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Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" ...
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Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01)
Funding Opportunity Number: RFA-DK-10-004 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: Food and NutritionHealthCFDA Number: 93.847Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationPrivate instit...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Foods high in meat and fat confer increased risk for diabetes in all ethnic groups
Foods high in meat and fat appear to confer an increased risk for diabetes in all ethnic groups, whereas the effects of other dietary patterns vary by gender and ethnicity, say US researchers. (Source: MedWire News - Diabetes)
Descending Necrotising Mediastinitis, A Fatal Disease to Keep in Mind
We report an unusual case of primary retropharyngeal abscess complicated by descending necrotising mediastinitis and bilateral empyema in a 56-year-old diabetic man. The diagnosis of descending necrotising mediastinitis (DNM) was established by the characteristic findings on computed tomography. The patient was treated by cervicotomy and staged bilateral posterolateral thoracotomy. (Source: Heart, Lung & Circulation)
Impact of Chronic Kidney Disease on Platelet Function Profiles in Diabetes Mellitus Patients With Coronary Artery Disease Taking Dual Antiplatelet Therapy
Conclusions: In DM patients with coronary artery disease taking maintenance aspirin and clopidogrel therapy, impaired renal function is associated with reduced clopidogrel-induced antiplatelet effects and a greater prevalence of HPPR. (Source: Journal of the American College of Cardiology)
Determinants of Coronary Calcium Conversion Among Patients With a Normal Coronary Calcium Scan: What Is the ?Warranty Period? for Remaining Normal?
Conclusions: Among individuals with CAC = 0, conversion to CAC >0 is nonlinear and occurs at low frequency before 4 years. No clinical factor seems to mandate earlier repeat CAC scanning. (Source: Journal of the American College of Cardiology)
Single and unhappily married men are at 64% higher risk of dying from stroke
Men who were single in the 1960s were 64% more likely to suffer a fatal stroke over the next three decades than their married counterparts.The risk of fatal stroke was also 64% higher in men who reported dissatisfaction with their marriages than in men who rated their marriages as successful.That figure is comparable to the risk of fatal stroke faced by men with diabetes.References:Single Men Have Higher Risk of Stroke. WebMD.Image source: CT scan slice of the brain showing a right-hemispheric ischemic stroke (left side of image). Wikipedia, GNU Free Documentation License.
Posted at Clinical Cases and Images. Stay updated and subscribe, follow on Twitter and Buzz, and connect on Facebook. (Source: Clinical Cases and Images)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Medical care costs among patients with established cardiovascular disease.
CONCLUSIONS: The economic burden of providing care to patients with CVD may be substantially greater than current American Heart Association estimates. Although several comorbid conditions undoubtedly contribute to these costs, avoidance of secondary CVD hospitalization may be the key to substantially reducing healthcare consumption.
PMID: 20205493 [PubMed - in process] (Source: The American Journal of Managed Care)
Diabetic kidney disease: act now or pay later.
Authors: Atkins RC, Zimmet P
PMID: 20213919 [PubMed - in process] (Source: American Journal of Nephrology)
Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The Elderly
Purchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers... (Source: Cholesterol News From Medical News Today)
The American Diabetes Association Encourages Community Organizations To Join The Movement To Stop Diabetes
The American Diabetes Association announced today their efforts to further engage community organizations across the country in raising awareness about the seriousness of diabetes and its complications through the Association's Stop Diabetes movement. The American Diabetes Association is rolling out a Stop Diabetes Community Outreach Toolkit to help community and faith-based organizations, health clinics, libraries, hospitals, fraternal groups and corporations raise awareness of diabetes risk factors among their constituents... (Source: Health News from Medical News Today)
Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The Elderly
Purchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers. Metabolic drugs, which are used to lower cholesterol levels, keep diabetes under control and for weight and thyroid problems, topped the list of the five leading categories of drugs purchased by the elderly... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Glycated Hemoglobin Tests See Increasing Use
Glycated hemoglobin (HbA1c) testing is one of the success stories of point-of-care diagnostics, and an area that will experience higher growth rates than other POC tests as a result of expert recommendations, new cases and booming mail-in test sales, according to the new report "Point-of-care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," by healthcare market research publisher Kalorama Information. The test measures glucose attached to the blood protein hemoglobin, a well-established analyte related to the long-term evaluation of blood sugar control... (Source: Health News from Medical News Today)
The American Diabetes Association Encourages Community Organizations To Join The Movement To Stop Diabetes
The American Diabetes Association announced today their efforts to further engage community organizations across the country in raising awareness about the seriousness of diabetes and its complications through the Association's Stop Diabetes movement... (Source: Diabetes News From Medical News Today)
Glycated Hemoglobin Tests See Increasing Use
Glycated hemoglobin (HbA1c) testing is one of the success stories of point-of-care diagnostics, and an area that will experience higher growth rates than other POC tests as a result of expert recommendations, new cases and booming mail-in test sales, according to the new report "Point-of-care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," by healthcare market rese... (Source: Diabetes News From Medical News Today)
Recent Studies Link Obesity To Food Allergies
First Lady Michelle Obama's "Let's Move" Campaign tells us that about 32 percent of children and teens (or 25 million) are obese or overweight. It revealed those extra pounds put them at greater risk of developing debilitating and costly diseases including diabetes, high blood pressure and high cholesterol and may also cause them to lead a two to five year shorter life than their parents... (Source: Health News from Medical News Today)
Recent Studies Link Obesity To Food Allergies
First Lady Michelle Obama's "Let's Move" Campaign tells us that about 32 percent of children and teens (or 25 million) are obese or overweight. It revealed those extra pounds put them at greater risk of developing debilitating and costly diseases including diabetes, high blood pressure and high cholesterol and may also cause them to lead a two to five year shorter life than their parents... (Source: Allergy News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
No mortality benefit in reducing HbA1c below 9%
There is little to gain in terms of reduced mortality from continually lowering HbA1c targets in patients with type 2 diabetes, a Dutch study has concluded. (Source: Pulse)
Frequent napping linked to increased risk of type 2 diabetes in older adults
A study shows that frequent napping is associated with an elevated prevalence of type 2 diabetes and impaired fasting glucose in an older Chinese population. (Source: ScienceDaily Headlines)
New alterations found in young adults with type 2 diabetes
(Institute for Research in Biomedicine (IRB Barcelona)) Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A study at the IRB Barcelona and Trinity College in Dublin demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise. (Source: EurekAlert! - Medicine and Health)
Insurers Test Health Plans that Stress Patient Choices
Workers at a Portland, Ore., steel mill soon will be able to pick a new type of insurance that offers free care for some illnesses, such as diabetes or depression, but requires hefty extra fees for treatments deemed overused, including knee replacements, hysterectomies and heart bypass surgery. (Source: RWJF News Digest - Quality/Equality)
New alterations found in young adults with type 2 diabetes
Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A new study demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Diabetes' link to eating disorders explored
(Medical College of Georgia) Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. (Source: EurekAlert! - Biology)
Depression plus diabetes may = dementia
SEATTLE, March 10 (UPI) -- Diabetes combined with depression increases dementia risk, University of Washington researchers found. (Source: Health News - UPI.com)
Measurement of Adiponectin Production from Differentiated Metabolic Stem Cells
Horm Metab ResDOI: 10.1055/s-0030-1248304AbstractTo treat metabolic syndrome, fat tissue dysfunction should be corrected rather than controlling conventional risk factors such as hypertension, dyslipidemia, and diabetes mellitus. For this purpose, accumulating evidence suggests increasing plasma adiponectin levels can be a key treatment strategy, especially in setting of food or drug selection. Here we report that adipocyte precursors obtained from several sites of fat tissue, which we call Metabolic Stem Cells (MSC), could be used as a novel screening system to identify adiponectin enhancing drugs or food for individual patients. MSC were prepared from fat tissues collected from 29 patients. They were differentiated in cultures into mature adipocytes. The time course of adiponectin produc...
ZenBio Licenses An Important Cell Line From Harvard To Drive Metabolic Disease Research
ZenBio announce that they will be a commercial source for the popular murine 3T3-L1 cell line, which has been fundamental in metabolic disease research for 30 years. Originally derived from Swiss mouse embryo tissue by Dr. Howard Green of the Department of Cell Biology at Harvard Medical School, the 3T3-L1 system has been pivotal in advancing the understanding of basic cellular mechanisms associated with diabetes, obesity and other related disorders... (Source: Health News from Medical News Today)
An observational study of type 2 diabetes within a large Australian tertiary hospital pediatric diabetes service
Conclusions: At present, T2DM in youth remains a low burden on our services. Patients with this diagnosis, however, have significant problems that present a major challenge to the development of effective management strategies. (Source: Pediatric Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Comparison of Humalog Mix 50 with human insulin Mix 30 in type 2 diabetes patients during Ramadan
Conclusion: Changing to humalog Mix 50 during Ramadan resulted in improvement in glycaemic control without increasing the incidence of hypoglycaemia. (Source: International Journal of Clinical Practice)
Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) [ggr]
Obesity is one of the predisposing factors for the development of overt Type 2 diabetes (T2D). T2D is caused by a combination of insulin resistance and [bgr]-cell failure and can be treated with insulin sensitizing drugs that target the nuclear receptor peroxisome proliferator-activated receptor (PPAR) [ggr]. Extracts of elderflowers (Sambucus nigra) have been found to activate PPAR[ggr] and to stimulate insulin-dependent glucose uptake suggesting that they have a potential use in the prevention and/or treatment of insulin resistance. Bioassay-guided chromatographic fractionation of a methanol extract of elderflowers resulted in the identification of two well-known PPAR[ggr] agonists; [agr]-linolenic acid and linoleic acid as well as the flavanone naringenin. Naringenin was found to activa...
Diamyd Medical: Diamyd US Phase III Study Well Under Way
Diamyd Medical (STO:DIAMB)(Pink Sheets:DMYDY) announces today that one hundred study participants have been included in the ongoing US Phase III study, DiaPrevent. The global Phase III program with the company's lead drug candidate Diamyd® has thereby enrolled more than 430 children newly diagnosed with type 1 diabetes in Europe and the USA. One hundred patients are now enrolled in the company's US Phase III study called DiaPrevent at 33 diabetes centers throughout the USA and more sites will be added... (Source: Health News from Medical News Today)
Diamyd Medical: Diamyd US Phase III Study Well Under Way
Diamyd Medical (STO:DIAMB)(Pink Sheets:DMYDY) announces today that one hundred study participants have been included in the ongoing US Phase III study, DiaPrevent. The global Phase III program with the company's lead drug candidate Diamyd® has thereby enrolled more than 430 children newly diagnosed with type 1 diabetes in Europe and the USA... (Source: Diabetes News From Medical News Today)
Treatment of Gestational Diabetes Does Not Affect Childhood BMI
While treatment of gestational diabetes markedly reduces macrosomia at birth, it does not reduce the infant's risk of a high body mass index (BMI) in early childhood. Reuters Health Information (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Thiazolidinediones Don't Cause Macular Edema: Study
Thiazolidinediones don't seem to cause macular edema in type 2 diabetics, the ACCORD Study Group reports. Reuters Health Information (Source: Medscape Medical News Headlines)
Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01)
Request for Applications from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBP{alpha} in human umbilical vein endothelial cells from gestational diabetes
Conclusion
The hCHOP–C/EBP complex down-regulates SLC29A1 expression in an NO-dependent manner in HUVECs from gestational diabetes. (Source: Cardiovascular Research)
Insulin glargine effective for treating nonobese and obese Type 2 diabetics
Results from a subgroup analysis of the ATLANTUS trial show that treatment with insulin glargine is effective for lowering glycated hemoglobin, without substantial weight gain, in obese and nonobese individuals with Type 2 diabetes. (Source: MedWire News - Diabetes)
Editorial Board
(Source: Diabetes Research and Clinical Practice)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Sitagliptin: A Review of its Use in the Management of Type 2 Diabetes Mellitus
(Source: Drugs)
Hemoglobin A1c outperforms fasting glucose for risk prediction
Measurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose, according to a new study. HbA1c levels accurately predict future diabetes, and they better predict stroke, heart disease and all-cause mortality as well. (Source: ScienceDaily Headlines)
Missing published and unpublished data in guidelines
(Source: BMJ Online First)
Features at Diagnosis of 324 Patients With Acromegaly Did Not Change Fom 1981 to 2006: Acromegaly Remains Under-recognized and Under-diagnosed
Traditionally, acromegaly evaded diagnosis until in its clinically obvious later stages when treatment is more difficult. Clinical Endocrinology (Source: Medscape Today Headlines)
One's Enough: People Who Donate a Kidney Live Just as Long as Those Who Don't
Every 30 minutes, all of the blood in our bodies is filtered through two fist-size kidneys. But diseases such as diabetes can cause them to fail, leading to a build-up of chemicals in the blood that without dialysis (mechanical blood filtration) or a kidney transplant would be fatal. And the wait for a new kidney can be long, unless someone you know is willing to give one of theirs to you. [More] (Source: Scientific American Topic - Medical Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Endocrinology & Diabetes Research Associate - University of Manchester
Added via the University of Manchester jobs page.
The Endocrinology and Diabetes group at the University of Manchester have an exciting opening for a postdoctoral Research Associate for up to 5 years, funded by a Wellcome Trust fellowship programme awarded to Professor Neil Hanley.
The successful applicant will study the mechanisms by which pancreatic beta-cells arise during development, with the aim of providing new insights into beta-cell regeneration. Evidence of a productive research background, ideally relating to the pancreas, is required.
The deadline for applications is 18 March 2010. Please visit the University of Manchester jobs page (below) for more information.
Further details (Source: Society for Endocrinology)
One's Enough: People Who Donate a Kidney Live Just as Long as Those Who Don't
Every 30 minutes, all of the blood in our bodies is filtered through two fist-size kidneys. But diseases such as diabetes can cause them to fail, leading to a build-up of chemicals in the blood that without dialysis (mechanical blood filtration) or a kidney transplant would be fatal. And the wait for a new kidney can be long, unless someone you know is willing to give one of theirs to you. [More] (Source: Scientific American - Official RSS Feed)
Hepatitis C And Insulin Resistance - Surprising Findings
We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance occurs in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease... (Source: Health News from Medical News Today)
Hepatitis C And Insulin Resistance - Surprising Findings
We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes... (Source: Diabetes News From Medical News Today)
Diamyd Medical: Diamyd US Phase III Study Well under Way
STOCKHOLM--(HSMN NewsFeed)--Diamyd Medical (STO:DIAMB)(Pink Sheets:DMYDY ) announces today that one hundred study participants have been included in the ongoing US Phase III study, DiaPrevent. The global Phase III program with the company’s lead drug candi... Biopharmaceuticals, EndocrinologyDiamyd Medical, DiaPrevent, Diamyd, diabetes (Source: HSMN NewsFeed)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Professor Discovers Link Between Low Oxygen Levels In Body And Cancer-Aiding Protein; Could Help Treatments For Retinoblastoma, Breast Cancer
What began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma. Dolores Takemoto, a Kansas State University professor of biochemistry who was researching protein kinase C gamma in the lens of the human eye, found her work taking a fascinating turn when she discovered a correlation between the protein Coonexin46 and hypoxia -- a deficiency of oxygen which kills normal tissue cells. According to the data, Coonexin46, or Cx46, appears in the body during these levels of low oxygen... (Source: Health News from Medical News Today)
Starting Treatment Early Doubles Chance Of Success For People With Diabetes
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association. The study found that metformin, an inexpensive, generic drug that helps patients prevent dangerously high blood sugar levels, worked nearly twice as long for people who began taking it within three months of their diabetes diagnosis. This is the first study to compare metformin failure rates in a real-world, clinical practice setting... (Source: Health News from Medical News Today)
Professor Discovers Link Between Low Oxygen Levels In Body And Cancer-Aiding Protein; Could Help Treatments For Retinoblastoma, Breast Cancer
What began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma... (Source: Breast Cancer News From Medical News Today)
Starting Treatment Early Doubles Chance Of Success For People With Diabetes
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association... (Source: Diabetes News From Medical News Today)
Dr. Gabriel Cousens reveals method for reversing diabetes with raw living foods in exclusive interview
(NaturalNews) This is a "must listen" interview for anyone suffering from diabetes, obesity or blood sugar disorders. It's commercial-free and it's a free download of an MP3 file that will play on any computer or MP3 player. What you'll hear in this interview will absolutely astound you -- it rocks the world of conventional medicine and its failed diabetes treatments.This is an interview with Dr. Gabriel Cousens, founder of the Tree of Life Rejuvenation Center in Patagonia, Arizona (www.TreeofLife.nu). In this audio interview, you'll hear Dr. Cousens describe why and how consuming raw foods really works to initiate dramatic reductions in fasting blood sugar levels, effectively reversing diabetes in a matter of just a few weeks.This is essentially a cure for diabetes. Not coincidentally, Dr...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Over 130,000 cases of diabetes now linked to soda consumption, HFCS
(NaturalNews) For years, advocates of natural health have been hammering away at the message that soda causes diabetes and obesity. The soda industry, meanwhile, has remained in denial mode, mirroring the ridiculous position of the tobacco industry that "nicotine is not addictive." Soda doesn't cause diabetes, the industry claims, and it's perfectly safe to consume in essentially unlimited quantities.The Corn Refiners Association has joined the denial with its own spin campaign that seeks to convince people High-Fructose Corn Syrup (HFCS) is totally natural and completely harmless. HFCS is, of course, the primary sweetener used in sodas and soft drinks.Now comes new research presented at the American Heart Association's Cardiovascular Disease Epidemiology and Prevention annual conference i...
Nitric oxide-releasing wrap for donor organs and cloth for therapeutic socks
(American Chemical Society) Scientists in Texas are reporting development of a first-of-its-kind cloth that releases nitric oxide gas -- an advance toward making therapeutic socks for people with diabetes and a wrap to help preserve organs harvested for transplantation. The study is in ACS' Chemistry of Materials, a bi-weekly journal. (Source: EurekAlert! - Medicine and Health)
Sodium-Glucose Co-Transport Inhibitors: Progress and Therapeutic Potential in Type 2 Diabetes Mellitus
(Source: Drugs)
Diabetes drug effective if taken early
PORTLAND, Ore., March 9 (UPI) -- The sooner people with diabetes take the generic drug Metformin that helps prevent high blood sugar levels, the longer it is effective, U.S. researchers said. (Source: Health News - UPI.com)
Scotland backs saxagliptin for type-2 diabetes
People in Scotland with type-2 diabetes now have access to a wider choice of treatments after saxagliptin (Onglyza) was accepted for use within NHS Scotland. (Source: HealthcareRepublic Press Releases)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Resting Heart Rate and Metabolic Syndrome in Patients With Diabetes and Coronary Artery Disease in Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
Prev Cardiol. ****;**:**[ndash]**. The relation between the metabolic syndrome (MetS) and resting heart rate (rHR) in patients with diabetes and coronary artery disease is unknown. The authors examined the cross-sectional association at baseline between components of the MetS and rHR and between rHR and left ventricular ejection fraction in the population from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized clinical trial. The mean rHR in the MetS group was significantly higher than in those without (68.4±12.3 vs 65.6±11.8 beats per min, P=.0017). The rHR was higher (P (Source: Preventive Cardiology)
Drug utilization of oral hypoglycemic agents in a university teaching hospital in India
Conclusion: This study strongly highlights the need for patient education or counselling on use of antidiabetic and concomitant drugs, monitoring of blood glucose and glycosylated haemoglobin (HbA1c) levels, diet control, and correction of diabetic complications. Metabolic control was poor and HbA1c monitoring was underutilized. Clinical monitoring of patients' adherence to prescribed treatments is recommended and measures should be taken to improve it. (Source: Journal of Clinical Pharmacy and Therapeutics)
JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial
DiscussionThe aim of this study is to evaluate the effectiveness and safety of JinQi JiangTang (JQJT) tablets for the treatment of patients with pre-diabetes.Trial registrationChinese clinical trials register ChiCTR-TRC-00000401 (Source: Trials)
Non-Langerhans cell histiocytosis with isolated CNS involvement: An unusual variant of Erdheim-Chester disease
We report a 58-year-old Caucasian woman who presented with diabetes insipidus and was found to harbor a large suprasellar mass. Histopathological analysis was consistent with non-LCH. The differential diagnoses included juvenile xanthogranuloma, adult-onset xanthogranuloma, xanthoma disseminatum, Rosai-Dorfman disease, and Erdheim-Chester disease. Immunohistochemical examination demonstrated a proliferation of large lipid-laden histiocytic cells which were positive for CD68, negative for S100 protein, and showed only faint, background staining for CD1a. We present a case of an autopsy-confirmed non-Langerhans cell histiocytosis limited to the central nervous system and evaluated with both immunohistochemical and ultrastructural studies. Based on the multifocality, anatomic distribution, an...
A high-protein low-fat diet is more effective in improving blood pressure and triglycerides in calorie-restricted obese individuals with newly diagnosed type 2 diabetes
Authors: E Papakonstantinou, D Triantafillidou, D B Panagiotakos, A Koutsovasilis, M Saliaris, A Manolis, A Melidonis
& A Zampelas (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus
Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced the commencement of the "Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus" trial (SAVOR-TIMI 53), a multicenter, randomized, double-blind, placebo-controlled Phase 4 study, to evaluate treatment with ONGLYZA? (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor, in adult type 2 diabetes patients with cardiovascular risk factors. (Source: World Pharma News)
iViva Bien!: Overcoming Recruitment Challenges in a Multiple-Risk-Factor Diabetes Trial
Conclusions: Using appropriate recruitment procedures, a representative sample of Latinas can be obtained. (Source: American Journal of Health Behavior)
March is "Save Your Vision" Month
Did you know that diabetic retinopathy is a leading cause of blindness in the U.S. today? According to the National Diabetes Information Clearinghouse, between 12,000 to 24,000 new cases of blindness every year are attributed to diabetes.
If you have diabetes, what can you do to protect your vision?
Try to keep your blood sugar levels in a normal range. High blood sugar can damage delicate blood vessels in the eye.
Visit an eye doctor regularly for checkups.
If you notice any changes in your vision, call your eye doctor immediately.
More from your diabetes guide...
What to Know About Diabetic Retinopathy
Photo courtesy of Medioimages/Photodisc/Getty Images
March is "Save Your Vision" Month originally appeared on About.com Diabetes on Wednesday, March 10th, 2010 at 01:03:01.Permalink | ...
WBC linked to metabolic syndrome risk, severe psychiatric symptoms in schizophrenia
White blood cell count may be useful for predicting the metabolic syndrome and more severe psychiatric symptoms in non-diabetic patients with schizophrenia, say US researchers. (Source: MedWire News - Psychiatry)
Protect Your Kidneys, Control Diabetes, Op-ed
NOTE: The following is an op-ed piece by Susan MacNeil, manager, Nova Scotia Renal Program.
Diabetes is the leading cause of kidney disease. More than 40 per cent of people that need dialysis also have diabetes. (Source: Government of Nova Scotia News Releases - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Beneficial Effects of L- and N-type Calcium Channel Blocker on Glucose and Lipid Metabolism and Renal Function in Patients with Hypertension and Type II Diabetes Mellitus
This study was undertaken to compare the efficacy of amlodipine (an inhibitor of L-type calcium channels) and cilnidipine (an inhibitor of both L-type and N-type calcium channels) in patients with hypertension and type II diabetes mellitus. Seventy-seven hypertensive patients were divided into two groups according to presence/absence of type II diabetes mellitus. In these two groups of patients, the effects of amlodipine and cilnidipine on glucose and lipid metabolism and renal function were compared. As for glucose and lipid metabolism, homeostasis model assessment insulin resistance (HOMA-R) level in the non-diabetic group and triglyceride in the diabetes group were significantly lower with cilnidipine than with amlodipine. As regards renal function in the diabetic group, estimated glome...
Paradoxical Decrease in High-Density Lipoprotein Cholesterol with Fenofibrate: A Quite Rare Phenomenon Indeed
Some recent clinical reports have suggested that paradoxical decreases in high-density lipoprotein cholesterol (HDL-C) levels after fenofibrate treatment may be quite common. These appear to occur mainly in patients with combined fibrate/statin therapy and possibly in those with low baseline HDL-C. Reports on HDL-C reductions after fenofibrate are possibly supported by the disappointing results in terms of HDL-C responses from the recent FIELD study. A survey on 581 patients treated for 1 year or longer was carried out in our Clinical Center. This indicated that paradoxical HDL-C reductions are a relatively uncommon phenomenon. Not more than 15.3% of the present series showed an HDL-C reduction, mostly of a modest degree. Further, reductions of HDL-C appear to occur mainly in individuals w...
Targeting the pentose phosphate pathway in syndrome X-related cardiovascular complications
Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance, and hypertension) that affects at least one in five people in developed countries. Syndrome X shortens life and increases morbidity by contributing to the development of both diabetes and cardiovascular disease. Type 1 or 2 diabetes affects approximately 170 million people globally, and these numbers are rapidly rising. In patients with diabetes, vascular diseases develop early and progress at an accelerated rate. It has recently become evident that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme in the pentose-phosphate pathway and its reaction products play key roles in regulating...
Evaluation of risk of overall mortality in patients with type 2 diabetes receiving glipizide, glyburide, or glimepiride monotherapy
Source: Diabetes Care
Area: News
According to research published early online in Diabetes Care, glimepiride may be the preferred sulfonylurea in those with underlying coronary artery disease (CAD).
Researchers evaluated the relationship of individual sulfonylureas and the risk of overall mortality in a cohort of patients with type 2 diabetes. The retrospective cohort study was conducted using an academic health centre enterprise-wide electronic health record (EHR) system to identify 11,141 patients with type 2 diabetes (4,279 initiators of monotherapy with glyburide, 4,325 initiators of monotherapy with glipizide, and 2,537 initiators of monotherapy with glimepiride), aged >18 years, with and without a history of CAD, and not on insulin or a non-insulin injectable at baselin...
DURATION-1: Exenatide once weekly produces sustained glycaemic control and weight loss
Source: Diabetes Care
Area: News
According to research published early online in Diabetes Care, exenatide once weekly elicited sustained improvements in glycaemic control and body weight through 52 weeks of treatment.
The results were obtained from a sub-analysis of the DURATION-1 trial, in which the safety and efficacy of 30 weeks of treatment with the exenatide once weekly (2mg) was compared to exenatide twice daily, in 295 patients with type 2 diabetes.
The sub analysis evaluated the safety and efficacy of exenatide once weekly in a) patients who continued treatment for an additional 22 weeks (52 weeks total), and b) patients who switched from exenatide twice a day to exenatide once weekly after 30 weeks. A total of 258 patients entered the 22-week open-ended asse...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations
Conclusions: The study shows a relatively high proportion of GCK mutations among individuals with GCK-like phenotype, confirming the effectiveness of carefully applied clinical criteria prior to genetic testing. In the Czech MODY registry, GCK-MODY represents the biggest subgroup of MODY (35%). We report several prevalent GCK mutations with a likely founder effect in the Czech population. Furthermore, our results provide ground for a possible recommendation to reinspect all negative results previously obtained by screening using dHPLC. (Source: Pediatric Diabetes)
Relation of subepicardial adipose tissue thickness and clinical and metabolic parameters in obese prepubertal children
Conclusions: Our study on obese prepubertal children showed that SATT was significantly correlated with age, BMI, WC, HC, MAC, TSF, insulin, and HOMA-IR. (Source: Pediatric Diabetes)
Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies
Delli AJ, Lindblad B, Carlsson A, Forsander G, Ivarsson S-A, Ludvigsson J, Marcus C, Lernmark Å; for the Better Diabetes Diagnosis (BDD) Study Group. Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies. Aim: To determine whether type 1 diabetes mellitus (T1DM) patients, having parents who immigrated to Sweden, have increased T1DM risk before 18 yr compared with countries of origin. We also determined whether they have different human leukocyte antigen (HLA) genetic markers and islet autoantibodies at diagnosis compared with Swedish patients. Methods: A total of 1988 (53% males) newly diagnosed and confirmed T1DM patients (Source: Pediatric Diabetes)
Use of continuous glucose monitoring in young children with type 1 diabetes: implications for behavioral research
Conclusions: CGM is an acceptable research tool for obtaining glucose data in young children with T1DM and has been used previously in older children and adults. CGM may be particularly useful in young children who often experience more glucose variability. Data obtained via CGM are richer and more detailed than traditional SMBG data and allow for analyses to link blood glucose with behavior. (Source: Pediatric Diabetes)
Dexamethasone effective for treating diabetic macular edema
Intravitreous treatment with dexamethasone is well tolerated and significantly improves visual acuity in patients with persistent diabetic macular edema, report researchers. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Evaluation of neopterin levels in patients undergoing hemodialysis
Neopterin is a diagnostic or a prognostic biomarker for several pathologies including renal diseases. However, the association between neopterin status and causative main reasons such as diabetes and hypertension for renal disease remains unclear. The aim of the study was to evaluate neopterin levels in diabetes and hypertension patients treated with/without hemodialysis. According to primary renal disorders, the patients undergoing hemodialysis were classified into 4 groups as diabetic nephropathy, hypertensive nephropathy, reflux nephropathy or interstitial nephritis, and others. The controls consisted of healthy subjects, hypertensive subjects, and diabetic individuals without any renal disorder. In the study, both urinary and serum neopterin levels were measured using high performance ...
Analysis of Health Utility Data When Some Subjects Attain the Upper Bound of 1: Are Tobit and CLAD Models Appropriate?
Conclusions: When the intention of the analysis is to inform an economic evaluation, and the utilities should be bounded above at 1, CLAD, and Tobit methods were biased. OLS coupled with robust standard errors or the nonparametric bootstrap is recommended as a simple and valid approach. (Source: Value in Health)
Insulin Regimens in Type 2 Diabetes
To the Editor: In the Treating to Target in Type 2 Diabetes (4-T) study, Holman et al. (Oct. 29 issue)1 ... (Source: New England Journal of Medicine)
The Predictors of Patient–Physician Race and Ethnic Concordance: A Medical Facility Fixed-Effects Approach
To examine the predictors of patient[ndash]physician race/ethnicity concordance among diabetes patients in an integrated delivery system. Kaiser Permanente's Northern California Diabetes Registry of 2005. Logistic regression predicted concordance for each racial/ethnic group. Availability of a concordant physician, whether a patient chose their physician, and patient language were main explanatory variables. The study population consisted of 109,745 patients and 1,750 physicians. Patients who chose their physicians were more likely to have a same race/ethnicity physician with OR of 2.2 (95 percent CI 1.74[ndash]2.82) for African American patients, 1.71 (95 percent CI 1.44[ndash]2.04) for Hispanic patients, 1.11 (95 percent CI 1.04[ndash]1.18) for white patients, and 1.38 (95 percent CI 1.2...
Warnings, Recommendations Fail to Improve Monitoring of Use of Atypical Antipsychotic Drugs
An important warning about atypical, or second-generation, antipsychotic drugs and a connection to increased risk for diabetes and hyperglycemia didn't make it to primary care physicians, according to a new study in the Archives of General Psychiatry. (Source: AAFP Clinical Care and Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Estimated County-Level Prevalence of Diabetes and Obesity--United States, 2007 [From the Centers for Disease Control and Prevention]
(Source: JAMA)
Link Between Hepatitis C And Insulin Resistance Surprises Scientists
Scientists in Australia found that when they studied insulin resistance in people with Hepatitis C little or none of it was in the liver and nearly all the insulin resistance occured in muscle, which surprised them because Hepatitis C is a liver disease that not only leads to cirrhosis and cancer, but also makes people three to four times more likely to develop Type 2 diabetes. You can read about the study that led to these findings in the March 2010 issue of the journal Gastroenterology, which is also available online... (Source: Health News from Medical News Today)
Link Between Hepatitis C And Insulin Resistance Surprises Scientists
Scientists in Australia found that when they studied insulin resistance in people with Hepatitis C little or none of it was in the liver and nearly all the insulin resistance occured in muscle, which surprised them because Hepatitis C is a liver disease that not only leads to cirrhosis and cancer, but also makes people three to four times more likely to develop Type 2 diabetes... (Source: Diabetes News From Medical News Today)
10 Tips to Ease Concerns About Your Weight
Given the focus on weight by the health establishment, the government and the media, it is not surprising that many people in this country are anxiously asking the same question. And there is no shortage of recommendations out there directing people to lose weight with this or that diet, lifestyle program or eating regimen.
Unfortunately, the research over the last 25 years is quite clear. There is simply no evidence that any of these approaches results in long-term weight loss for the vast majority of people who engage in them. There are no exceptions and none of the approaches (low fat, low calorie, low carb, etc.) work any better than any of the others.
Even more unfortunately however, this complete lack of evidence does not stop people from being seduced into trying to lose weight with...
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats [Research Articles]
In this study, we investigated the effect of FXR activation by 6-ethyl-chenodeoxycholic acid, (6E-CDCA, 10 mg/kg) on insulin resistance and liver and muscle lipid metabolism in fa/fa rats and compared its activity with rosiglitazone (10 mg/kg) alone or in combination with 6E-CDCA (5 mg/kg each). In comparison to lean (fa/+), fa/fa rats on a normal diet developed insulin resistance and liver steatosis. FXR activation protected against body weight gain and liver and muscle fat deposition and reversed insulin resistance as assessed by insulin responsive substrate-1 phosphorylation on serine 312 in liver and muscles. Activation of FXR reduced liver expression of genes involved in fatty acid synthesis, lipogenesis, and gluconeogenesis. In the muscles, FXR treatment reduced free fatty acid synth...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Glucose stimulates cholesterol 7{alpha}-hydroxylase gene transcription in human hepatocytes [Research Articles]
This study uncovers a novel link between hepatic glucose metabolism and bile acid synthesis. Glucose induction of bile acid synthesis may have an important implication in metabolic control of glucose, lipid, and energy homeostasis under normal and diabetic conditions. (Source: The Journal of Lipid Research)
Insulin Glargine QD Equivalent to Insulin Detemir BID for Type 2 Diabetics
Once-daily insulin glargine and twice-daily insulin detemir provided similar glycemic control for insulin-na?ve type 2 diabetics in a noninferiority trial. Reuters Health Information (Source: Medscape Medical News Headlines)
Acute necrotizing pancreatitis with pancreatic abscess due to
Sonavane A, Baradkar V, Salunkhe P, D'Souza D, Kumar SIndian Journal of Medical Microbiology 2010 28(1):64-67Acute pancreatitis occasionally presents as pancreatic abscess with complications like pleural effusion and ascites. There are several pre-disposing factors, the most common being cholelithiaisis, alcohol abuse, infective causes, trauma, and metabolic causes such as diabetic ketoacidosis, while some cases are idiopathic. Here, we report a rare case of acute necrotizing pancreatitis in a 40-year-old male who presented with pain in the abdomen, ascites and left basal pleural effusion. A computerized tomography (CT) scan showed findings suggestive of pancreatic necrosis, with abscess formation and free-fluid surrounding area. The aspirated pus sample was processed for Gram stain...
The Role of Exercise-Induced Myokines in Muscle Homeostasis and the Defense against Chronic Diseases
In conclusion, exercise-induced myokines appear to be involved in mediating both systemic as well as local anti-inflammatory effects. (Source: Journal of Biomedicine and Biotechnology)
Recurrent hypoglycaemia in a type 2 diabetes patient ? diagnostic difficulties
Hypoglycaemia is the most frequent acute complication of diabetes, regardless of the type of diabetes and the treatment method. Hormonally active tumours of the pancreas, insulinomas, which belong to digestive tract neuroendocrine tumours, constitute one of the less frequent causes of hypoglycaemia. This paper presents a case of a 60-year-old type 2 diabetes patient with recurrent hypoglycaemic events, in whom an insulin-secreting hepatic neuroendocrine tumour was diagnosed. We suggest performing a diagnostic workup taking into consideration insulinoma in patients with diabetes who experience frequent otherwise inexplicable hypoglycaemic events, particularly when they recur despite decreased dose or discontinuation of hypoglycaemic agents. (Source: Articles of Archives of Medical Science -...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Adrenocorticotrophic hormone secreting pheochromocytoma
We report a rare case of pheochromocytoma of the adrenal gland presenting as Cushing syndrome. A 30 year old woman presented with pain in the left loin and classical Cushingoid features. She was a diabetic and hypertensive on treatment. Magnetic resonance imaging of the abdomen revealed a 3.5 x 3 cm mass in the left adrenal gland. Urine analysis revealed an elevated 24 hr urinary cortisol level. Clinical diagnosis was Cushing syndrome due to functioning left adrenal tumor, and hence left adrenalectomy was performed laparoscopically. Histopathological examination revealed adrenal pheochromocytoma. Immunohistochemical analysis of the tumor was positive for adrenocorticotrophic hormone and chromogranin. (Source: Indian Journal of Urology)
Assessment of plantar pressure and balance in patients with diabet
Conclusions: The data reveal a correlation between postural oscillation and peak plantar pressure on the hindfoot. (Source: Articles of Archives of Medical Science - TERMEDIA publishing house)
Bristol-Myers Squibb and AstraZeneca Announce the Commencement of the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus Trial (SAVOR-TIMI 53)
PRINCETON, N.J. & WILMINGTON, Del.--(HSMN NewsFeed)--Bristol-Myers Squibb Company (NYSE: BMY ) and AstraZeneca (NYSE: AZN ) today announced the commencement of the “Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus” tr... Biopharmaceuticals, Cardiology, EndocrinologyBristol-Myers Squibb, AstraZeneca, ONGLYZA, saxagliptin, diabetes (Source: HSMN NewsFeed)
Bezafibrate and serum amyloid A-low-density lipoprotein complex in patients with type 2 diabetes mellitus and hypertriglyceridemia.
Authors: Kotani K, Satoh N, Yamada T
PMID: 20206863 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Clinical factors that influence the cardiovascular morbidity in patients with type II Diabetes Mellitus.
Authors: Kyriazis I, Mendrinos D, Saridi M
PMID: 20206869 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Anemia in diabetic patients at an internal medicine ward: Clinical correlates and prognostic significance.
CONCLUSION: Frequency of anemia was increased in diabetic patients admitted to the Internal Medicine Departments, compared to the studies performed on ambulatory patient populations. Anemia was multifactorial and associated with higher mortality, predominantly from infections. Males with albuminuria and heart failure were at higher risk of death.
PMID: 20206878 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Children?s launches new stem cell Web site
By Jonathan Kraft, president of The Kraft Group and New England Patriots
As a long-time supporter of stem cell research, I’m proud to announce the launch of a new Children’s Hospital Boston Web site that we hope will demystify the science of stem cells and answer some of the public’s questions about them. For the past three and a half years, my wife, Patti, and I have served as co-chairs of Children’s Hospital Boston?s Stem Cell Task Force because we believe that stem cells hold incredible promise for the future of health care. During this time I?ve gotten to know Len Zon and George Daley, the two physician-scientists who head up the hospital?s Stem Cell Research Program, and I believe that the work they are doing will revolutionize health care.They?ve expl...
Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus
Duru Nilgun Selcuk, Acar Hurtan, Ayta Semih, Elevli MuratNeurology India 2010 58(1):136-137 (Source: Neurology India)
Antidiabetic Effect of Gynostemma pentaphyllum Tea in Randomly Assigned Type 2 Diabetic Patients*
This study shows a prompt improvement of glycemia and insulin sensitivity, and thereby provides a basis for a novel, effective, and safe approach, using tea, to treat type 2 diabetic patients.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
High basic fibroblast growth factor increases CHD risk in Type 2 diabetics
Elevated plasma basic fibroblast growth factor immunoreactivity increases coronary heart disease risk in men with Type 2 diabetes, report researchers. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Licorice ? or more?
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0029-1224123AbstractA 57 yr old man presented to endocrinology clinic with a six year history of poorly controlled hypertension which was treated with Metoprolol 200 mg/day and Enalapril 20 mg/day. He was asymptomatic but incidentally hypokalaemia was detected while having cholecystectomy, two years prior to his clinic appointment. He had never been on diuretics or laxatives. He was started on potassium supplements (120 mmol/d) and advised to increase dietary potassium by the surgical team. A detailed personal history revealed ingestion of 300–500 g licorice per day. Physical examination was unremarkable apart from increased blood pressure of 180/105 mmHg. Following the initial visit, his serum electrolyes (K+3....
Lipid Peroxidation and Antioxidant System in Rats Acutely Treated with Acetone
The objective of the present study was to determine the effects of acute treatment (AT) with acetone on the oxidative and metabolic status of rats. The AT group (n=16) was treated by gavage with a single administration of 7.0 g acetone/kg body weight at a concentration of 25% (m/v). Eight rats were euthanized 6 h later (AT6) and eight 24 h later (AT24). Acetone levels were determined in blood and urine and oxidative parameters were analyzed by determining thiobarbituric acid reactive species (TBARS, indicators of lipid peroxidation) and reduced glutathione (GSH) and vitamin E as antioxidant parameters. Serum glucose, blood cholesterol and triglycerieds and hepatic fat were also determined. The results indicated a significant difference in the hepatic oxidative parameters,...
Genetic Associations of IL1RN Polymorphisms with Metabolic Syndrome in a Korean Population
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1248288AbstractMetabolic syndrome (MetS) is rapidly growing into one of the major public health issues worldwide. Interleukin 1 receptor antagonist (IL1Ra) functions as a competitor of proinflammatory cytokines and has an important role in metabolic functions, including insulin secretion. To identify the relationship between the interleukin 1 receptor antagonist gene and MetS, we genotyped nine single nucleotide polymorphisms (SNPs) in the gene using direct sequencing in 66 MetS patients and 346 normal subjects in the Korean population. Among the nine polymorphisms, after adjusting for age and sex, rs928940 (G>T) showed a significant association with MetS in the codominant ( 0.023) and recessive models ( 0.011). Also, rs315952 (C>T) exh...
Type 2 diabetes mellitus: A risk factor for
Conclusion: Diabetic patients are more prone and at risk to acquire H. Pylori infection. Therefore proper monitoring of blood glucose level and screening for H. pylori infection are effective preventive measures for this life threatening infection. (Source: International Journal of Diabetes in Developing Countries)
Hypoglycemic effect of aqueous extract of
Conclusion: The aqueous extract of Trichosanthes dioica has antihyperglycemic action. (Source: International Journal of Diabetes in Developing Countries)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Free radical scavenging activity of
Rathod N R, Raghuveer I, Chitme H R, Chandra RIndian Journal of Pharmaceutical Sciences 2009 71(6):615-621Swarnabhasma , an Ayurvedic preparation containing Calotropis gigantea R. Br. (Asclepiadaceae) is extensively used by Ayurvedic physicians for treatment of diabetes mellitus, bronchial asthma, rheumatoid arthritis and nervous disorders. In the present study, we report the effect of chloroform extracts of Calotropis gigantea leaf and flower on free radical scavenging activity, and lipid profile in streptozotozin-induced diabetic rats. The lipid peroxidation, superoxide dismutase, and catalase were measured in liver homogenate and serum glutamic pyruvic transaminase, serum glutamic oxaloacetic transaminase, alkaline phosphatase, lipid profile were measured in blood serum. Administration ...
High basic fibroblast growth factor increases CHD risk in Type 2 diabetics
Elevated plasma basic fibroblast growth factor immunoreactivity increases coronary heart disease risk in men with Type 2 diabetes, report researchers. (Source: MedWire News - Heart Failure)
Blunting of the Heart Rate Response to Adenosine and Regadenoson in Relation to Hyperglycemia and the Metabolic Syndrome
Adenosine and regadenoson cause an increase in heart rate (HR) during myocardial perfusion imaging (MPI). It has been shown that patients with diabetes mellitus have a blunted HR response due to cardiac autonomic dysfunction. It is not known whether the HR response is related to hyperglycemia and the metabolic syndrome (MS). HR changes were assessed in 2,000 patients (643 with diabetes mellitus [DM]) in the Adenoscan Versus Regadenoson Comparative Evaluation for Myocardial Perfusion Imaging (ADVANCE MPI 1 and ADVANCE MPI 2) trials in relation to MS status and blood sugar level on the day of MPI. The HR response was lower in patients with MS (32.43 ± 0.52% vs 36.15 ± 0.71%, p (Source: The American Journal of Cardiology)
Prognostic Value of an Exaggerated Exercise Blood Pressure Response in Patients With Diabetes Mellitus and Known or Suspected Coronary Artery Disease
The prognostic value of an exaggerated exercise systolic blood pressure response (EESBPR) remains controversial. Our aim was to assess whether an EESBPR is associated with the long-term outcome in patients with diabetes mellitus and known or suspected coronary artery disease (CAD). From an initial population of 22,262 patients with known or suspected CAD who underwent treadmill exercise electrocardiography or exercise echocardiography at our institution, 2,591 patients with a history of diabetes mellitus were selected for the present study. EESBPR was defined as systolic blood pressure >220 mm Hg during exercise. The end points were all-cause mortality and hard events (ie, death or myocardial infarction). A total of 236 patients (9.1%) developed an EESBPR during the tests. During a mean fo...
Does Getting Fat Protect against Fat?
Everyone knows that obesity is bad for your health. Packing on the pounds, we’re told, leads to all sorts of medical problems: high cholesterol, insulin resistance, greater risk of diabetes and heart disease. But researchers at the University of Texas Southwestern Medical Center see things a little differently. In a paper in the journal Trends in Endocrinology and Metabolism [see http://bit.ly/bKaP33 ], they argue that being fat can actually protect us from these disorders. [More] (Source: Scientific American - Official RSS Feed)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Macular ischaemia after intravitreal bevacizumab injection in patients with central retinal vein occlusion and a history of diabetes and vascular disease
(Source: British Journal of Ophthalmology)
Vision-related quality of life in persons with unilateral branch retinal vein occlusion using the 25-item National Eye Institute Visual Function Questionnaire
Conclusions
BRVO is a retinal vascular disease that is associated with a decrease in vision-related quality of life as determined by the VFQ-25. A decrease in VFQ-25 score is correlated with involved eye visual acuity, even when good visual acuity is maintained in the uninvolved eye. (Source: British Journal of Ophthalmology)
Taxing junk food improves health outcomes, study finds
(Source: BMJ Online First)
Obesity As Protection Against Metabolic Syndrome, Not Its Cause
The collection of symptoms that is the metabolic syndrome - insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke - are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are... (Source: Cholesterol News From Medical News Today)
Obesity As Protection Against Metabolic Syndrome, Not Its Cause
The collection of symptoms that is the metabolic syndrome - insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke - are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are. In fact, says Roger Unger of the University of Texas Southwestern at Dallas, obesity is the body's way of storing lipids where they belong, in fat tissue, in an effort to protect our other organs from lipids' toxic effects... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Obesity as protection against metabolic syndrome, not its cause
The collection of symptoms that is the metabolic syndrome -- insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke -- are all related to obesity, but, according to a new review not in the way you probably think they are. (Source: ScienceDaily Headlines)
Intermountain Healthcare And Toshiba Announce Ultrasound Substudy Of FaCTor64 - Speckle Tracking By Echo
Cardiovascular death is the most common cause of mortality among Type 2 diabetics and claims the lives of millions each year, with many diabetics experiencing their first "symptom" as a heart attack or sudden death. Understanding that diabetics are at high risk for Coronary Heart Disease (CHD) and that many with the disease are asymptomatic, Toshiba America Medical Systems, Inc., has sponsored Speckle Tracking by Echo, a faCTor64 substudy using Toshiba's Wall Motion Tracking ultrasound technology... (Source: Health News from Medical News Today)
Higher Fast Food Prices Lead To Lower Weight, Diabetes Risk
A new study that followed participants for 20 years shows both weight and risk for diabetes decreased for people in communities where fast food prices increased. The University of North Carolina at Chapel Hill study, published in the March 8, 2010, issue of Archives of Internal Medicine, also showed the reverse when fast food prices fell, then consumption, weight and diabetes risks rose... (Source: Health News from Medical News Today)
Intermountain Healthcare And Toshiba Announce Ultrasound Substudy Of FaCTor64 - Speckle Tracking By Echo
Cardiovascular death is the most common cause of mortality among Type 2 diabetics and claims the lives of millions each year, with many diabetics experiencing their first "symptom" as a heart attack or sudden death. Understanding that diabetics are at high risk for Coronary Heart Disease (CHD) and that many with the disease are asymptomatic, Toshiba America Medical Systems, Inc... (Source: Cardiovascular / Cardiology News From Medical News Today)
Higher Fast Food Prices Lead To Lower Weight, Diabetes Risk
A new study that followed participants for 20 years shows both weight and risk for diabetes decreased for people in communities where fast food prices increased. The University of North Carolina at Chapel Hill study, published in the March 8, 2010, issue of Archives of Internal Medicine, also showed the reverse when fast food prices fell, then consumption, weight and diabetes risks rose... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Eye Disease Linked To Weakened Brain Power In People With Diabetes
Diabetic retinopathy, the leading cause of blindness in the UK's working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research¹ announced this week at leading health charity Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years old. Participants completed seven tests looking at memory, logic and concentration to establish their level of brain function... (Source: Health News from Medical News Today)
Is There A Link Between Drinking Too Many Sugary Drinks And Diabetes?
A new study claims that having sugary drinks every day could put people at a greater risk of developing Type 2 diabetes and heart disease. American researchers found that the excessive consumption of sugary drinks, which can contain up to 200 calories each, contributed to 130,000 cases of Type 2 diabetes and 14,000 cases of heart disease between 1990 and 2000 in the USA. The researchers also concluded that sugary drinks are fuelling the obesity epidemic... (Source: Health News from Medical News Today)
Eye Disease Linked To Weakened Brain Power In People With Diabetes
Diabetic retinopathy, the leading cause of blindness in the UK's working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research¹ announced this week at leading health charity Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years old... (Source: Diabetes News From Medical News Today)
Is There A Link Between Drinking Too Many Sugary Drinks And Diabetes?
A new study claims that having sugary drinks every day could put people at a greater risk of developing Type 2 diabetes and heart disease. American researchers found that the excessive consumption of sugary drinks, which can contain up to 200 calories each, contributed to 130,000 cases of Type 2 diabetes and 14,000 cases of heart disease between 1990 and 2000 in the USA... (Source: Diabetes News From Medical News Today)
Surprising findings about Hepatitis C and insulin resistance
(Research Australia) We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Starting treatment early doubles chance of success for people with diabetes
(GolinHarris International) The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association. (Source: EurekAlert! - Medicine and Health)
Surprising findings about Hepatitis C and insulin resistance
Scientists have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease. (Source: ScienceDaily Headlines)
Starting treatment early doubles chance of success for people with diabetes
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a new study. (Source: ScienceDaily Headlines)
Soft Drink and Juice Consumption and Risk of Physician-diagnosed Incident Type 2 Diabetes: The Singapore Chinese Health Study
Soft drinks and other sweetened beverages may contribute to risk of type 2 diabetes and obesity. However, research has not addressed higher risk and Asian populations. The authors examined the association between soft drinks and juice and the risk of type 2 diabetes among Chinese Singaporeans enrolled in a prospective cohort study of 43,580 participants aged 45–74 years and free of diabetes and other chronic diseases at baseline. The incidence of physician-diagnosed type 2 diabetes was assessed by interview and validated; 2,273 participants developed diabetes during follow-up. After adjustment for potential lifestyle and dietary confounders, participants consuming ≥2 soft drinks per week had a relative risk of type 2 diabetes of 1.42 (95% confidence interval (CI): 1.25, 1.62) comp...
The Association Between the Peroxisome Proliferator-Activated Receptor-{gamma}2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis
The peroxisome proliferator-activated receptor- gene (PPARG) has been implicated in the etiology of type 2 diabetes mellitus and has been investigated in numerous epidemiologic studies. In this Human Genome Epidemiology review, the authors assessed this relation in an updated meta-analysis of 60 association studies. Electronic literature searches were conducted on September 14, 2009. Population-based cohort, case-control, cross-sectional, or genome-wide association studies reporting associations between the PPARG Pro12Ala gene variant (rs1801282) and type 2 diabetes were included. An updated literature-based meta-analysis involving 32,849 type 2 diabetes cases and 47,456 controls in relation to the PPARG Pro12Ala variant was conducted. The combined overall odds ratio, calculated by per-all...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Alendronate Induces Mineralization in Mouse Osteoblastic MC3T3-E1 Cells: Regulation of Mineralization-Related Genes
In conclusion, low-dose alendronate induced mineralization in mouse osteoblastic cells. The regulation of PC-1, osteocalcin and ALP by alendronate might play some role in these effects.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Diabetes classification switch to force wave of patient reviews
GPs will have to re-assess around 40% of people with type-1 diabetes and 6% with type-2 diabetes, following the development of a new classification system. (Source: HealthcareRepublic Independent Nurse News)
Diabetes, Insulin and Alzheimer's Disease
series:Research and Perspectives in Alzheimer's DiseaseNeurons share more similarities with insulin-producing pancreatic islet cells than with any other cell type. The root of this similarity may lie in the islet?s evolution from an ancestral insulin-producing neuron. The islet-neuron connection becomes less surprising as we learn more about insulin?s involvement in functions far from its traditional role in mediating glucose uptake in muscle. The ... (Source: Springer Biomedical Sciences titles)
Simple pharmacometric tools for oral anti-diabetic drug development: competitive landscape for oral non-insulin therapies in type 2 diabetes
In conclusion, the ability of system-specific parameters to predict HbA1c provides a tool to predict the expected efficacy profile from abbreviated dose-finding trials. To be commercially viable, new drugs should improve [Delta]HbA1c by about 0.8% or more and possess safety profiles similar to newer anti-diabetic agents. Thus, this study proposes a suite of simple yet powerful tools to guide type-2-diabetes drug development. Copyright © 2010 John Wiley & Sons, Ltd. (Source: Biopharmaceutics and Drug Disposition)
Another Advantage to Nursing the Baby
Newborn mice who receive their mother's milk experience a biological process that boosts their metabolism, possibly lowering the risk of obesity and diabetes in adulthood, according to a new study.
Breast-feeding confers several protective benefits in... (Source: OrlandoSentinel: Medical Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats
Conclusions and implications: We conclude that in DM enhanced myofilament Ca2+ sensitivity is mainly manifested in muscular-type blood vessels and thus likely to contribute to the development of hypertension. Both PKC and, in particular, ROCK are involved in this phenomenon. This highlights their potential usefulness as drug targets in the pharmacological management of DM-associated vascular dysfunction. (Source: British Journal of Pharmacology)
Diabetics with a more interactive relationship style have reduced mortality
Patients with diabetes who have a ?more interactive? relationship style and who are more inclined to seek social support when needed have lower 5-year mortality than those who do not, show study results. (Source: MedWire News - Diabetes)
Crevicular fluid matrix metalloproteinase-8, -13, and TIMP-1 levels in type 2 diabetics
Conclusions: Within the limits of this study, DM does not seem to significantly affect GCF levels of MMP-8, MMP-13, TIMP-1 or clinical periodontal status. (Source: Oral Diseases)
Laparoscopic radical prostatectomy is feasible and effective in 'fit' senior men with localized prostate cancer
OBJECTIVETo assess the effect of age and comorbidity on short-term complications, long-term continence and oncological outcome after laparoscopic radical prostatectomy (LRP) for localized prostate cancer.PATIENTS AND METHODS In all, 2048 consecutive men underwent LRP for localized prostate cancer in one institution. Comorbidity was assessed using the Charlson index. Short-term postoperative complications, transfusion rate, duration of hospital stay, long-term continence and oncological outcome were analysed by age and comorbidity classes.RESULTS Of the 2048 men, 297 were aged [ge]70 years and 281 had a Charlson index of >0 (mainly diabetes 31%, chronic pulmonary disease 26%, prior other nonmetastatic cancer 16%, prior myocardial infarction 12%). Compared with younger men, senior men had si...
Comparison of sex hormonal and metabolic profiles between omnivores and vegetarians in pre- and post-menopausal women.
Authors: Karelis AD, Fex A, Filion ME, Adlercreutz H, Aubertin-Leheudre M
The purpose of the present study was to investigate the sex hormonal and metabolic profiles in vegetarians and compare these with the profiles in omnivores. The design of the present study was cross-sectional. The study sample of pre- and post-menopausal women included forty-one omnivores and twenty-one vegetarians. Thereafter we determined: (1) plasma sex hormones, (2) fasting insulin, NEFA as well as apo-A and apo-B, (3) BMI, (4) a dietary profile (3 d dietary records), (5) physical activity and (6) total faecal excretion per 72 h and total urinary excretion per 72 h. Vegetarians showed higher levels of sex hormone-binding globulin (SHBG), apo-A, total faecal excretion per 72 h and total fibre intake as well as...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Effects of metformin on glucose metabolism of perfused rat livers.
Authors: de Souza Silva FM, Rocha Alves da Silva MH, Bracht A, Eller GJ, Constantin RP, Yamamoto NS
Although metformin has been used to treat type 2 diabetes for several decades, the mechanism of its action on glucose metabolism remains controversial. To further assess the effect of metformin on glucose metabolism this work was undertaken to investigate the acute actions of metformin on glycogenolysis, glycolysis, gluconeogenesis, and ureogenesis in perfused rat livers. Metformin (5 mM) inhibited oxygen consumption and increased glycolysis and glycogenolysis in livers from fed rats. In perfused livers of fasted rats, the drug (concentrations higher than 1.0 mM) inhibited oxygen consumption and glucose production from lactate and pyruvate. Gluconeogenesis and ureogenesis from alanine we...
Effect of Long-Term Intraperitoneal Zinc Administration on Liver Glycogen Levels in Diabetic Rats Subjected to Acute Forced Swimming.
This study aims to examine the effect of zinc administration on liver glycogen levels of rats in which diabetes was induced with streptozotocin and which were subjected to acute swimming exercise. The study was conducted on 80 adult Sprague-Dawley male rats, which were equally allocated to eight groups: group 1, general control; group 2, zinc-administrated control; group 3, zinc-administrated diabetic control; group 4, swimming control; group 5, zinc-administrated swimming; group 6, zinc-administrated diabetic swimming; group 7, diabetic swimming; group 8, diabetic control group. In order to induce diabetes, animals were injected with 40 mg/kg intraperitoneal (ip) streptozotocin. The injections were repeated in the same dose after 24 h. Animals which had blood glucose at or above 300 mg/dl...
Evidence of Interaction between Type 2 Diabetes Susceptibility Genes and Dietary Fat Intake for Adiposity and Glucose Homeostasis-Related Phenotypes
J Nutrigenet Nutrigenomics 2009;2:225–234 (DOI:10.1159/000259341) (Source: Karger Publishers)
Add diabetes to Ont. school policy: parents
Some Ontario families with school-aged children requiring medical attention for conditions such as Type 1 diabetes have major concerns about a health and education policy currently under review. (Source: CBC | Health)
Randomized Controlled Trial of an Intravitreous Dexamethasone Drug Delivery System in Patients With Diabetic Macular Edema [Clinical Trial]
Conclusions In eyes with persistent DME, treatment with 700 µg of intravitreal dexamethasone DDS is well tolerated and produces significant improvements in BCVA, central retinal thickness, and fluorescein leakage compared with observation (statistically significant at day 90).
Application to Clinical Practice Dexamethasone DDS, 700 µg, may have potential as a treatment for persistent DME.
Trial Registration clinicaltrials.gov Identifier: NCT00035906 (Source: Archives of Opthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Errors in Byline and Text in: Association Between Erythropoietin Gene Polymorphisms and Diabetic Retinopathy [Correction]
(Source: Archives of Opthalmology)
Lack of Association Between Thiazolidinediones and Macular Edema in Type 2 Diabetes: The ACCORD Eye Substudy [Clinical Sciences]
Conclusions In a cross-sectional analysis of data from the largest study to date, no association was observed between thiazolidinedione exposure and DME in patients with type 2 diabetes; however, we cannot exclude a modest protective or harmful association.
Trial Registration clinicaltrials.gov Identifier: NCT00542178 (Source: Archives of Opthalmology)
Food Surcharges and Subsidies: Putting Your Money Where Your Mouth Is [Editorial]
(Source: Archives of Internal Medicine)
Alcohol Consumption, Weight Gain, and Risk of Becoming Overweight in Middle-aged and Older Women [Original Investigation]
Conclusion Compared with nondrinkers, initially normal-weight women who consumed a light to moderate amount of alcohol gained less weight and had a lower risk of becoming overweight and/or obese during 12.9 years of follow-up. (Source: Archives of Internal Medicine)
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What Is Diabetes Mellitus ? By Juliet Cohen Diabetes mellitus is defined as a fasting blood glucose of 126 milligrams per deciliter (mg/dL) or more. "Pre-diabetes" is a condition in which blood glucose levels are higher than normal but not yet diabetic. can cause many complications. Acute complications (hypoglycemia, ketoacidosis or nonketotic hyperosmolar coma) may occur if the disease is not adequately controlled. Serious long-term complications include cardiovascular disease (doubled risk), chronic renal failure (diabetic nephropathy is the main cause of dialysis in developed world adults), retinal damage (which can lead to blindness and is the most significant cause of adult blindness in the non-elderly in the developed world), nerve damage (of several kinds), and microvascular damage, which may cause erectile dysfunction (impotence) and poor healing. Poor healing of wounds, particularly of the feet, can lead to gangrene which can require amputation - the leading cause of non-traumatic amputation in adults in the developed world. Diabetes is the third leading cause of death in the United States after heart disease and cancer. Over time, can lead to blindness, kidney failure, and nerve damage. These types of damage are the result of damage to small
Body's Response to Foods' Smell, Taste Could Be Diabetes Risk
Factor (HealthDay)HealthDay - THURSDAY, March 11 (HealthDay News) -- A mutation that affects
how the body responds when a person smells or tastes food may play a role
in the development of type 2 diabetes in some people, U.S. researchers
report.Big first trimester weight gain ups diabetes risk (Reuters)Reuters - Women who gain weight too quickly during the first three months of pregnancy are more prone to develop pregnancy-related diabetes, new research shows.Increasing Soda Consumption Fuels Rise in Diabetes, Heart
Disease (HealthDay)HealthDay - FRIDAY, March 5 (HealthDay News) --Increasing consumption of sugary
soft drinks contributed to 130,000 new cases of diabetes, 14,000 new cases
of heart disease and 50,000 more life-years burdened with heart disease in
the last decade, a new U.S. study finds.Processed Meat May Harm the Heart (HealthDay)HealthDay - FRIDAY, March 5 (HealthDay News) -- Conventional wisdom has dictated
that fat from red meat is a risk factor for heart disease, but a new
analysis from Harvard researchers finds it's eating processed meat -- not
unprocessed red meat -- that increases the risk for heart disease and even
diabetes.Bugs in the gut can cause obesity: study (AFP)AFP - The bugs that help digest food may also cause the body to pack on the pounds if they are not properly regulated, a new study has found.Bugs in the gut can cause obesity: study (AFP)AFP - The bugs that help digest food may also cause the body to pack on the pounds if they are not properly regulated, a new study has found.Lunchtime coffee break best for fighting diabetes (Reuters)Reuters - Drinking coffee cuts diabetes risk, new research confirms, but you may need to enjoy your java with lunch if you want to get any benefit.Whole Grains Take a Bite Out of Type 2 Diabetes Risk (HealthDay)HealthDay - WEDNESDAY, March 3 (HealthDay News) -- Brown rice is better than white
rice at reducing the risk of type 2 diabetes, but whole grains are the
most effective at lowering the risk, study findings show.A1c diabetes test is a better indicator of risk (Reuters)Reuters - A test that shows blood sugar levels over a span of several weeks is not only the best way to diagnose diabetes but also may be better at identifying who is at risk of getting diabetes than standard blood sugar tests, researchers said on Wednesday.Newer Blood Test Predicts Diabetes, Heart Disease (HealthDay)HealthDay - WEDNESDAY, March 3 (HealthDay News) -- The newer hemoglobin A1C
test predicts diabetes as well as the traditional fasting blood sugar
test, but it beats that old standard in predicting a patient's future risk
of heart disease and stroke, new research shows.
vessels, referred to as microvascular disease. is also an important factor in accelerating the hardening and narrowing of the arteries (atherosclerosis), leading to strokes, coronary heart disease, and other large blood vessel diseases. This is referred to as macrovascular disease. affects approximately 17 million people (about 8% of the population) in the United States. In addition, an estimated additional 12 million people in the United States have and don't even know it. Normally, blood glucose levels are tightly controlled by insulin, a hormone produced by the pancreas. Insulin lowers the blood glucose level. Non-insulin-dependent mellitus (NIDDM)-is due to a combination of defective insulin secretion and insulin resistance or reduced insulin sensitivity (defective responsiveness of tissues to insulin), which almost certainly involves the insulin receptor in cell membranes. In the early stage the predominant abnormality is reduced insulin sensitivity, characterized by elevated levels of insulin in the blood. Gestational also involves a combination of inadequate insulin secretion It develops during pregnancy and may improve or disappear after delivery. Even though it may be transient, gestational may damage the health of the fetus or mother, and about 20%-50% of women with gestational develop type 2 later in life.Gestational mellitus (GDM) occurs in about 2%-5% of all pregnancies. Juliet Cohen writes articles for health care guide. She also writes articles for women health and health diseases.
Here are some more diabetes articles...
Use Of Diet Pills In Treatment Of Obesity
By Franchis
Why people should treat obesity?Obesity is an ailment that necessitates careful concentration and hardheaded conduct. Lifestyle alters; exercising, cut back and weight Read more...
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Recurring Candida Could Be A Sign Of Diabetes
By James
This is an article about candida possibly being a sign of diabetes. cript Read more...
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Health Highlights: March 11, 2010 (HealthDay)
HealthDay - Here are some of the latest health and medical news developments,
compiled by the editors of HealthDay:
Body's Response to Foods' Smell, Taste Could Be Diabetes Risk
Factor (HealthDay)
HealthDay - THURSDAY, March 11 (HealthDay News) -- A mutation that affects
how the body responds when a person smells or tastes food may play a role
in the development of type 2 diabetes in some people, U.S. researchers
report.
Health Highlights: March 10, 2010 (HealthDay)
HealthDay - Here are some of the latest health and medical news developments,
compiled by the editors of HealthDay:
CDC uses shopper-card data to trace salmonella (AP)
AP - As they scrambled recently to trace the source of a salmonella outbreak that has sickened hundreds around the country, investigators from the Centers for Disease Control and Prevention successfully used a new tool for the first time ? the shopper cards that millions of Americans swipe every time they buy groceries.
Cost of Junk Food May Influence Consumption (HealthDay)
HealthDay - TUESDAY, March 9 (HealthDay News) -- When the cost of junk food
increases, people consume less of it, a new study has found.
Health Highlights: March 9, 2010 (HealthDay)
HealthDay - Here are some of the latest health and medical news developments,
compiled by the editors of HealthDay:
Adding gluten early may cause constipation in babies (Reuters)
Reuters - Giving gluten-containing foods to infants too soon may trigger long-lasting tummy troubles but more study is needed before changing recommendations for parents, Dutch researchers conclude.
Tax soda, pizza to cut obesity, researchers say (Reuters)
Reuters - U.S. researchers estimate that an 18 percent tax on pizza and soda can push down U.S. adults' calorie intake enough to lower their average weight by 5 pounds (2 kg) per year.
Australian researchers say fat is 'sixth taste' (AFP)
AFP - It's a theory set to confirm why humans are so fond of fatty foods such as chips and chocolate cake: in addition to the five tastes already identified lurks another detectable by the palate -- fat.
Salmonella Scare Prompts Wide Product Recall (HealthDay)
HealthDay - THURSDAY, March 4 (HealthDay News) -- A wide array of food products are
being recalled after traces of salmonella were discovered in a common
ingredient, officials at the U.S. Food and Drug Administration announced
late Thursday.
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Getting Over Diabetes? Just Forget It...
By Ranju
You may or may not know the fact that according to a recent survey, in the US alone, an estimated 18,200,000 people are suffering from Diabetes. It is Read more...
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