteins with roles in lipid metabolism and disease. There are three lipin protein family members in mammals and one or two orthologs in plants, invertebrates, and single-celled eukaryotes. Studies in yeast and mouse led to the identification of two distinct molecular functions of lipin proteins. Lipin proteins have phosphatidate phosphatase activity and catalyze the formation of diacylglycerol in the glycerol-3-phosphate pathway, implicating them in the regulation of triglyceride and phospholipid biosynthesis. Mammalian lipin proteins also possess transcriptional coactivator activity and have been implicated in the regulation of metabolic gene expression. Here we review key findings in the field that demonstrate...
The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic Fatty liver disease associated with the metabolic syndrome.
Authors: Jornayvaz FO, Samuel VT, Shulman GI
The metabolic syndrome is a clustering of cardiovascular risk factors, including insulin resistance, abdominal obesity, dyslipidemia, and hypertension, and is associated with other comorbidities such as a proinflammatory state and nonalcoholic fatty liver disease (NAFLD). Its prevalence is high, especially among developed countries, and mainly reflects overnutrition and sedentary lifestyle. Moreover, the developing countries are not spared, as obesity and its related problems such as the metabolic syndrome are increasing quickly. We review the potential primary role of skeletal muscle insulin resistance in the pathophysiology of the metabolic syndrome, showing that in lean, young, insulin-resistant individuals, impaired muscle glucose transp...
The effect of nutrition on blood pressure.
Authors: Savica V, Bellinghieri G, Kopple JD
The incidence and severity of hypertension are affected by nutritional status and intake of many nutrients. Excessive energy intake and obesity are major causes of hypertension. Obesity is associated with increased activity of the renin-angiotensin-aldosterone and sympathetic nervous systems, possibly other mineralcorticoid activity, insulin resistance, salt-sensitive hypertension and excess salt intake, and reduced kidney function. High sodium chloride intake strongly predisposes to hypertension. Increased alcohol consumption may acutely elevate blood pressure. High intakes of potassium, polyunsaturated fatty acids, and protein, along with exercise and possibly vitamin D, may reduce blood pressure. Less-conclusive studies suggest that amino...
The endocannabinoid system and its relevance for nutrition.
Authors: Maccarrone M, Gasperi V, Catani MV, Diep TA, Dainese E, Hansen HS, Avigliano L
Endocannabinoids bind to cannabinoid, vanilloid, and peroxisome proliferator-activated receptors. The biological actions of these polyunsaturated lipids are controlled by key agents responsible for their synthesis, transport and degradation, which together form an endocannabinoid system (ECS). In the past few years, evidence has been accumulated for a role of the ECS in regulating food intake and energy balance, both centrally and peripherally. In addition, up-regulation of the ECS in the gastrointestinal tract has a potential impact on inflammatory bowel diseases. In this review, the main features of the ECS are summarized in order to put in better focus our current knowledge of the nutritional rel...
Recipes for Health: Spicy Grilled Eggplant Slices
In Italy, cooks often fry eggplant for this simple dish. Grilled eggplant works even better. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Effect of thiamine administration on metabolic profile, cytokines and inflammatory markers in drug-naïve patients with type 2 diabetes
Conclusions Thiamine administration for 1 month decreased glucose and leptin concentrations in drug-naïve patients with T2DM.
Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00394-010-0123-xAuthors
Manuel González-Ortiz, University of Guadalajara and Medical Research Unit in Clinical Epidemiology, Specialties Hospital, Medical Unit of High Specialty, West National Medical Center, Mexican Institute of Social Security Cardiovascular Research Unit, Physiology Department, Health Science University Center Montes Urales 1409 44340 Guadalajara, Colonia Independencia MexicoEsperanza Martínez-Abundis, University of Guadalajara and Medical Research Unit in Clinical Epidemiology, Specialties Hospital, Medical Unit of High Specialty, West National Medic...
Immunoregulatory effects of the flavonol quercetin in vitro and in vivo
Conclusion In vitro, quercetin reduced DC adhesion and oxLDL-induced DC differentiation. In vivo, quercetin reduced circulating plasmacytoid
DCs and systemic ADMA-levels. The immunoregulatory effects of quercetin may contribute to the anti-atherosclerotic potential
of flavonols.
Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-010-0125-8Authors
Thomas Nickel, Ludwig-Maximilians and University of Munich Medizinische Klinik und Poliklinik I, Campus Grosshadern 81377 Munich GermanyHenner Hanssen, Technische Universitaet Muenchen (TUM), Klinikum rechts der Isar (MRI) Department of Prevention and Sports Medicine Munich GermanyZeljka Sisic, Ludwig-Maximilians and University of Munich Medizinische Klinik und Poliklinik I, Campus Grosshadern 8137...
Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver
Conclusion Taken together, the results underline the potential of polyphenol-rich apple juice to increase the expression of ARE-dependent
antioxidant genes.
Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-010-0124-9Authors
Bülent Soyalan, University of Kaiserslautern Faculty of Chemistry, Food Chemistry & Toxicology 67663 Kaiserslautern GermanyJutta Minn, University of Kaiserslautern Faculty of Chemistry, Food Chemistry & Toxicology 67663 Kaiserslautern GermanyHans J. Schmitz, University of Kaiserslautern Faculty of Chemistry, Food Chemistry & Toxicology 67663 Kaiserslautern GermanyDieter Schrenk, University of Kaiserslautern Faculty of Chemistry, Food Chemistry & Toxicology 67663 Kaiserslautern GermanyFrank Will, Geisenheim Research Cen...
Travel Medicine: Healthcare When Traveling Abroad
Title: Travel Medicine: Healthcare When Traveling AbroadCategory: Doctor's ViewsCreated: 3/31/2006Last Editorial Review: 7/23/2010 (Source: MedicineNet Digestion General)
Association between adiposity and inflammatory markers in maternal and fetal blood in a group of Mexican pregnant women.
Authors: Vega-Sanchez R, Barajas-Vega HA, Rozada G, Espejel-Nuñez A, Beltran-Montoya J, Vadillo-Ortega F
In the present pilot study, we evaluated the effect of maternal adiposity on the plasma concentration of adipocytokines in pregnant women and their newborns. Twenty patients with term gestations without labour were initially selected by pregestational BMI and then classified into two study groups (n 10 each), according to their median value of adiposity (total body fat). Concentrations of TNF-alpha, IL-1beta, IL-6, leptin and adiponectin in plasma of maternal peripheral blood and fetal cord blood were measured and correlated to maternal adiposity. Maternal adiposity showed a significant negative correlation with fetal adiponectin (r - 0.587, P = 0.01) and IL-6 (r - 0.466, P = 0.0...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Plant-based food and feed protein structure changes induced by gene-transformation, heating and bio-ethanol processing: A synchrotron-based molecular structure and nutrition research program
Unlike traditional "wet" analytical methods which during processing for analysis often result in destruction or alteration of the intrinsic protein structures, advanced synchrotron radiation-based Fourier transform infrared microspectroscopy has been developed as a rapid and nondestructive and bioanalytical technique. This cutting-edge synchrotron-based bioanalytical technology, taking advantages of synchrotron light brightness (million times brighter than sun), is capable of exploring the molecular chemistry or structure of a biological tissue without destruction inherent structures at ultra-spatial resolutions. In this article, a novel approach is introduced to show the potential of the advanced synchrotron-based analytical technology, which can be used to study plant-based food or feed ...
Determinants of paraoxonase activity in healthy adults
Scope: Paraoxonase-1 (PON-1), associated with HDL, is regarded as anti-atherogenic, attributed to its ability to hydrolyze oxidized lipids. Here, the impact of PON and apolipoprotein E genotypes, age, alcohol and HDL-cholesterol (HDL-C) on PON activity is examined. Methods and results: In total, 104 healthy UK adults participated in the study, with basal (PONA) and stimulated (PONB) PON-1 activities and arylesterase activity determined in these individuals. In univariate and correlation analysis age, HDL-C, alcohol intake and both PON genotypes were significantly associated with PONA and PONB activities (p (Source: Molecular Nutrition)
Three Easy Ways to Cook Fish at Home
Fish is a super-healthy choice, no doubt about it. But somehow, it seems, when you're making home meal selections, fish just never seems to end up on the menu. Instead, you're more likely to choose beef,pork, or chicken. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Prenatal Vitamin Levels a Concern After Weight Loss Surgery
Title: Prenatal Vitamin Levels a Concern After Weight Loss SurgeryCategory: Health NewsCreated: 7/21/2010 4:10:00 PMLast Editorial Review: 7/22/2010 (Source: MedicineNet Digestion General)
Study Points to Molecular Origins of Celiac Disease
Title: Study Points to Molecular Origins of Celiac DiseaseCategory: Health NewsCreated: 7/21/2010 2:10:00 PMLast Editorial Review: 7/22/2010 (Source: MedicineNet Digestion General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Congestive Heart Failure
Title: Congestive Heart FailureCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 7/22/2010 (Source: MedicineNet Digestion General)
Recipes for Health: Smoky Eggplant and Yogurt Purée
Much like baba ganoush, this dish relies on yogurt instead of tahini for its unique flavor. (Source: NYT)
Pelvic Inflammatory Disease
Title: Pelvic Inflammatory DiseaseCategory: Diseases and ConditionsCreated: 9/15/2006Last Editorial Review: 7/21/2010 (Source: MedicineNet Digestion General)
Dengue Fever
Title: Dengue FeverCategory: Diseases and ConditionsCreated: 5/31/1998Last Editorial Review: 7/21/2010 (Source: MedicineNet Digestion General)
Pancreatitis
Title: PancreatitisCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 7/21/2010 (Source: MedicineNet Digestion General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Baseball Players Join First Lady to Fight Obesity
Thirty television and 30 radio spots, customized for each Major League Baseball team, will encourage children to become active. (Source: NYT)
Recipes for Health: Grilled Eggplant Purée With Pomegranate Syrup and Almonds
A unusual assortment of nutrients are found in this Turkish dish. (Source: NYT)
Serum concentrations of vitamin B12 and folate in British male omnivores, vegetarians and vegans: results from a cross-sectional analysis of the EPIC-Oxford cohort study
Authors: A M J Gilsing, F L Crowe, Z Lloyd-Wright, T A B Sanders, P N Appleby, N E Allen
& T J Key (Source: European Journal of Clinical Nutrition)
Response to the Letter entitled ?BMI, waist circumference and waist-to-hip ratio: diabetes mellitus types 2?
Response to the Letter entitled ‘BMI, waist circumference and waist-to-hip ratio: diabetes mellitus types 2’
European Journal of Clinical Nutrition advance online publication, July 21, 2010. doi:10.1038/ejcn.2010.129
Author: Q Qiao (Source: European Journal of Clinical Nutrition)
Effects of margarines and butter consumption on lipid profiles, inflammation markers and lipid transfer to HDL particles in free-living subjects with the metabolic syndrome
Authors: A C M Gagliardi, R C Maranhão, H P de Sousa, E J Schaefer
& R D Santos (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
BMI, waist circumference and waist-to-hip ratio: diabetes mellitus type 2
European Journal of Clinical Nutrition advance online publication, July 21, 2010. doi:10.1038/ejcn.2010.119
Author: V Wiwanitkit (Source: European Journal of Clinical Nutrition)
Dietary fat intake in relation to cognitive change in high-risk women with cardiovascular disease or vascular factors
Authors: M-N Vercambre, F Grodstein
& J H Kang (Source: European Journal of Clinical Nutrition)
Examination of facilitators and barriers to home-based supplemental feeding with ready-to-use food for underweight children in western Uganda
Poor complementary feeding practices and low-quality complementary foods are significant causes of growth faltering and child mortality throughout the developing world. Ready-to-use foods (RUF) are energy-dense, lipid-based products that do not require cooking or refrigeration that have been used to prevent and treat malnutrition among vulnerable children. The effectiveness of these products in improving child nutritional status depends on household use by caregivers. To identify the key facilitators and barriers that influence appropriate in-home RUF consumption by supplemental feeding program beneficiaries, we conducted individual interviews among caregivers (n = 80), RUF producers (n = 8) and program staff (n = 10) involved in the Byokulia Bisemeye mu Bantu supplemental feeding program ...
Coxsackie Virus
Title: Coxsackie VirusCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 7/20/2010 (Source: MedicineNet Digestion General)
Gastroenteritis (Stomach Flu)
Title: Gastroenteritis (Stomach Flu)Category: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 7/20/2010 (Source: MedicineNet Digestion General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
No associations between serum concentrations of 25-hydroxyvitamin D and parathyroid hormone and depression among US adults.
Authors: Zhao G, Ford ES, Li C, Balluz LS
Although there is evidence that vitamin D deficiency may play a role in depression, studies done on the associations have yielded mixed results. The present study aimed to examine the associations between serum concentrations of 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) and the presence of depression among US adults. A cross-sectional, population-based sample (including 3916 participants aged >/= 20 years) from the 2005-6 National Health and Nutrition Examination Survey was used. Participants' depressive symptoms were assessed using the Patient Health Questionnaire-9 diagnostic algorithm. The associations of 25(OH)D and PTH with depression were explored using multivariate logistic regression models. For all the participants...
Hypolipidaemic and antioxidative effects of oligonol, a low-molecular-weight polyphenol derived from lychee fruit, on renal damage in type 2 diabetic mice.
Authors: Noh JS, Kim HY, Park CH, Fujii H, Yokozawa T
Oligonol was orally administered at 10 or 20 mg/kg body weight per d for 8 weeks to db/db mice with type 2 diabetes, and its effects were compared with those of the vehicle in db/db and m/m (misty, non-diabetic) mice. Serum and renal biochemical factors, protein expressions related to lipid metabolism and inflammation, and advanced glycation endproducts were measured. There were significant reductions in the serum lipid concentration, reactive oxygen species (ROS) and lipid peroxidation, as well as improvements in renal function parameters. In addition, oligonol treatment significantly decreased ROS levels and lipid peroxidation in the kidney. In particular, the renal lipid contents such as TAG and total cholesterol were significant...
Nutrition Updates
(Source: Nutrition Reviews)
Optimizing clinical trial design for assessing the efficacy of functional foods
Randomized clinical trial data are capable of providing strong experimental evidence to establish causal relationships between functional food components and health and disease/disease risk. However, clinical studies must be well designed in order to optimize the quality of the data they provide. The purpose of this review is to identify design elements that maximize the quality of clinical trials examining the efficacy of functional foods. Both observational studies and experimental trials can provide useful data for identifying diet-disease relationships. Two experimental designs are conventionally used: parallel and crossover. Each of these designs possesses advantages and disadvantages. For certain functional ingredients, selection of an appropriate control arm is straightforward, whil...
Evidence-based criteria in the nutritional context
During the last decade, approaches to evidence-based medicine, with its heavy reliance on the randomized clinical trial (RCT), have been adapted to nutrition science and policy. However, there are distinct differences between the evidence that can be obtained for the testing of drugs using RCTs and those needed for the development of nutrient requirements or dietary guidelines. Although RCTs present one approach toward understanding the efficacy of nutrient interventions, the innate complexities of nutrient actions and interactions cannot always be adequately addressed through any single research design. Because of the limitations inherent in RCTs, particularly of nutrients, it is suggested that nutrient policy decisions will have to be made using the totality of the available evidence. Th...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Vitamin D inadequacy in pregnancy: biology, outcomes, and interventions
A high prevalence of maternal vitamin D inadequacy during pregnancy and at delivery has been demonstrated in various ethnic populations living at different latitudes. Because placental transfer of 25(OH)D is the major source of vitamin D to the developing human fetus, there is growing concern about adverse health impacts that hypovitaminosis D during pregnancy may have on the mother as well as the offspring in utero, in infancy, and later in life. While there is lack of consensus regarding the optimal circulating 25(OH)D concentration in pregnancy, it is evident that prior levels used to establish intake recommendations and vitamin D content of prenatal vitamin supplements were too conservative. This review summarizes vitamin D metabolism in the perinatal period, examines evidence regardin...
Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917
The beneficial effect of probiotic Escherichia coli strain Nissle 1917 (EcN) suggests the gut epithelium plays a basic role in immune interactions with bacteria. Contrary to other commensal strains of Escherichia coli, EcN profoundly modulates the gut barrier to elevate its resistance to microbial pathogens. The present review documents the properties of EcN that have led to the protection of gnotobiotic pigs against lethal enteric infections. This effect could be important in light of the growing number of acquired deficiencies that paralyze gut immunity in humans. (Source: Nutrition Reviews)
Validity of claims made in weight management research: a narrative review of dietetic articles
Conclusions:
Dietetic literature on weight management fails to meet the standards of evidence based medicine. Research in the field is characterised by speculative claims that fail to accurately represent the available data. There is a corresponding lack of debate on the ethical implications of continuing to promote ineffective treatment regimes and little research into alternative non-weight centred approaches. An alternative health at every size approach is recommended. (Source: Nutrition Journal)
Calcium from salmon and cod bone is well absorbed in young healthy men:a double-blinded randomised crossover design
Conclusion: We conclude that bones from Atlantic salmon and Atlantic cod are suitable as natural Ca sources in e.g. functional foods or as supplements. (Source: Nutrition and Metabolism)
Really?: The Claim: Artificial Sweeteners Can Raise Blood Sugar
Can a food labeled ?sugar free? affect sugar levels in your blood? (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Personal Health: Not Starting Means Never Having to Quit
Understanding the chemistry of nicotine addiction. (Source: NYT)
Personal Best: With This Rinse, Performance Improves
A carbohydrate solution that doesn?t even have to be swallowed gives athletes a boost, exercise scientists find. (Source: NYT)
Bring "Fancy Foods" into Your Home Kitchen
Think only TV chefs and top restaurants can get their hands on the gourmet ingredients needed to create fancy meals? Think again. I spotted some great new "fancy" foods to try at home at the 56th Summer Fancy Food Show and Food Fete in New York City. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Recipes for Health: Eggplant on the Grill
Nothing picks up the smoky flavor of a backyard grill quite like eggplant. (Source: NYT)
WCRF International Grant Application
World Cancer Research Fund (WCRF) International is now inviting applications for grants worldwide, except the Americas (North America including the USA and Canada, Central America, the Caribbean, and South America) to fund research into the effects of food, nutrition, physical activity and weight management on cancer. WCRF International may co-fund grants with other charities or trusts.
Deadline: 11 October 2010
See www.wcrf.org/apply for full details. (Source: The Nutrition Society)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Autistic Kids Often Fussier Eaters, but Nutrition OK
Title: Autistic Kids Often Fussier Eaters, but Nutrition OKCategory: Health NewsCreated: 7/19/2010 8:10:00 AMLast Editorial Review: 7/19/2010 (Source: MedicineNet Digestion General)
Non-Invasive Diagnosis of Inflammatory Bowel Disease Shows Promise
Title: Non-Invasive Diagnosis of Inflammatory Bowel Disease Shows PromiseCategory: Health NewsCreated: 7/16/2010 12:10:00 PMLast Editorial Review: 7/19/2010 (Source: MedicineNet Digestion General)
Strep Throat
Title: Strep ThroatCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 7/19/2010 (Source: MedicineNet Digestion General)
Huntington's Disease
Title: Huntington's DiseaseCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 7/19/2010 (Source: MedicineNet Digestion General)
Antioxidant responses to an acute ultra-endurance exercise: impact on DNA stability and indications for an increased need for nutritive antioxidants in the early recovery phase.
Authors: Neubauer O, Reichhold S, Nics L, Hoelzl C, Valentini J, Stadlmayr B, Knasmüller S, Wagner KH
Antioxidant requirements have neither been defined for endurance nor been defined for ultra-endurance athletes. To verify whether an acute bout of ultra-endurance exercise modifies the need for nutritive antioxidants, we aimed (1) to investigate the changes of endogenous and exogenous antioxidants in response to an Ironman triathlon; (2) to particularise the relevance of antioxidant responses to the indices of oxidatively damaged blood lipids, blood cell compounds and lymphocyte DNA and (3) to examine whether potential time-points of increased susceptibility to oxidative damage are associated with alterations in the antioxidant status. Blood that was collected from forty-two well-tr...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sugar intake and dental decay: results from a national survey of children in Scotland.
Authors: Masson LF, Blackburn A, Sheehy C, Craig LC, Macdiarmid JI, Holmes BA, McNeill G
The aim of this analysis was to investigate the strength of the association between sugar intake and treatment for dental decay in children in Scotland, and the impact of tooth brushing frequency on this association. The Survey of Sugar Intake among Children in Scotland was carried out in 2006 in those aged 3-17 years. Diet was assessed using the Scottish Collaborative Group FFQ, and interviews were carried out by trained fieldworkers who asked about dental health. A total of 1700 interviews were carried out, and 1512 FFQ were returned. Of the children, 56 % had received treatment for decay (fillings or teeth removed due to decay). Intake of non-milk extrinsic sugars (NMES), but not total sugar, in...
Reduction of salt: will iodine intake remain adequate in The Netherlands?
Authors: Verkaik-Kloosterman J, van 't Veer P, Ocké MC
Salt is the main vehicle for iodine fortification in The Netherlands. A reduction in salt intake may reduce the supply of iodine. Our aim was to quantify the effect of salt reduction on the habitual iodine intake of the Dutch population and the risk of inadequate iodine intake. We used data of the Dutch National Food Consumption Survey (1997-8) and an update of the food composition database to estimate habitual salt and iodine intake. To take into account uncertainty about the use of iodised salt (industrial and discretionary) and food supplements, a simulation model was used. Habitual iodine and salt intakes were simulated for scenarios of salt reduction and compared with no salt reduction. With 12, 25 and 50 % salt reduction i...
The choice of biomarkers determines the selenium status in young German vegans and vegetarians.
Authors: Hoeflich J, Hollenbach B, Behrends T, Hoeg A, Stosnach H, Schomburg L
Daily nutrition varies considerably among individuals. The number of vegetarians is increasing continuously due to ethical, environmental, religious or other reasons. There is growing concern over their nutritional status with respect to micronutrient deficiencies. Among the essential trace elements, Se is of prime importance as it is part of the active site in selenoproteins. European soil and plants are relatively poor sources of Se, while farm animals are generally supplemented with Se in order to improve their health and avoid deficiency syndromes. We therefore wondered whether German vegetarians display a measurable Se deficiency. To this end, we compared young vegetarians (n 54) and omnivores (n 53). W...
Author Index, Vol. 36, 1992
Ann Nutr Metab 1992;36:363-364 (DOI:10.1159/000177740) (Source: Annals of Nutrition and Metabolism)
Subject Index, Vol. 36, 1992
Ann Nutr Metab 1992;36:365-366 (DOI:10.1159/000177741) (Source: Annals of Nutrition and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Author Index, Vol. 37, 1993
Ann Nutr Metab 1993;37:335-336 (DOI:10.1159/000177785) (Source: Annals of Nutrition and Metabolism)
Author Index, Vol. 39,1995
Ann Nutr Metab 1995;39:380–381 (DOI:10.1159/000177890) (Source: Annals of Nutrition and Metabolism)
Subject Index, Vol. 39, 1995
Ann Nutr Metab 1995;39:382–383 (DOI:10.1159/000177891) (Source: Annals of Nutrition and Metabolism)
Declaration of Olympia on Nutrition and Fitness
Ann Nutr Metab 1996;40:312–314 (DOI:10.1159/000177930) (Source: Annals of Nutrition and Metabolism)
Author Index, Vol. 40, 1996
Ann Nutr Metab 1996;40:365–366 (DOI:10.1159/000177947) (Source: Annals of Nutrition and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Subject Index, Vol. 40, 1996
Ann Nutr Metab 1996;40:367–368 (DOI:10.1159/000177948) (Source: Annals of Nutrition and Metabolism)
Author Index, Vol. 41, 1997
Ann Nutr Metab 1997;41:383–384 (DOI:10.1159/000178012) (Source: Annals of Nutrition and Metabolism)
Subject Index, Vol. 41, 1997
Ann Nutr Metab 1997;41:385–386 (DOI:10.1159/000178013) (Source: Annals of Nutrition and Metabolism)
Recipe: Ham, pineapple and asparagus crepes
Ham, pineapple and asparagus crepes — one of many healthy recipes from Mayo Clinic. (Source: MayoClinic.com Recipe of the Day)
Big City: In New York, Getting Thin by Riding the Subway
Good news for New Yorkers: A study points to public transit?s role in staving off obesity. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Patient Money: Losing Weight the Smartphone Way, With a Nutritionist in Your Pocket
Many experts and consumers are excited about the new weight-loss apps available for iPhone, BlackBerry and other smartphones. (Source: NYT)
Four Recommended Apps for Losing Weight
Some weight-loss programs to consider. (Source: NYT)
2010 Healthy Sprouts Awards
These awards recognize and support youth gardening programs that provide education about the environment, nutrition, and hunger issues in the United States. Geographic coverage: Nationwide -- Gardener's Supply (Source: Food and hunger funding opportunities via the Rural Assistance Center)
Title Page / Table of Contents
Ann Nutr Metab 1991;35:I (DOI:10.1159/000177673) (Source: Annals of Nutrition and Metabolism)
Limitations of the Various Methods for Collecting Dietary Intake Data
Ann Nutr Metab 1991;35:81 (DOI:10.1159/000177682) (Source: Annals of Nutrition and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Methodological Problems in Micronutrient Intake Measurement
Ann Nutr Metab 1991;35:83 (DOI:10.1159/000177684) (Source: Annals of Nutrition and Metabolism)
Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment
Conclusion:
These data provide evidence that dietary mushrooms can inhibit cellular processes such as adhesion molecule expression and ultimate binding of monocytes to the endothelium under pro-inflammatory conditions, which are associated with CVD. As a result, these findings support the notion that dietary mushrooms can be protective against CVD. (Source: Nutrition Journal)
Recipes for Health: White Beans With Pesto
Try an unusual pesto or chermoula with cooked beans in this creamy salad. (Source: NYT)
Hospitalization trends in Spanish children and adolescents with eating disorders (1998-2007).
Authors: Lopez-de-Andres A, Carrasco-Garrido P, Hernández-Barrera V, Gil-de-Miguel A, Jiménez-Trujillo I, Jiménez-GarcÃa R
The study describes and analyzes the hospitalizations due to eating disorders (EDs) among children and adolescents during 1998-2007 in Spain. We conducted a retrospective study of national hospitalization data using the Minimum Basic Data Set. Hospitalization rates were calculated for EDs among children and adolescents aged 10-18 years. Length of hospital stay (median), psychiatric comorbidities, medical conditions and mortality rates were analyzed. There were a total of 10,569 EDs admissions during the period of study. The median length of hospital stay was greater in patients with anorexia than in those with bulimia (14 vs. 9 days). The most common ps...
Frozen Drinks Hall of Shame
Few people would eat ice cream every day, but many of us will buy one or more iced drinks to quench our thirst on a hot summer day. Frappuccinos (frozen coffee-type blended beverages), milkshakes and slurpees have permanent spots on the top frozen drinks list. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Subject Index
Ann Nutr Metab 1982;26:236-244 (DOI:10.1159/000176606) (Source: Annals of Nutrition and Metabolism)
Carbohydrate Sensitivity, Triglycerides and Uric Acid
Ann Nutr Metab 1984;28:409 (DOI:10.1159/000176854) (Source: Annals of Nutrition and Metabolism)
Distributions of the Dietary and Biological Parameters
Ann Nutr Metab 1986;30:80-86 (DOI:10.1159/000177235) (Source: Annals of Nutrition and Metabolism)
References - Bibliographie
Ann Nutr Metab 1986;30:87-94 (DOI:10.1159/000177236) (Source: Annals of Nutrition and Metabolism)
Author Index
Ann Nutr Metab 1989;33:235-236 (DOI:10.1159/000177539) (Source: Annals of Nutrition and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Preface
Ann Nutr Metab 1991;35:1 (DOI:10.1159/000177671) (Source: Annals of Nutrition and Metabolism)
Biological Markers of Dietary Intake, with Emphasis on Fatty Acids
Ann Nutr Metab 1991;35:82 (DOI:10.1159/000177683) (Source: Annals of Nutrition and Metabolism)
Author Index
Ann Nutr Metab 1991;35:119 (DOI:10.1159/000177691) (Source: Annals of Nutrition and Metabolism)
Subject Index
Ann Nutr Metab 1991;35:120 (DOI:10.1159/000177692) (Source: Annals of Nutrition and Metabolism)
Chemical and electrophoretic properties of Holstein cow milk as affected by somatic cell count
Chemical and electrophoretic properties of raw milk samples with different somatic cell counts (SCCs)(800 000 cells/mL) were determined. Milk was analysed for fat, lactose, total nitrogen (TN), non-casein nitrogen (NCN), ratio of casein nitrogen to total nitrogen (CN/TN), pH, titratable acidity (TA), solid-non-fat (SNF), total solid (TS), the amount of [alpha]s-casein and [beta]-casein. Milk SCC had no significant effect (P [ge] 0.05) on fat and TN. An increase in the SCC resulted in an increase in pH and NCN content, and a significant decrease in lactose, TA, SNF, CN/TN, [alpha]s-casein and [beta]-casein. Milk quality of Holstein dairy cattle deteriorate due to higher proteolytic activity associated with high SCC. (Source: International Journal of Dairy Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Hungry Girl Offers a Real Take on Diet Foods
Lisa Lillien ? also known as Hungry Girl ? sends out an e-mail newsletter to almost a million subscribers, offering a sweet moment of pleasure in the daily slog of dieting. (Source: NYT)
Postprandial energy expenditure in whole-food and processed-food meals: implications for daily energy expenditure.
CONCLUSION: Ingestion of the particular PF meal tested in this study decreases postprandial energy expenditure by nearly 50% compared with the isoenergetic WF meal. This reduction in daily energy expenditure has potential implications for diets comprised heavily of PFs and their associations with obesity.
PMID: 20613890 [PubMed - in process] (Source: Food and Nutrition Research)
Dengue Infection Re-Emerges in Florida: CDC
Title: Dengue Infection Re-Emerges in Florida: CDCCategory: Health NewsCreated: 7/14/2010 8:10:00 AMLast Editorial Review: 7/14/2010 (Source: MedicineNet Digestion General)
Health Tip: What May Trigger a Hernia
Title: Health Tip: What May Trigger a HerniaCategory: Health NewsCreated: 7/14/2010 8:10:00 AMLast Editorial Review: 7/14/2010 (Source: MedicineNet Digestion General)
Association Found Between Alzheimer's and Anemia
Title: Association Found Between Alzheimer's and AnemiaCategory: Health NewsCreated: 7/13/2010 8:10:00 PMLast Editorial Review: 7/14/2010 (Source: MedicineNet Digestion General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for<b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Determination of Some Chemical Parameters and Antimicrobial Activity of Traditional Food: Mesir Paste
Journal of Medicinal Food , Vol. 0, No. 0. (Source: Journal of Medicinal Food)
Relation of isoflavones and fiber intake in childhood to the timing of puberty.
CONCLUSIONS: Girls, but not boys, with higher prepubertal isoflavone intakes appear to enter puberty at a later age. Fiber intake in this sample of healthy white girls and boys was not relevant for puberty timing.
PMID: 20631200 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Gestational weight gain in obese mothers and associations with fetal growth.
CONCLUSION: Our study suggests a GWG below the IOM guidelines may be associated with more favorable BW for all obese women, and GWG may need to be further defined by obesity severity.
PMID: 20631201 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer.
CONCLUSIONS: The standardized phase angle is an independent predictor for impaired nutritional and functional status and survival. The fifth phase angle reference percentile is a simple and prognostically relevant cutoff for detection of patients with cancer at risk for these factors.
PMID: 20631202 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
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Researching Fibromyalgia By Groshan Fabiola Scientist are working very hard to better understand what causes fibromyalgia, or what problems accompany this disease. This way they are improving the odes of a correct diagnose, better treatment and also prevention of the illness. Universities and special medical institutions, like NIAMS, are covering a wide spectrum when it comes to research. They are doing detailed laboratory work in studying new medications for the drugs and the good and bad effects that they have on the patient. Special treatments are also being researched so that people with this disorder don't have to suffer as much from the pain. A particular part of their studies investigates the use of special interventions to encourage certain behaviors that help in reducing the level of pain; through this they are also trying to eliminate behaviors that actually worsen or help in perpetuating the pain. A significant part of the studies done by researchers is actually done to better understand the pain. Some scientist suggest that the problem with patients is that they actually have difficulty in proper processing the amount of pain that they feel. In other words it seams that people with this illness have a hypersensitivity to stimuli that normally are not that
Impact of Childhood Obesity Goes Beyond HealthThe health effects of being overweight or obese are well documented. Extra pounds add extra risk for diabetes, heart disease and certain cancers, even among children. But new research also documents significant social and economic consequences of being overweight since high school. (Source: RWJF News Digest - Childhood Obesity)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Diabetes care: Implanted glucose sensor works for more than a year in animal studiesBioengineers have developed an implantable glucose sensor and wireless telemetry system that continuously monitors tissue glucose and transmits the information to an external receiver. A new article describes the use of this glucose-sensing device as an implant in animals for over one year. After human clinical trials and FDA approval, the device may be useful to people with diabetes as an alternative to finger sticking and short-term, needle-like glucose sensors that have to be replaced every three to seven days. (Source: ScienceDaily Headlines)Women with gestational diabetes have increased risk of recurrence in subsequent pregnancies, study findsThere is an increased risk of recurring gestational diabetes in pregnant women who developed gestational diabetes during their first and second pregnancies, according to new study. (Source: ScienceDaily Headlines)Poorly controlled diabetes linked to reduced lung functionPoor glycemic control is associated with reduced lung function in patients with Type 2 diabetes, study results suggest. (Source: MedWire News - Respiratory)Pharmaceutical drug contamination of waterways threatens life on our planetThis study was the first national-scale evaluation of pharmaceutical drug contamination in streams, and roughly 80 percent of the streams tested were found to be contaminated as well.In 2008, an AP investigation found that at least 46 million Americans are drinking water contaminated with trace amounts of pharmaceuticals. Even though every city tested has its water treated and "purified" prior to being delivered to the public, trace amounts of pharmaceutical drugs are making their way through to the tap. (Since not all major metropolitan areas were tested, the number of people affected is likely far higher than what was reported by AP.)In spite of all this, water quality reports don't disclose the levels of pharmaceuticals found in tap water. Since the EPA and FDA have failed to establish ...Vitamin D is essential for activating immune system function(NaturalNews) Researchers have discovered that vitamin D plays a crucial role in activating the immune system's ability to recognize and fight pathogens.While scientists have long known that vitamin D plays a critical role in bone health, recent research has begun to suggest that it also serves to regulate the immune system, helping prevent infection, cancer and autoimmune disorders. Until now, the mechanism by which the vitamin acts on the immune system has been unknown.In a study published in the journal Nature Immunology, researchers from the University of Copenhagen found that when a variety of white blood cells known as a T-cell comes across a pathogen in the bloodstream, it extends a receptor in search of vitamin D. If it encounters the vitamin, the T cell becomes "activated." If the...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>CVD risk rises in line with HbA1c in Type 2 diabetesStudy findings from the Swedish National Diabetes Register show that the risk for cardiovascular disease in people with Type 2 diabetes increases progressively with increasing glycated hemoglobin levels. (Source: MedWire News - Diabetes)Animal models and biomarkers of neuropathy in diabetic rodentsAS Shaikh, RS SomaniIndian Journal of Pharmacology 2010 42(3):129-134Diabetic neuropathy (DN) is a multifactor complication of diabetes. It is a late finding in type 1 diabetes, but can be an early finding in type 2 diabetes. The cause of DN is still unclear and, like other complications of diabetes, it may be the result of various pathological conditions. Animal models and biomarkers of DN have been extensively used in neuropathic research. The most useful model of DN should exhibit the key feature present in human pathology. Diabetic rodents show behavioral, functional, structural and molecular biomarkers and they are widely used as models to investigate the etiology of DN as well as to screen the efficacy of the potential therapeutic interventions. We have reviewed the different animal ...Effect of saturated fatty acid-rich dietary vegetable oils on lipid profile, antioxidant enzymes and glucose tolerance in diabetic ratsConclusion : The type of FA in the dietary oil determines its deleterious or beneficial effects. Lauric acid present in CO may protect against diabetes-induced dyslipidemia. (Source: Indian Journal of Pharmacology)Irbesartan in experimental diabetic nephropathyRajiv Mahajan, Kapil Gupta, Navyug Raj SinghIndian Journal of Pharmacology 2010 42(3):197-197 (Source: Indian Journal of Pharmacology)Treatment of post-burn neuropathic pain: Evaluation of pregablinWe report our experience with pregabalin for the treatment of post-burn neuropathic pain. A retrospective review of patients treated with pregabalin in a burn outpatient clinic was undertaken. A numerical pain scale was administered to each patient prior to and after treatment to determine efficacy. Side effects and reasons for discontinuation were noted. Out of 24 patients 4 patients were lost to followup, 5 patients discontinued taking pregabalin and 2 patients had incomplete data for evaluation. Of the remaining 13 patients, 69% (11) had a reduction in pain score after treatment. In addition, 2 of the patients who discontinued use had a pain score which decreased to 0. Pregabalin is a well-tolerated, effective means of treating post-burn neuropathic pain. Time to achieve effective dosin...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Removal of Contrast Media From the Coronary Sinus Attenuates Renal Injury After Coronary Angiography and InterventionAcute renal injury after exposure to radiographic contrast media, contrast-induced nephropathy (CIN), accounts for a substantial proportion of all cases of acute renal failure (). The incremental presence of predisposing factors including pre-existing chronic renal impairment, contrast load, diabetes, and advancing age contribute significantly to the risk of CIN, which may exceed 30% in the highest-risk patients (). Due to common risk factors, patients undergoing coronary angiography or coronary intervention represent a particularly high-risk group. The development of CIN is a major source of clinical concern for several reasons. First, contrast-induced renal injury may in some cases contribute to a permanent worsening of renal function, in some cases requiring temporary or even permanent ...Genetic markers in diabetes mellitus: the need and promise for specific drug therapies in defined subtypes of diabetes patientsTherapy , July 2010, Vol. 7, No. 4, Pages 309-312. (Source: Future Medicine: Therapy)Regular Daily Intake of Black Tea Improves Oxidative Stress Biomarkers and Decreases Serum C-Reactive Protein Levels in Type 2 Diabetic PatientsAnn Nutr Metab 2010;57:40–49 (DOI:10.1159/000312666) (Source: Annals of Nutrition and Metabolism)Selective autophagy regulates various cellular functionsAutophagy is a self-eating system conserved among eukaryotes, in which cellular components including organelles are entrapped into a double membrane structure called the autophagosome and then degraded by lysosomal hydrolases. In addition to its role in supplying amino acids in response to nutrient starvation, autophagy is involved in quality control to maintain cell health. Thus, inactivation of autophagy causes the formation of cytoplasmic protein inclusions, which comprise misfolded proteins and the accumulation of many degenerated organelles, resulting in liver injury, diabetes, myopathy and neurodegeneration. Furthermore, although autophagy has been considered nonselective, increasing evidence points to the selectivity of autophagy in sorting vacuolar enzymes and removal of aggregate-...Disease management changes course to improve its outcomesWhen disease management began, it just entailed a series of programs with a singular focus. Whether
you had asthma, coronary artery disease, heart failure, diabetes or COPD, disease management programs managed only
one chronic illness at a time. (Source: Managed Healthcare Executive Magazine Online)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Antioxidant enzymatic defense in salivary glands of streptozotocin-induced diabetic rats: a temporal studyIn this study, we analyzed the antioxidant enzymatic defense and the lipid peroxidation of rat salivary glands in six different periods of diabetic condition. Ninety-six rats were divided into 12 groups: C7/14/21/28/45/60 (non-diabetic animals) and D7/14/21/28/45/60 (diabetic animals). Diabetes was induced by streptozotocin and the rats were euthanized after 7, 14, 21, 28, 45, or 60 days. Their parotid (PA) and submandibular (SM) glands were removed soon after the sacrifice and the total protein and malondialdehyde (MDA) concentrations, as well as, the superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) activities were determined. Twenty-one days after the diabetes induction, the SM glands showed an increase in SOD, CAT, and GPx activities, as well as, MDA concentr...Sensor implant monitors blood sugarAn implantable sensor that continuously monitors glucose levels has worked for more than a year in a pig, raising hopes for use in human diabetics, researchers report. (Source: CBC | Health)Why Fad Diets Work Well for Some, But Not OthersJuly 28, 2010 (EurekAlert) - Ever notice some people seem to eat anything they want and never gain a pound, while others seem to gain weight just by looking at fattening foods? You may be seeing things correctly after all. According to research published in the July 2010 issue of Genetics, this may have a biological cause.
read more (Source: Diabetes News from dLife.com)Why Fad Diets Work Well for Some, But Not OthersJuly 28, 2010 (EurekAlert) - Ever notice some people seem to eat anything they want and never gain a pound, while others seem to gain weight just by looking at fattening foods? You may be seeing things correctly after all. According to research published in the July 2010 issue of Genetics, this may have a biological cause.
read more (Source: Diabetes News from dLife.com)Diabetic KK-Ay mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophenIn this study, therefore, we investigated acetaminophen-induced liver injury in KK-Ay mice, an animal model of metabolic syndrome. Twelve-week-old male KK-Ay and C57Bl/6 mice were injected intraperitoneally with 300 or 600 mg/kg acetaminophen, and euthanized 6 h later. Liver histology was assessed, and hepatic expression of 4-hydroxy-2-nonenal was detected by immunohistochemistry. Levels of reduced glutathione were determined spectrophotometrically. Phosphorylation of c-Jun NH2-terminal kinase (JNK) was analyzed by Western blotting. Hepatocytes were isolated from both strains by collagenase perfusion, and cell death and oxidative stress were measured fluorometrically by use of propidium iodide and 5-(and-6)-chloromethyl-2'7'-dichloro-dihydrofluorescein diacetate acetyl ester, respectively....<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Pancreatic acinar-specific overexpression of Reg2 gene offered no protection against either experimental diabetes or pancreatitis in miceReg proteins are normally expressed in pancreatic acinar cells, and the level of several of these proteins was significantly induced upon damage to the endocrine or exocrine pancreas. It has been established that Reg1 and pancreatic islet neogenesis-associated protein [INGAP, Reg3] promote the growth or regeneration of the endocrine islet cells. Recent reports suggest that Reg2 is an autoantigen normally expressed in islet β-cells. Reg2 overexpression in vitro offered protection to insulinoma cells. Overexpressed Reg3 increased cyclin D1 and CDK4 levels and the rate of proliferation in insulinoma cells. Acinar-specific overexpression of INGAP increased β-cell mass and protected the animals from streptozotocin-induced diabetes. Moreover, Reg2 gene expression was induced during pan...In Young Girls, Obesity Linked to Early Puberty, Analysis RevealsUnanswered questions remain, including psychological impact, researcher says (Source: The Doctors Lounge - Health News)In Young Girls, Obesity Linked to Early Puberty, Analysis RevealsUnanswered questions remain, including psychological impact, researcher says (Source: The Doctors Lounge - Health News)Wireless sensor watches blood sugar for diabeticsWASHINGTON (Reuters) - Researchers have developed an implantable sensor that measures blood sugar continuously and transmits the information without wires -- a milestone, they said, in diabetes treatment. (Source: Reuters: Health)A Multiplex Immunoassay for Human Adipokine Profiling [Articles]CONCLUSIONS:
Our findings underscore the relevance of the novel adipokines cathepsin S and chemerin, but foremost the potential of this novel method for both comprehensive adipokine profiling in large patient cohorts and for biological discovery. (Source: Clinical Chemistry)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Lipoprotein(a) and Risk of Type 2 Diabetes [Lipids, Lipoproteins, and Cardiovascular Risk Factors]CONCLUSIONS:
Our results indicated that Lp(a) was associated inversely with risk of type 2 diabetes independently of risk factors, in contrast to prior findings of positive associations of Lp(a) with cardiovascular risk. (Source: Clinical Chemistry)Implantable Sensor Measures Blood Sugar LevelsWireless device transmitted accurate readings in pigs for more than a year, study shows (Source: The Doctors Lounge - Health News)Free Diabetes Education and Support Groups in FloridaOngoing diabetes education and support groups are offered for free in numerous locations. These groups are invaluable for anyone who is living with either type 1 or type 2 diabetes. These groups are particularly informative for anyone who has just recently been diagnosed and needs guidance on coping methods. Caregivers are encouraged to attend meetings with their loved ones. Guest speakers come and lecture on various topics.
Group 1: August 4th at 10 AM
Coral Springs Medical Center
3100 Coral Hills Dr., Conference Room A
read more (Source: Diabetes News from dLife.com)Free Diabetes Education and Support Groups in FloridaOngoing diabetes education and support groups are offered for free in numerous locations. These groups are invaluable for anyone who is living with either type 1 or type 2 diabetes. These groups are particularly informative for anyone who has just recently been diagnosed and needs guidance on coping methods. Caregivers are encouraged to attend meetings with their loved ones. Guest speakers come and lecture on various topics.
Group 1: August 4th at 10 AM
Coral Springs Medical Center
3100 Coral Hills Dr., Conference Room A
read more (Source: Diabetes News from dLife.com)One Molecule, Many More Insulin-Producing Cells to Treat Diabetes, Says Pitt TeamJuly 28, 2010 (EurekAlert) - With a single stimulatory molecule, human insulin-producing beta cell replication can be sustained for at least four weeks in a mouse model of diabetes, according to researchers at the University of Pittsburgh School of Medicine in Diabetes, a journal of the American Diabetes Association.
read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>One Molecule, Many More Insulin-Producing Cells to Treat Diabetes, Says Pitt TeamJuly 28, 2010 (EurekAlert) - With a single stimulatory molecule, human insulin-producing beta cell replication can be sustained for at least four weeks in a mouse model of diabetes, according to researchers at the University of Pittsburgh School of Medicine in Diabetes, a journal of the American Diabetes Association.
read more (Source: Diabetes News from dLife.com)South Africa: Gauteng Citizens Urged to Vaccinate Against H1N1Gauteng Department of Health and Social development is urging pregnant women, patients with chronic lung and heart diseases, diabetic, school going learners under the age of 20 as well as senior citizens over 65 years to immunize against H1N1 virus by Friday, 31 July 2010. (Source: AllAfrica News: Health and Medicine)New weight advice for pregnancyMany newspapers have reported on new official guidelines for how women can manage their weight before, during and after pregnancy. The advice comes from the National Institute for Health and Clinical Excellence (NICE).
The importance of the guidelines are borne out by figures suggesting that more mothers than ever are overweight. The Guardian suggests that, ?15-20% of women getting pregnant are overweight or obese?. The Daily Mail puts the number higher, saying that ?almost half of expectant mothers are overweight or obese?. It goes on to spell out the dangers of being obese or overweight during pregnancy, which include ?fatal health conditions such as blood clots, pre-eclampsia, miscarriages and stillbirths?.
The newspapers also dispel the myth that women should eat for two du...PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium PathwaysPeroxisome proliferator-activated receptors (PPAR α, β/δ and γ) play a key role in metabolic regulatory processes and gene regulation of cellular metabolism, particularly in the cardiovascular system. Moreover, PPARs have various extra metabolic roles, in circadian rhythms, inflammation and oxidative stress. In this review, we focus mainly on the effects of PPARs on some thermodynamic processes, which can behave either near equilibrium, or far-from-equilibrium. New functions of PPARs are reported in the arrhythmogenic right ventricular cardiomyopathy, a human genetic heart disease. It is now possible to link the genetic desmosomal abnormalitiy to the presence of fat in the right ventricle, partly due to an overexpression of PPARγ. Moreover, PPARs are...The Role of Peroxisome Proliferator-Activated Receptor β/δ on the Inflammatory Basis of Metabolic DiseaseThe pathophysiology underlying several metabolic diseases, such as obesity, type 2 diabetes mellitus, and atherosclerosis, involves a state of chronic low-level inflammation. Evidence is now emerging that the nuclear receptor Peroxisome Proliferator-Activated Receptor (PPAR)β/δ ameliorates these pathologies partly through its anti-inflammatory effects. PPARβ/δ activation prevents the production of inflammatory cytokines by adipocytes, and it is involved in the acquisition of the anti-inflammatory phenotype of macrophages infiltrated in adipose tissue. Furthermore, PPARβ/δ ligands prevent fatty acid-induced inflammation in skeletal muscle cells, avoid the development of cardiac hypertrophy, and suppress macrophage-derived inflammation in atheroscler...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>ReplyWe appreciate the interest and comments about our article. Drs Tariq and Mitchell state that some literature on Stratus OCT report retinal thinning in diabetics with minimal or no diabetic retinopathy (DR)?in contrast to our article, which reported no thinning compared with controls. Drs Tariq and Mitchell also ask whether such discrepancy between studies may be accounted for by correcting for the effects of race, age, and sex on retinal thickness (as we did in our study). This is an excellent point and, in our opinion, a very important consideration when designing or interpreting studies with OCT-based outcomes. (Source: American Journal of Ophthalmology)Media Type: Textbook Synopsis: It is rare for any book to be both informative and entertaining, much less a medical textbook. But, with a wealth of practical information conveyed in a jaunty, almost irreverent style, Dr. Jonathan Walker's Diabetic Retinopathy for the Comprehensive Ophthalmologist manages to be just that. (Source: American Journal of Ophthalmology)Macular Thickness in Diabetic Subjects Without RetinopathyThe recent report by Kashani and associates analyzing retinal thickness by race, gender, and age adds to the growing literature on optical coherence tomography measured retinal parameters in different populations. Kashani and associates reported Stratus OCT measurements of macular parameters in white, black, and Hispanic individuals of both sexes, including those with diabetes but without retinopathy. They reported no significant differences in the macular parameters of individuals with diabetes without retinopathy compared with controls, using data adjusted for race, gender, and age group. They also reported that mean foveal thickness and foveal center point thickness were statistically greater in males than in females. Black persons had a significantly thinner mean foveal thickness and c...Too much spent on diabetes drugsToo much is being spent by the NHS on diabetes drugs, which take 7% of the UK prescribing budget, researchers have claimed (Source: Nursing in Practice)No Effect of Selenium Supplementation on Serum Glucose Levels in Men with Prostate CancerConclusion: These results do not support a relationship between selenium supplementation and changes in serum glucose levels. Recommendations about selenium supplementation and risk of diabetes will require more definitive studies. (Source: The American Journal of Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Not Your Otitis Media 101A 58-year-old man with diabetes mellitus presented with a left earache and decreased hearing. Despite antibiotic treatment for otitis media, followed by treatment with another antibiotic and wick placement for refractory otitis media and newly diagnosed otitis externa, dizziness and headache developed. (Source: The American Journal of Medicine)Health Insurance and Cardiovascular Disease Risk FactorsConclusion: The treatment and control of hypertension and hypercholesterolemia are lower among uninsured adults. Increasing the proportion of insured individuals may be a means to improve the treatment and control of cardiovascular disease risk factors and to reduce health disparities. (Source: The American Journal of Medicine)Depression and Incident Diabetic Foot Ulcers: A Prospective Cohort StudyConclusion: Major depression by Patient Health Questionnaire-9 is associated with a 2-fold higher risk of incident diabetic foot ulcers. Future studies of this association should include better measures of peripheral neuropathy and peripheral arterial disease, which are possible confounders or mediators. (Source: The American Journal of Medicine)Effects of Acute Psychological Stress on Glucose Metabolism and Subclinical Inflammation in Patients with Post-traumatic Stress DisorderIn conclusion, acute stress induces postprandial blood glucose peaks and elevated insulin levels and a selective decrease of systemic immune markers and the proinflammatory regulator of the NFκB cascade, which are associated with type 2 diabetes. This points towards an independent effect of acute psychological stress on glucose metabolism and inflammation.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)Indomethacin Activates Peroxisome Proliferator-activated Receptor ? to Improve Insulin Resistance in Cotton Pellet Granuloma ModelHorm Metab ResDOI: 10.1055/s-0030-1261952AbstractInflammation is involved in the development of insulin resistance and diabetes. However, the effectiveness of anti-inflammatory drugs in diabetic therapy remains obscure. In the present study, the possible mechanisms of indomethacin, one of the nonsteroidal anti-inflammatory drugs, in the improvement of insulin resistance were investigated. Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue. Also, cotton pellet implantation induced impaired glucose utilization and insulin resistance were improved by indomethacin. The decrement in phosphoinsulin receptor and phospho-Akt levels induced by cotton pellet implantation w...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Poorly controlled Type 2 diabetics have decreased lung functionPatients with Type 2 diabetes who have poor glycemic control have reduced pulmonary function compared with their well-controlled peers, suggest study findings. (Source: MedWire News - Diabetes)Diabetes drugs' "spiralling costs"As much as 7% of the entire NHS budget on medicines is being spent on diabetes drugs, researchers have said (Source: Pharmacy Europe)Impact Of Childhood Obesity Goes Beyond HealthAdults who have been overweight since high school risk a lifetime of disease, discrimination and poverty. A new study of obese 40-year-olds found those who were overweight teens were three times more likely to suffer chronic health problems such as heart disease, diabetes and hypertension. They were also much more likely to be unemployed or receiving welfare.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science)One molecule, many more insulin-producing cells to treat diabetes, says Pitt team(University of Pittsburgh Schools of the Health Sciences) With a single stimulatory molecule, human insulin-producing beta cell replication can be sustained for at least four weeks in a mouse model of diabetes, according to researchers at the University of Pittsburgh School of Medicine in Diabetes. They also found several cocktails of molecules that drive human beta cells to replicate, as well as important differences between mouse and human beta cells that could influence how these approaches are best used to treat diabetes. (Source: EurekAlert! - Medicine and Health)Implanted glucose sensor works for more than 1 year(University of California - San Diego) Bioengineers at the University of California, San Diego and GlySens Incorporated have developed an implantable glucose sensor and wireless telemetry system that continuously monitors tissue glucose and transmits the information to an external receiver. The paper, published in the July 28, 2010 issue of the journal Science Translational Medicine, describes the use of this glucose-sensing device as an implant in animals for over one year. After human clinical trials and FDA approval, the device may be useful to people with diabetes as an alternative to finger sticking and short-term, needle-like glucose sensors that have to be replaced every three to seven days. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Weight-Management Web Site Helps Regular Users the MostSpending a few minutes every month on a weight-management Web site is almost as effective as having a personal coach when it comes to avoiding weight rebound, according to a Kaiser Permanente study. Medscape Medical News (Source: Medscape Today Headlines)Women with diabetes in pregnancy have increased arterial stiffnessWomen who have gestational diabetes mellitus or Type 2 diabetes in pregnancy have increased arterial stiffness compared with nondiabetic pregnant women, say researchers. (Source: MedWire News - Diabetes)Alcohol may fight rheumatoid arthritisModerate drinking has been linked to a variety of health benefits, including a reduced risk of heart disease, stroke, and diabetes. According to a new study, drinking alcohol may also ease the pain of -- and lower the risk of developing -- rheumatoid arthritis, a potentially crippling autoimmune disorder. (Source: CNN.com - Health)The evolving burden of HIV infection compared with other chronic diseases in northern Italy*The aim of the study was to estimate the burden and direct costs of diseases in HIV-infected patients (either opportunistic illnesses or other chronic diseases) with respect to the HIV-uninfected population. These estimates will be useful for the projection of future direct costs of HIV care. A population-based study was conducted in the Brescia Local Health Agency in northern Italy. An administrative database recorded diagnoses, deaths, drug prescriptions and health resource utilization for all medical and surgical patients in the region from 2003 to 2007. The study estimated the prevalence of HIV infection as well as HIV-related mortality and annual cost per patient, and compared mortality and costs related to HIV infection with those for a set of 15 other chronic diseases. The standardi...Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodelingAuthors: Mostafa M Elgebaly, Roshini Prakash, Weiguo Li, Safia Ogbi, Maribeth H Johnson, Erin M Mezzetti, Susan C Fagan
& Adviye Ergul (Source: Journal of Cerebral Blood Flow)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Magnesium intake and type II diabetes in Japanese men and women: the Japan Public Health Center-based Prospective StudyAuthors: A Nanri, T Mizoue, M Noda, Y Takahashi, K Kirii, M Inoue
& S Tsugane (Source: European Journal of Clinical Nutrition)Insulin-requiring diabetes in Ethiopia: associations with poverty, early undernutrition and anthropometric disproportionAuthors: S Fekadu, M Yigzaw, S Alemu, A Dessie, H Fieldhouse, T Girma, E R Trimble, D I W Phillips
& E H O Parry (Source: European Journal of Clinical Nutrition)Insulin modulates cytokine release and selectin expression in the early phase of allergic airway inflammation in diabetic ratsConclusion: Data presented suggest that insulin modulates the production/release of TNF-alpha and IL-1beta, the expression of P- and E-selectin, and the associated neutrophil migration into the lungs during the early phase of the allergic inflammatory reaction. (Source: BMC Pulmonary Medicine - Latest articles)Cardiovascular drugs are most commonly prescribed pillsFour of the five top prescribed drugs are for heart diseaseRelated items from OnMedicaPoor patients more likely to die after heart surgery than richNew catheter technique doubles survival after heart attackBlood sugar control in diabetics to cut heart riskAll over-55s should take blood pressure pillsPlan to switch to angioplasty for first-line heart treatment (Source: OnMedica Latest News)Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes MellitusConclusion:
The present study provides evidence that MCF2L2, ADIPOQ and SOX2 genetic polymorphisms have effects on the resistance of DN in female T1D patients, and suggests that the linkage with DN in chromosome 3q may be explained by the cumulated genetic effects. (Source: BMC Medical Genetics - Latest articles)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Transition of kidney tubule cells to a senescent phenotype in early experimental diabetesDiabetic nephropathy is the commonest cause of end-stage renal disease. Inordinate kidney growth and glomerular hyperfiltration at the very early stages of diabetes are putative antecedents to this disease. The kidney is the only organ that grows larger with the onset of diabetes mellitus, yet there remains confusion about the mechanism and significance of this growth. Here we show that kidney proximal tubule cells in culture transition to senescence in response to oxidative stress. We further determine the temporal expression of G1 phase cell cycle components in rat kidney cortex at days 4 and 10 of streptozotocin diabetes to evaluate changes in this growth response. In diabetic rats we observe increases in kidney weight-to-body weight ratios correlating with increases in expression of th...Experimental obesity drug avoids brain effects that troubled predecessorsA second-generation experimental anti-obesity and diabetes drug has shown promise in reducing body weight in rodents just as effectively as the predecessor rimonabant while avoiding the risk of psychiatric side effects that led to the withdrawal of rimonabant from the market and stopped further development of other brain-penetrating drugs of its type. (Source: ScienceDaily Headlines)Risk of Acute Myocardial Infarction, Stroke, Heart Failure, and Death in Elderly Medicare Patients Treated With Rosiglitazone or Pioglitazone [Original Contribution]Conclusion Compared with prescription of pioglitazone, prescription of rosiglitazone was associated with an increased risk of stroke, heart failure, and all-cause mortality and an increased risk of the composite of AMI, stroke, heart failure, or all-cause mortality in patients 65 years or older. (Source: JAMA)Rosiglitazone and the Case for Safety Over Certainty [Editorial](Source: JAMA)Adding Noninsulin Antidiabetic Drugs to Metformin Therapy for Type 2 Diabetes [Letters](Source: JAMA)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Adding Noninsulin Antidiabetic Drugs to Metformin Therapy for Type 2 Diabetes [Letters](Source: JAMA)Adding Noninsulin Antidiabetic Drugs to Metformin Therapy for Type 2 Diabetes--Reply [Letters](Source: JAMA)HbA1c Alone a Weak Predictor of Diabetes and Cardiovascular RiskDon't rely on hemoglobin (Hb)A1c alone to identify patients at risk for diabetes and heart disease. It's far less precise than glucose tolerance or fasting plasma glucose tests, two new studies show. Reuters Health Information (Source: Medscape Medical News Headlines)Arguments continue over the metabolic syndromeThe metabolic syndrome has been the subject of controversy for many years: to this day, agreement cannot be reached between the diabetes and cardiology communities about the validity of naming and...
For complete story visit theheart.org. (Source: theHeart.org)Ben-Gurion University of the Negev Researchers Identify Risks of Hypertension in Young AdultsJuly 27, 2010 (EurekAlert) - Ben-Gurion University of the Negev (BGU) researchers reveal in a new, large-scale study that "normal" blood pressure at age 17 can still predict hypertension at early adulthood and that teenage boys are three to four times more likely to develop high blood pressure in early adulthood than girls.
read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Ben-Gurion University of the Negev Researchers Identify Risks of Hypertension in Young AdultsJuly 27, 2010 (EurekAlert) - Ben-Gurion University of the Negev (BGU) researchers reveal in a new, large-scale study that "normal" blood pressure at age 17 can still predict hypertension at early adulthood and that teenage boys are three to four times more likely to develop high blood pressure in early adulthood than girls.
read more (Source: Diabetes News from dLife.com)CranberryThis fact sheet provides basic information about cranberry—common names, uses, potential side effects, and resources for more information. Cranberries are the fruit of a native plant of North America. These red berries are used in foods and in herbal products.What Cranberry Is Used ForHistorically, cranberry fruits and leaves were used for a variety of problems, such as wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.Recently, cranberry products have been used in the hope of preventing or treating urinary tract infections or Helicobacter pylori (H. Pylori) infections that can lead to stomach ulcers, or to prevent dental plaque. Cranberry has also been reported to have antioxidant and anticancer activity. (Source: NCCAM Featured Content)New Obesity Compound Shows Promise in MiceA compound similar to the once-promising weight loss drug Acomplia (rimonabant) helped obese mice lose weight and lower their blood lipids and blood sugar without psychological side effects, U.S. researchers said on Monday. Reuters Health Information (Source: Medscape Today Headlines)If You?re Laughing, You?re Living?LongerDear Health Conscious Reader,
Do you want to hear the funniest joke in the world?
If you do searches for the ?funniest joke in the world,? this is the most common winner for U.S. audiences?
A couple of hunters are out in the woods when one of them grabs his chest, falls to the ground, and then lies there motionless.
The other hunter calls 911. ?My friend won?t get up, and I think he?s dead! What should I do??
The operator, in a calm, soothing voice, says: ?Just take it easy. I can help. First, you have to make sure he?s dead.?
There?s a silence? then the operator hears two shots.
The hunter?s voice comes back on the line. ?Okay, what do I do next??
Now? I know jokes that I think are a lot funnier, but they?re a little too risqué to put in your letter. But...Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance [Medical_Sciences]Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes... (Source: Proceedings of the National Academy of Sciences)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic {beta}-like cells [Medical_Sciences]Diabetes mellitus is characterized by either the inability to produce insulin (type 1 diabetes) or as insensitivity to insulin secreted... (Source: Proceedings of the National Academy of Sciences)Supramolecular insulin assembly II for a sustained treatment of type 1 diabetes mellitus [Applied_Biological_Sciences]In this study,... (Source: Proceedings of the National Academy of Sciences)FDA Alert - Vialipro Dietary Supplement Recalled: Undeclared Drug IngredientThe undeclared ingredient may pose a threat to the consumer because the interaction of the analogue with some prescription drugs (such as nitroglycerin) may lower blood pressure to dangerous levels. Consumers with diabetes, high blood pressure, high cholesterol, or heart disease often take other prescription drugs. (Source: NCCAM Featured Content)The More Frequently You Log On, The More Weight You Can Keep OffJuly 27, 2010 (EurekAlert) - The more people used an interactive weight management website, the more weight loss they maintained, according to a Kaiser Permanente Center for Health Research study published online today in the open access Journal of Medical Internet Research.
read more (Source: Diabetes News from dLife.com)The More Frequently You Log On, The More Weight You Can Keep OffJuly 27, 2010 (EurekAlert) - The more people used an interactive weight management website, the more weight loss they maintained, according to a Kaiser Permanente Center for Health Research study published online today in the open access Journal of Medical Internet Research.
read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Heart news digestDanger of food firms paying for obesity campaign, diabetes timebomb and bogus collectors are in the news today (Source: BHF National News)Staff Nurse, Endocrinology - Nottingham University Hospitals NHS TrustAdded via www.healthjobsuk.com
Nottingham University Hospitals NHS Trust are seeking a dynamic and motivated registered nurse with a desire to develop leadership skills to join the team at their newly refurbished Acute Medical Ward. The Ward has a special interest in the treatment of diabetic patients.
Successful candidates will gain experience in endocrinology as a speciality as well as experience in looking after patients with general medical disorders.
The deadline for applications is 9 August 2010. For more information please follow the link below.
Further details (Source: Society for Endocrinology)At-Home Monitoring Crucial For Managing Diabetes In PetsMonitoring the blood glucose levels of diabetic pets can eliminate the life-threatening risks of low blood sugar and minimize the complications of diabetes, such as cataracts, recurring infections and pancreatitis, says veterinarian Dr. Sara Ford. Dr. Ford will be speaking on the subject of diabetes management and at-home blood glucose monitoring for diabetic pets at the 2010 American Veterinary Medical Association (AVMA) Convention on Saturday, July 31, in Atlanta. "If you're a human diabetic you monitor your blood sugar between 4-6 times a day," says Dr. Ford... (Source: Health News from Medical News Today)The physical health challenges in patients with severe mental illness: cardiovascular and metabolic risksThis supplement is the output of a roundtable discussion, attended by a multidisciplinary panel with a broad range of expertise, which includes the treatment of severe mental illness, cardiovascular disease, diabetes and pharmaceutical prescribing.
The roundtable and writing of the supplement were organised and paid for by MSD, including the payment of Steve Titmarsh, a medical writer who was involved in the preparation and editing of this document (Source: Journal of Psychopharmacology)Laparoscopic versus open cholecystectomy in diabetic patients and postoperative outcomeConclusions When feasible, LC was a safe procedure in diabetes. Open surgery with comorbidities increased the operative risks. Our study
was not randomized, and therefore selection bias to type of procedure may affect the results.
Content Type Journal ArticleDOI 10.1007/s00464-010-1248-yAuthors
Hannu Paajanen, Kuopio University Hospital Department of Surgery Kuopio FinlandSatu Suuronen, Mikkeli Central Hospital Department of Surgery Mikkeli FinlandPia Nordstrom, Mikkeli Central Hospital Department of Surgery Mikkeli FinlandPekka Miettinen, Kuopio University Hospital Department of Surgery Kuopio FinlandLeo Niskanen, Kuopio University Hospital Department of Medicine Kuopio Finland
Journal Surgical EndoscopyOnline ISSN 1432-2218Print ISSN 0930-2794 (Source: Surgi...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Calibra Gains FDA Clearance To Market Finesse? Insulin Patch-Pen For Three-Day Use With Novolog®Calibra Medical announced it received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its Finesse? insulin patch-pen for up to three-day use with Novo Nordisk's Novolog® rapid acting insulin. Combining the mealtime therapy-adherence benefits of insulin pumps with the simplicity and affordability of syringes and pens, Calibra's novel bolus-only patch-pen is a small, adhesively attached, flat device that can be operated discretely through clothing to deliver mealtime, snack time, and correction bolus insulin in seconds... (Source: Health News from Medical News Today)Reducing The Health Risks Of Obesity Without Serious Side EffectsThe drug rimonabant was developed as a treatment for obesity and its myriad of serious health consequences (for example, type 2 diabetes). Despite having its desired effects on weight, which it decreased, and on levels of glucose and fats in the blood, rimonabant was never approved for use in the US because of serious neurological side effects including depression and anxiety... (Source: Health News from Medical News Today)First Nations People On Peritoneal Dialysis At Greater Risk Of Infection And DeathFirst Nations people in Canada on peritoneal dialysis are at increased risk of peritonitis and death, irrespective of whether they live in a rural or urban location, found a study published in CMAJ (Canadian Medical Association Journal). The high prevalence of diabetes, obesity and hypertension in Canada's First Nations, or aboriginal, population is fuelling the rapid growth of kidney disease and renal failure and consequent need for care and dialysis. Peritonitis is inflammation of the peritoneum (the inner lining of the abdominal and pelvic walls), often caused by infection... (Source: Health News from Medical News Today)Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes?A growing body of evidence supports an important role for the endocannabinoid system as a regulator of appetite, body weight, and systemic metabolism, which is overactive in obesity and type 2 diabetes. While initial attempts to target this system using the cannabinoid receptor inverse agonist rimonabant were successful in producing modest weight loss and improving obesity-related metabolic complications in humans, adverse central nervous system side effects precluded introduction of this drug into clinical practice. However, new data, presented by Tam and colleagues in this issue of the JCI, demonstrate that selective blockade of peripheral cannabinoid receptors may be a novel successful therapeutic approach. (Source: Journal of Clinical Investigation)Scientists discover olive oil directly impacts genes to halt inflammation(NaturalNews) Research has been steadily accumulating that olive oil, a main component of the Mediterranean diet, has extensive health-protective properties. For example, phytonutrient components of olive oil have been found to be effective against breast cancer cells (http://www.naturalnews.com/025633_cancer_olive_oil_brst.html) and studies suggest the abundance of olive oil in the Mediterranean style of eating may be the reason that diet helps prevent depression (http://www.naturalnews.com/027265_depression_mediterranean_diet_health.html). Now scientists have discovered that phenolic compounds in olive oil directly repress genes linked to inflammation. This could be especially important in halting the dangerous effects of metabolic syndrome. Characterized by excess abdominal fat, high ch...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Early Puberty Tied To Obesity In GirlsA review of more than 100 studies found overweight girls tend to reach puberty earlier than their peers do. While some researchers have argued hitting puberty early in life makes a person at higher risk for metabolic syndrome and diabetes, Emily Walvoord, M.D., pediatric endocrinologist and review author, found such diseases are not linked to early puberty, but obesity. The review appears online in the Journal of Adolescent Health. "Early puberty is one of the many outcomes of obesity," said Walvoord, a professor at the Indiana University School of Medicine... (Source: Health News from Medical News Today)ALR Technologies Announces FDA 510(k) Filing For Health-e-Connect (HeC) System -- Health Care For Diabetes PatientsALR Technologies Inc. (OTCBB: ALRT) announces that on July 23, 2010 the Company submitted a 510(k) application to the FDA for its proprietary Health-e-Connect (HeC) System. The HeC system is an internet-based product intended for diabetic patients and their health care providers to improve communication and monitoring of patients' health management programs. One aspect of the system is that HeC will incorporate data uploaded from patients' glucometers into the ALRT database to quickly assess user compliance and performance compared to provider set targets... (Source: Health News from Medical News Today)iCo Therapeutics Inc. Receives Health Canada Clearance To Conduct Phase II DME Trial With iCo-007iCo Therapeutics Inc. (TSX VENTURE:ICO) is pleased to announce that the Therapeutic Products Directorate, a division of Health Canada, has issued a No Objection Letter response to the Company regarding its iCo-007 Phase II Diabetic Macular Edema (DME) Clinical Trial Application (CTA). "Based on our successful submission iCo may now proceed into a Phase II clinical trial for this indication in Canada, marking an enormous milestone for the company," stated Dr. Peter Hnik, iCo's Chief Medical Officer... (Source: Health News from Medical News Today)Fetal exposure to severe Chinese famine increases risk for hyperglycemiaStudy results suggest that fetal- and late-childhood exposure to the severe Chinese famine of 1959?1961 is associated with significantly increased risk for hyperglycemia or Type 2 diabetes in later life. (Source: MedWire News - Diabetes)Editorial Board(Source: Diabetes Research and Clinical Practice)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Contents(Source: Diabetes Research and Clinical Practice)Monitoring diabetes in patients and petsCOLUMBIA, Mo., July 26 (UPI) -- U.S. researchers say a diabetes monitoring device reduces the stress of obtaining multiple blood samples from patients -- whether human or animal.
Health - Diabetes mellitus - Conditions and Diseases - Endocrine Disorders - Pancreas (Source: Health News - UPI.com)Are you a diabetes timebomb? If you're slightly overweight, you could be one of a million Britons with undiagnosed diabetesA little tubbier than you'd prefer? Like a million other Britons, you could be suffering from undiagnosed diabetes, putting you at high risk of impotence, heart problems and even losing a limb... (Source: the Mail online | Health)Short sleep duration may increase impaired fasting glucose riskPeople who sleep for less than 6 hours per night have a three-fold increased risk for developing impaired fasting glucose compared with those who sleep for 6 to 8 hours per night, a US study suggests. (Source: MedWire News - Diabetes)Think before you snack: Auto-eating is part of the new obesity epidemicWITH one in four adults in the UK now dangerously overweight obesity has become a modern day plague that threatens to cause an explosion in deaths from diabetes and heart disease. Yet are diets really the solution or could we tackle our expanding waistlines more effectively by making small changes to our eating habits? (Source: Daily Express - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Low flow oxygenation of full-excisional skin wounds on diabetic mice improves wound healing by accelerating wound closure and reepithelializationOxygen-based therapies have proven effective in treating chronic and difficult-to-heal skin wounds, but the current therapeutic approaches suffer from major limitations and they do not allow for continuous wound treatment. Here we examined whether the continuous treatment of wounds with pure oxygen at low flow rates accelerates wound closure and improves wound healing in a murine model of diabetic skin wounds. Two full-excisional dorsal skin wounds were generated on 15-week-old diabetic db/db mice and treated for 10 weeks continuously with pure oxygen (>99·9%) at low flow rates (3 ml/h). After 6 days, oxygen treatment resulted in a mean reduction of the original wound size by 60·2% as compared with only 45·2% in wounds on control mice that did not receive pure oxygen.(P = 0·022). After...Protocol for a national audit on self-reported confidence levels, training requirements and current practice among trainee doctors in the UK: The Trainees Own Perception of Delivery of Care in Diabetes (TOPDOC) StudyDiscussionIt is anticipated that the results of this national study will clarify confidence levels and current practice among trainee doctors in the provision of care for people with diabetes. The responses will inform efforts to enhance postgraduate training in diabetes, potentially improving the quality of care for people with diabetes. (Source: BMC Medical Education)Magnets applied to acupuncture points as therapy: a literature reviewSource: DARE
Area: Evidence > Complementary Medicine
CRD Summary: The review concluded that further investigation of acu-magnet therapy was warranted, particularly for the management of diabetes and insomnia, however, the quality of the trials prevented treatment recommendations. Despite limitations in the review, the authors cautious conclusions are likely to be reliable.
CRD Commentary: The review question was supported by clear if broad inclusion criteria. Several databases were searched. The search was restricted by language (English and Chinese) and the authors did not systematically attempt to locate unpublished papers, thus increasing the likelihood of language and publication biases. Risk of publication bias was acknowledged by the authors. Although six reviewers performed the d...CAS and MHRA statements on cardiovascular risks associated with rosiglitazoneSource: MHRA, CAS
Area: News
Following recent reports of the increased cardiovascular risk associated with the use of rosiglitazone, the Central Alerting System and the MHRA have issued a "Dear Doctor" letter outlining current advice and information about the use of rosiglitazone (Avandia®, Avandamet®?) in the treatment of diabetes.
The letter states that a Europe-wide review of available data on the risks and benefits of rosiglitazone by the European Committee on Medicinal Products for Human Use (CHMP) is anticipated to be completed by September 2010, but in the meantime healthcare professionals should closely observe the current Contra-indications, warnings and precautions and monitoring requirements, and consider alternative treatments where appropriate.
Additio...Recommended management of type 1 diabetes with insulinInsulin therapy in type 1 diabetes aims to achieve optimal blood glucose control while avoiding troublesome hypoglycaemia. Our Drug review discusses the properties of currently available insulins, followed by sources of further information and a review of prescription data. Copyright © 2010 Wiley Interface Ltd (Source: Prescriber)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetesBackground:
Treatment guidelines recommend LDL-C as the primary target of therapy in patients with hypercholesterolemia. Moreover, combination therapies with lipid-lowering drugs that have different mechanisms of action are recommended when it is not possible to attain LDL-C targets with statin monotherapy. Understanding which treatment or patient-related factors are associated with attaining a target may be clinically relevant.
Methods:
Data were pooled from two multicenter, randomized, double-blind studies. After stabilization on simvastatin 20 mg, patients with coronary heart disease (CHD) alone and/or type 2 diabetes mellitus (T2DM) were randomized to ezetimibe 10 mg/simvastatin 20 mg (EZ/Simva) or simvastatin 40 mg. The change from baseline in low-density lipoprotein cholesterol (LDL-...Addition of Soluble Soybean Polysaccharides to Dairy Products as a Source of Dietary FiberIncreasing consumption of dietary fiber in food leads to many important health benefits: for example, reduction in blood cholesterol, reduced risk of diabetes, and improved laxation. Water soluble soybean polysaccharide (SSPS) is a dietary fiber extracted and refined from okara, a byproduct of soy manufacturing. It was incorporated into 3 categories of dairy-based products, thickened milkshake-style beverages, puddings, and low-fat ice cream, to the maximum amount without over-texturing the food. Rheological measurements and sensory tests were used to develop desirable SSPS-fortified products. From the rheological data, 4% SSPS-fortified dairy beverages and 4% SSPS -fortified puddings were in the range of commercial products. From sensory analyses, 4% SSPS-fortified dairy beverage with 0.0...The Role of Kidney-Pancreas Transplantation in Diabetic Kidney DiseaseAbstract For patients with type 1 diabetes, innovations in insulin formulations and delivery have improved the ability to achieve excellent
blood glucose control. However, it is uncommon to achieve euglycemia, particularly while avoiding complications arising from
hypoglycemia. Pancreas transplantation remains the only broadly applied treatment strategy that can result in normalization
of blood glucose, but this must be weighed against the risks of a surgical procedure and subsequent immunosuppression. To
improve this risk/benefit ratio, pancreas transplantation is typically performed in patients with kidney failure who are to
undergo kidney transplantation and immunosuppression (simultaneous pancreas-kidney transplant) or who have undergone kidney
transplant and are oblig...Rosiglitazone Revisited: An Updated Meta-analysis of Risk for Myocardial Infarction and Cardiovascular Mortality [Review Article]Conclusions Eleven years after the introduction of rosiglitazone, the totality of randomized clinical trials continue to demonstrate increased risk for MI although not for CV or all-cause mortality. The current findings suggest an unfavorable benefit to risk ratio for rosiglitazone. (Source: Archives of Internal Medicine)Lifestyle and Adiponectin Level: Four-Year Follow-up of Controlled Trials [Research Letters](Source: Archives of Internal Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Obese Kids' Feet Are Flatter and FatterObese children tend to have flatter feet than their normal-weight peers, but it has been unclear whether that reflects a potential problem in the foot's bone structure or simply extra fat padding. A new study suggests that it's both. Reuters Health Information (Source: Medscape Diabetes Headlines)Consumer Gene Test Results Misleading: U.S. ProbePeople who send off their saliva to genetic testing companies to find out their risk for prostate cancer or diabetes are likely to get different results depending on the company they choose, government investigators told lawmakers on Thursday. Reuters Health Information (Source: Medscape Pathology Headlines)Can Frozen Desserts be part of a Diabetes Meal Plan?Are you worried that you can't have ice cream, popsicles or other frozen desserts as part of your diabetes meal plan? You are not alone - this can be a challenge for many people who have diabetes. It is possible for people with diabetes to incorporate frozen desserts into a balanced diabetes meal plan. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)AmMed Direct names new CEONashville-based AmMed Direct, whose chief executive left the company in February amid an internal audit of the company?s Medicare billing practices, has named new leadership for the diabetes testing supply company. (Source: bizjournals.com Health Care:Health Insurance headlines)AmMed Direct names new CEONashville-based AmMed Direct, whose chief executive left the company in February amid an internal audit of the company?s Medicare billing practices, has named new leadership for the diabetes testing supply company. (Source: bizjournals.com Health Care:Biotechnology headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Skeleton Key: Bone Cells May Play a Part in Regulating the Body's MetabolismInsulin , the well-known blood sugar hormone, may have a newly discovered function in the body that will rattle your bones--regulating skeletal growth and breakdown.Two new studies published online July 22 in Cell show that insulin stimulates both bone building and breakdown in mice through the hormone's effects on two types of bone cells: bone-building osteoblasts and bone-resorbing osteoclasts. What's more, these cells are involved in an intricate hormonal loop that in turn regulates not only insulin production, but also blood sugar levels and energy metabolism. The studies suggest that the skeleton may be an important regulator of whole-body energy metabolism, joining the ranks of known metabolic regulators such as muscle and fat. The authors conclude that their findings have important...Fresh Air For AvandiaDrug Discovery: New diabetes drug insights may revive research efforts. (Source: Chemical and Engineering News)Muscle gene may provide new treatments for obesity and diabetesIn muscle, a protein called MED1 normally suppresses a genetic program that holds in check certain energy expenditure pathways. But when Rockefeller University scientists removed this gene in mice, a number of genes that are usually suppressed were activated, suggesting that targeting the Med1 gene could provide new therapeutical approaches to treating such metabolic diseases as obesity and diabetes. (Source: The Rockefeller University Newswire)Doctors Don?t ?Get? Their Patientsread more (Source: Diabetes News from dLife.com)Doctors Don?t ?Get? Their Patientsread more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Early Puberty Tied to Obesity in GirlsJuly 26, 2010 (Newswise) - A review of more than 100 studies found overweight girls tend to reach puberty earlier than their peers do.
While some researchers have argued hitting puberty early in life makes a person at higher risk for metabolic syndrome and diabetes, Emily Walvoord, M.D., pediatric endocrinologist and review author, found such diseases are not linked to early puberty, but obesity.
read more (Source: Diabetes News from dLife.com)Early Puberty Tied to Obesity in GirlsJuly 26, 2010 (Newswise) - A review of more than 100 studies found overweight girls tend to reach puberty earlier than their peers do.
While some researchers have argued hitting puberty early in life makes a person at higher risk for metabolic syndrome and diabetes, Emily Walvoord, M.D., pediatric endocrinologist and review author, found such diseases are not linked to early puberty, but obesity.
read more (Source: Diabetes News from dLife.com)Diabetes costs 'out of control' (BBC News Online, 26 July 2010)Researchers from Cardiff University have suggested that a large rise in spending on drugs to control blood sugar is not fully explained by a rise in the number of people with type 2 diabetes, but is also due to a rise in the use of more expensive diabetes therapies.
Full article (Source: Society for Endocrinology)Lecturer/Tutor Diabetes Nursing - King's College LondonAdded via www.jobs.ac.uk
The Florence Nightingale School of Nursing and Midwifery at King's College London are looking to recruit a well qualified nurse with specialist experience in diabetes nursing to become a Lecturer/Tutor in Diabetes Nursing. The successful applicant will work closely with Professor Angus Forbes (FEND Professor of Diabetes Nursing) to develop the School and partner Trusts as a centre for diabetes related nursing research and teaching.
Applicants for a Lectureship must hold a doctoral degree or be close to submitting their thesis and ideally be research active. Experienced nurses who hold a Bachelor's or Master's degree in Nursing or a related subject will also be considered for the role of Tutor.
The deadline for applications is 6 August 2010. For more information ...Rare And Common Genetic Variations Responsible For High Triglyceride Levels In BloodIt can make blood look like cream of tomato soup. Patients with high levels of triglycerides in their blood, a disease called hypertriglyceridemia (HTG) face an increased risk for heart disease and stroke. HTG affects one in 20 people in North America and is also associated with obesity, diabetes and pancreatitis. Most people now understand the importance of LDL, the bad cholesterol and HDL, the good cholesterol, to their overall health. But high triglycerides are like the Rodney Dangerfield of the lipid world: they get less respect and notoriety compared to their cholesterol cousins... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Bone Plays Key Role In Insulin RegulationNew US research on mice suggests that bone plays a key role in insulin regulation and helps cells of the body take up glucose; as both these processes are impaired in people with type 2 diabetes the researchers suggest this discovery could lead to new diabetes drugs. Dr Gerard Karsenty from Columbia University Medical Center, New York, and colleagues found that the process of bone resorption, when old bone breaks down to make way for new growth, releases a hormone called osteocalcin that turns on insulin production and also helps cells take up glucose... (Source: Health News from Medical News Today)Great Tastes And International Recipes That Reduce The Risk Of Heart DiseaseThe European Society of Cardiology (ESC) has announced the upcoming launch of its all-new European Cook Book. Bringing together recipes created by leading cardiologists from across its membership, the aim of this high quality book is to demonstrate that a diverse, heart-friendly diet can be achieved without compromising on taste. The ESC strongly endorses a healthy and balanced diet as an effective means of lowering the risks from conditions such as hypertension, diabetes and coronary artery disease... (Source: Health News from Medical News Today)Ohio Sets Up High Risk Pool; Four Drug Companies Come Under Scrutiny For Payments To Pittsburgh Doctors, NursesThe Associated Press/Bloomberg BusinessWeek: "Ohioans with pre-existing health conditions, such as cancer or diabetes, can apply for coverage under a new high-risk insurance pool beginning Aug. 1." Qualifications include evidence of a pre-existing condition, proof of Ohio residency and U.S... (Source: Health News from Medical News Today)Man And Man's Best Friend Benefit From Diabetes Monitoring DeviceThe treatment of diabetes was revolutionized in 1922 when insulin was isolated from dogs. Since then, significant advances in human medicine have made diabetes more manageable for patients. Now, human medicine has returned the favor and used these advances to help dogs with diabetes. A University of Missouri researcher is using a continuous glucose monitoring device - commonly used in humans with diabetes - to help treat dogs and other animals. The device, which provides a detailed glucose picture of an animal over several days, will help pet owners manage their pets' diabetes... (Source: Health News from Medical News Today)As Weight Goes Up, So Do Heart RisksTitle: As Weight Goes Up, So Do Heart RisksCategory: Health NewsCreated: 7/23/2010 12:10:00 PMLast Editorial Review: 7/26/2010 (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Shedding Pounds Saved One Woman's LifeTitle: Shedding Pounds Saved One Woman's LifeCategory: Health NewsCreated: 7/23/2010 12:10:00 PMLast Editorial Review: 7/26/2010 (Source: MedicineNet Diabetes General)Avandia's future murky after FDA panel voteThe type 2 diabetes drug, already under a black-box warning, is examined again as more questions about its safety are raised. (Source: American Medical News - PROFESSION)Diabetes costs 'out of control'The NHS is spending too much on drugs for diabetes, say researchers who found the costs of medicines to control blood sugar have spiralled in recent years. (Source: BBC News | Health | UK Edition)Diabetes risk factor for swine flu hospitalizationResults from an influenza surveillance project in Canada show that patients with diabetes who become infected with the pandemic influenza A virus are at significantly greater risk for hospitalization and intensive care unit admission than those without diabetes. (Source: MedWire News - Respiratory)Maternal family history of diabetes lowers CVD risk in diabetic womenAustralian researchers suggest that a maternal family history of diabetes may reduce the risk for cardiovascular disease in female, but not male, patients with diabetes. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Low BMI associated with increased mortality in diabetesRead the full story on MD Consult:
Low BMI associated with increased mortality in diabetes (Source: MD Consult: News: Top Stories)Effect of call-based counseling ringing trueThe therapist-patient relationship is crucial to people battling depression, addiction, weight gain and diabetes. But that relationship might not always have to be in person to be effective.
Over the last decade, numerous hospitals and clinics have begun... (Source: OrlandoSentinel: Medical Research)Effect of Call-Based Counseling Ringing TrueThe therapist-patient relationship is crucial to people battling depression, addiction, weight gain and diabetes. But that relationship might not always have to be in person to be effective.
Over the last decade, numerous hospitals and clinics have begun... (Source: OrlandoSentinel: Medical Research)Prediabetes and prehypertension in disease free obese adults correlate with an exacerbated systemic proinflammatory milieuBackground:
Obesity is a pro-inflammatory state frequently associated with widespread metabolic alterations that include insulin resistance and deregulation of blood pressure (BP). This cascade of events in some measure explains the susceptibility of obese adults for co-morbid conditions like diabetes mellitus and hypertension.Hypothesis: We hypothesized that an elevated systemic proinflammatory burden correlates with dysglycemia and deregulated blood pressure.
Methods:
We analyzed the screening anthropometric and laboratory measures from healthy disease free obese adults (n=35; women (W) 27, men (M) 8) in a weight loss study.
Results:
Healthy obese normoglycemic (fasting serum glucose: FSG (Source: Journal of Inflammation)Medical Treatment of Retinopathy of Type-2 DiabetesOphthalmologica 2004;218:291–296 (DOI:10.1159/000079469) (Source: Ophthalmologica)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Inadequate glucose control in type 2 diabetes is associated with impaired lung function and systemic inflammation: a cross-sectional studyBackground:
Inadequate glucose control may be simultaneously associated with inflammation and decreased lung function in type 2 diabetes. We evaluated if lung function is worse in patients with inadequate glucose control, and if inflammatory markers are simultaneously increased in these subjects. Methods: Subjects were selected at the Colombian Diabetes Association Center in Bogota. Pulmonary function tests were performed and mean residual values were obtained for forced expiratory volume (FEV1), forced vital capacity (FVC) and FEV1/FVC, with predicted values based on those derived by Hankinson et al. for Mexican-Americans. Multiple least-squares regression was used to adjust for differences in known determinants of lung function. We measured blood levels of glycosylated hemoglobin (HBA1c...Correlates of Echocardiographic Indices of Cardiac Remodeling Over the Adult Life Course. Longitudinal Observations From the Framingham Heart Study.Conclusions-Cardiac remodeling over the adult life course is characterized by a distinct pattern of increasing LV wall thickness, decreasing LV dimensions, and increasing fractional shortening with advancing age. Overall, female sex, greater blood pressure load, and presence of diabetes mellitus serve to attenuate this remodeling pattern. These observations suggest a mechanism for the preponderance of women with hypertension and individuals with diabetes among patients with diastolic heart failure.
PMID: 20660804 [PubMed - as supplied by publisher] (Source: Circulation)Angiotensin-I Converting Enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.Conclusions- These findings identify ACE2 as a novel target for the prevention of beta-cell dysfunction and apoptosis occurring in type 2 diabetes.
PMID: 20660625 [PubMed - as supplied by publisher] (Source: Diabetes)A Genetic Link between Obesity and MMP14-Dependent Adipogenic Collagen Turnover.Conclusions - Together, these findings demonstrate that the MMP14 gene, encoding the dominant pericellular collagenase operative in vivo, directs obesogenic collagen turnover and is linked to human obesity traits.
PMID: 20660624 [PubMed - as supplied by publisher] (Source: Diabetes)Diabetes Drug Byetta Linked to Kidney Problems by FDAByetta, a commonly prescribed diabetes drug, has been linked to kidney and pancreas problems. (Source: Disabled World)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>Diabetics can be identified in an electronic medical record using laboratory tests and prescriptionsSource: Tu K et al, Journal of Clinical Epidemiology, 2010 Content: Objective
With the increasing use of electronic medical records (EMRs) comes the potential to efficiently evaluate and improve quality of care. We set out to determine if diabetics could be accurately identified using structured data contained within an EMR.
Study Design and Setting
We used a 5% [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)Applying Ontology Techniques to Develop a Medication History Search and Alert System in Department of Nuclear MedicineSource: Chen J et al, Journal of Medical Systems, 2010 Content: Nowadays, patients usually take more than three drugs for diseases such as hypertension, diabetes, and dyslipidemia. Hence, nuclear medicine physicians should be very careful about the medication history of each patient and ensure that their medication will not cause false positive or false negative [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)Eye study finds two therapies slow diabetic eye disease progressionIn high-risk adults with Type 2 diabetes, researchers have found that two therapies may slow the progression of diabetic retinopathy, an eye disease that is the leading cause of vision loss in working-age Americans. (Source: ScienceDaily Headlines)Morning test helps doctors save kidneysA morning urine test is superior to all other tests for detecting declining kidney performance in patients with diabetic kidney disease, according to a new study. The results suggest that clinicians should monitor kidney function by measuring the albumin:creatinine ratio from a first morning urine sample. (Source: ScienceDaily Headlines)
painful. By understanding pain they also hope to understand why patients suffering from fibromyalgia have an increased pain sensitivity. Actual research has started to reveal interesting facts about the human brain. It seams that people with this disorders have reduced blood flow to the parts of the brain that usually deal with the perception of the pain. Scientists now have the help of modern technology to better conduct their tests. With special machines, they will use an unique method called positron emission therapy tomography to see the difference of blood flow between women that suffer from the diseases and women that are not suffering from the disease. Same kind of tests are being done in men so that all spectrums of the illness are best understood. After a certain amount of time results of these two tests will be compared and thoroughly analyzed. To best understand the action of many diseases. Scientists are actually using different test with lab mice. Symptoms in lab mice and rats are very similar to those felt by humans; the same thing applies to the action of the disease. First studying the long term effects on lab mice actually provides the very bases for future research done to understand and treat fibromyalgia in humans. If you want to find out more information about www.fibromyalgia-info-center.com/ please visit this website. You will also find valuable information about Fibromyalgia treatment and Fibromyalgia diet.
Here are some more diabetes articles...
Obesity Is Not The Fault Of Individuals - Know About Obesity And It‘s Medicine Acomplia.
By Rythm Desai
A new report published today supported by the UK government has revealed that individuals should not be held responsible for obesity problems. The news comes just days after the UK health secretary Read more...
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Increase Your Wellbeing: How To Survive Your Chocolate Cravings
By lazy submit
If you think your chocolate cravings are due to you suffering from prolonged stress, you need to work on the things that make you stressed such as your nutritional status, your exercise, and Read more...
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Study of 24 Hour Blood Pressure and the Association to Complications to Type 1 Diabetes
<b>Conditions</b>: Type 1 Diabetes; Hypertension<br/><b>Intervention</b>: <br/><b>Sponsor</b>: Steno Diabetes Center<br/><b>Recruiting</b> - verified April 2010
A Study on the Prevalence of Obstructive Sleep Apnea in Patients With Type II Diabetes Mellitus
<b>Conditions</b>: Obstructive Sleep Apnea; Diabetes Mellitus<br/><b>Intervention</b>: <br/><b>Sponsor</b>: The University of Hong Kong<br/><b>Completed</b> - verified July 2010
Efficacy and Safety of Ranibizumab in Two "Treat and Extend" Treatment Algorithms Versus Ranibizumab As Needed in Patients With Macular Edema and Visual Impairment Secondary to Diabetes Mellitus
<b>Condition</b>: Diabetic Macular Edema<br/><b>Interventions</b>: Drug: Ranibizumab; Drug: ranibizumab; Drug: ranibizumab<br/><b>Sponsor</b>: Novartis Pharmaceuticals<br/><b>Not yet recruiting</b> - verified July 2010
To Evaluate if Wide Glucose Fluctuations Lead to Injury of Heart Nerves
<b>Condition</b>: Type 1 Diabetes Mellitus<br/><b>Intervention</b>: <br/><b>Sponsor</b>: University of Michigan<br/><b>Recruiting</b> - verified May 2010
Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part I)
<b>Conditions</b>: Vascular Diseases; Diabetes<br/><b>Interventions</b>: Device: femoral-popliteal bypass; Device: stent<br/><b>Sponsors</b>: Peking Union Medical College Hospital; Beijing Tongren Hospital; Xuanwu Hospital, Beijing<br/><b>Not yet recruiting</b> - verified July 2010
Comparing Safety and Efficacy of NN5401 With Insulin Glargine in Subjects With Type 2 Diabetes: An Extension to Trial NN5401-3590
<b>Condition</b>: Diabetes Mellitus, Type 2<br/><b>Interventions</b>: Drug: NN5401; Drug: insulin glargine<br/><b>Sponsor</b>: Novo Nordisk<br/><b>Recruiting</b> - verified July 2010
Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin
<b>Condition</b>: Type 2 Diabetes Mellitus<br/><b>Interventions</b>: Drug: LIXISENATIDE (AVE0010); Drug: Placebo<br/><b>Sponsor</b>: Sanofi-Aventis<br/><b>Recruiting</b> - verified July 2010
Does Vitamin D Reduce Risk of Developing Type II DM in High Risk Individuals
<b>Condition</b>: Type 2 Diabetes Mellitus<br/><b>Interventions</b>: Drug: Vitamin D3; Drug: Placebo<br/><b>Sponsor</b>: King Faisal Specialist Hospital & Research Center<br/><b>Not yet recruiting</b> - verified July 2010
Does Vitamin D Improve Glycemic Control in Type II DM?
<b>Conditions</b>: Diabetes Mellitus; Vitamin D Deficiency<br/><b>Interventions</b>: Drug: vitamin D3 2000 IU; Drug: vitamin D3 5000 IU; Drug: Placebo<br/><b>Sponsor</b>: King Faisal Specialist Hospital & Research Center<br/><b>Not yet recruiting</b> - verified July 2010
Insulin Dosage Software Program for People With Type 1 and Type 2 Diabetes
<b>Conditions</b>: Diabetes; Insulin<br/><b>Intervention</b>: Device: insulin dose software<br/><b>Sponsors</b>: Park Nicollet Institute; National Institutes of Health (NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Hygieia, Inc; International Diabetes Center at Park Nicollet<br/><b>Recruiting</b> - verified June 2010
Type 2 Diabetes and Obesity in Mexican Pimas: Gene-Environment Interaction
<b>Condition</b>: Type 2 Diabetes Mellitus<br/><b>Intervention</b>: <br/><b>Sponsor</b>: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)<br/><b>Recruiting</b> - verified June 2010
Evaluation of the Effectiveness and Safety of Physician Versus Patient-led of Insulin Glargine Initiation and Titration in Type 2 Diabetes Mellitus
<b>Condition</b>: Diabetes Mellitus, Type 2<br/><b>Intervention</b>: Drug: Insulin Glargine<br/><b>Sponsor</b>: Sanofi-Aventis<br/><b>Not yet recruiting</b> - verified July 2010
A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin Therapy
<b>Condition</b>: Type 2 Diabetes<br/><b>Interventions</b>: Drug: SK-0403; Drug: Placebo; Drug: Sitagliptin<br/><b>Sponsor</b>: Kowa Research Institute, Inc.<br/><b>Not yet recruiting</b> - verified June 2010
Tu Salud Si Cuenta: UT Community Outreach Program for Community-based Diabetes Prevention and Control.
<b>Condition</b>: Diabetes, Obesity<br/><b>Intervention</b>: Behavioral: Tu Salud Si Cuenta Behavioral Intervention<br/><b>Sponsor</b>: The University of Texas Health Science Center, Houston<br/><b>Recruiting</b> - verified July 2010
Hypothalamic Function Before and After Bariatric Surgery
<b>Conditions</b>: Obesity; Diabetes<br/><b>Interventions</b>: Procedure: Roux en Y gastric bypass and lap. gastric banding; Behavioral: Prodimed dietary intervention<br/><b>Sponsor</b>: Leiden University Medical Center<br/><b>Recruiting</b> - verified January 2010
Evaluation of Single Nucleotide Polymorphisms (SNPs) in Patients With and Without Diabetic Macular Edema
<b>Conditions</b>: Diabetic Retinopathy; Diabetic Macular Edema<br/><b>Intervention</b>: <br/><b>Sponsor</b>: National Eye Institute (NEI)<br/><b>Recruiting</b> - verified July 2010
Psoriasis Inflammation and Systemic Co Morbidities
<b>Condition</b>: Psoriasis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Rockefeller University; Weill Medical College of Cornell University<br/><b>Recruiting</b> - verified July 2010
The Effectiveness of Lubiprostone in Constipated Diabetics
<b>Conditions</b>: Constipation; Diabetes; Colon Transit<br/><b>Intervention</b>: Drug: Lubiprostone<br/><b>Sponsor</b>: Emory University<br/><b>Not yet recruiting</b> - verified July 2010
Noninvasive Transcutaneous Glucometer Development
<b>Conditions</b>: Healthy; Prediabetic State (IGT); Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 1<br/><b>Intervention</b>: <br/><b>Sponsor</b>: InLight Solutions<br/><b>Completed</b> - verified February 2008
Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation
<b>Conditions</b>: Mitral Valve Insufficiency; Atrial Fibrillation; Heart Failure<br/><b>Intervention</b>: Procedure: Cardiac catheterization<br/><b>Sponsors</b>: Kaohsiung Veterans General Hospital.; National Science Council, Taiwan<br/><b>Recruiting</b> - verified June 2010
Comprehensive Analyses of Multidetector-row Cardiac Computed Tomography Data in Koreans
<b>Condition</b>: Coronary Disease<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Seoul National University Bundang Hospital; The Korean Society of Lipidology and Atherosclerosis<br/><b>Recruiting</b> - verified June 2010
Effect of Recombinant Human Growth Hormone (rhGH) Administration on Visceral Adiposity and Markers of Cardiovascular Risk in Obese Adolescent Girls
<b>Condition</b>: Obesity<br/><b>Interventions</b>: Drug: recombinant human growth hormone (rhGH); Drug: Placebo<br/><b>Sponsors</b>: Massachusetts General Hospital; Genentech<br/><b>Recruiting</b> - verified July 2010
Characterization of the Kinetics of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and in Subjects With Type 2 Diabetes Mellitus (T2DM)
<b>Condition</b>: Type 2 Diabetes Mellitus<br/><b>Intervention</b>: Drug: Dapagliflozin<br/><b>Sponsor</b>: Bristol-Myers Squibb<br/><b>Not yet recruiting</b> - verified July 2010
Prevention of Postprandial Hyperglycemia by Acarbose May be a Promising Therapeutic Strategy for Reducing the Increased Risk for Cardiovascular Disease.
<b>Condition</b>: Diabetes Mellitus<br/><b>Intervention</b>: Drug: Glucobay (Acarbose, BAYG5421)<br/><b>Sponsor</b>: Bayer<br/><b>Completed</b> - verified July 2010
Efficacy and Safety of Basal-bolus Therapy, Comparing Stepwise Addition of Insulin Aspart Versus Complete Basal-bolus Regimen
<b>Condition</b>: Diabetes Mellitus, Type 2<br/><b>Interventions</b>: Drug: insulin aspart; Drug: insulin detemir; Drug: insulin aspart; Drug: insulin detemir<br/><b>Sponsor</b>: Novo Nordisk<br/><b>Not yet recruiting</b> - verified July 2010
Effect of Pioglitazone on Mitochondrial Function in Muscle and Adipose Tissue in Humans
<b>Condition</b>: Type II Diabetes Mellitus<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Arizona State University; Takeda Pharmaceuticals North America, Inc.<br/><b>Recruiting</b> - verified July 2010
Vitamin D in Vulnerable Adults
<b>Conditions</b>: Frail Elderly; Vitamin D Deficiency<br/><b>Interventions</b>: Dietary Supplement: vitamin D; Dietary Supplement: placebo<br/><b>Sponsor</b>: Department of Veterans Affairs<br/><b>Not yet recruiting</b> - verified July 2010
Left Atrial Distensibility and Left Ventricular Filling Pressure in Acute Myocardial Infarction
<b>Condition</b>: Myocardial Infarction<br/><b>Intervention</b>: Procedure: Primary percutaneous coronary intervention<br/><b>Sponsors</b>: Kaohsiung Veterans General Hospital.; No other funding source in this study<br/><b>Completed</b> - verified December 2007
Use of Bevacizumab in Trabeculectomy Surgery
<b>Conditions</b>: Glaucoma; Optic Neuropathy; Fibrosis<br/><b>Interventions</b>: Drug: Bevacizumab; Drug: Control<br/><b>Sponsors</b>: Sunnybrook Health Sciences Centre; Glaucoma Research Society of Canada<br/><b>Recruiting</b> - verified July 2010
Safety and Efficacy Study Comparing 3 New Types of Coronary Stents
<b>Conditions</b>: Coronary Artery Disease; Stents; Coronary Thrombosis<br/><b>Interventions</b>: Device: coronary stent placement; Device: Coronary stent placement; Device: coronary stent placement<br/><b>Sponsor</b>: University Hospital, Basel, Switzerland<br/><b>Recruiting</b> - verified July 2010
Establishment of Biomarkers for Fabry Disease
<b>Condition</b>: Fabry Disease<br/><b>Intervention</b>: Other: Fluorescein angiography<br/><b>Sponsors</b>: Ohio State University; Genzyme<br/><b>Not yet recruiting</b> - verified July 2010
The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) Study
<b>Conditions</b>: Infant; Obesity<br/><b>Interventions</b>: Behavioral: Child Safety Insights; Behavioral: Child Feeding Insights<br/><b>Sponsors</b>: Penn State University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)<br/><b>Not yet recruiting</b> - verified July 2010
Anticholinergic vs. Botox Comparison Study
<b>Conditions</b>: Urge Urinary Incontinence; Overactive Bladder Syndrome<br/><b>Interventions</b>: Drug: Botulinum toxin A (Botox A®); Drug: Solifenacin 5mg; Drug: Solifenacin 10mg; Drug: Trospium chloride<br/><b>Sponsors</b>: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Office of Research on Women's Health (ORWH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)<br/><b>Recruiting</b> - verified June 2010
Reducing Dietary Energy Density by Incorporating Vegetables in Order to Decrease Energy Intake
<b>Condition</b>: Obesity<br/><b>Intervention</b>: Other: Incorporating vegetables into the diet to reduce energy density<br/><b>Sponsors</b>: Penn State University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)<br/><b>Active, not recruiting</b> - verified July 2010
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How To Get Out Of Going To Your Own Funeral - Grave News
By Kacy Carr
A healthier outlook on life is the answer to prevent an early death.If you continue to neglect your body then you may as well be digging an early grave for yourself. Family members will Read more...
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